4.7 Article

Exosomes mediate the antibody-resistant intercellular transmission of porcine epidemic diarrhea virus

Related references

Note: Only part of the references are listed.
Article Microbiology

Duck hepatitis A virus type 1 transmission by exosomes establishes a productive infection in vivo and in vitro

Guige Xu et al.

Summary: This study revealed the role of exosomes in the transmission of DHAV-1 infection and demonstrated that exosome-mediated transmission is resistant to antibody neutralization, suggesting it as an immune evasion mechanism of DHAV-1.

VETERINARY MICROBIOLOGY (2023)

Article Cell Biology

Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture

Tao Wang et al.

Summary: In this study, a new mechanism of classical swine fever virus transmission through extracellular vesicles (EVs) was discovered in cell cultures, showing that EVs are closely related to autophagy. These findings shed light on the immune evasion mechanisms of CSFV transmission and reveal new functions of cellular vesicles in virus lifecycles.

AUTOPHAGY (2022)

Article Virology

PPRV-Induced Autophagy Facilitates Infectious Virus Transmission by the Exosomal Pathway

Yangli Wan et al.

Summary: Autophagy plays a crucial role in the pathogenesis of PPRV, while the involvement of exosomes in viral infections is gaining recognition. PPRV infection can lead to packaging of viral genetic material and proteins into exosomes, promoting transmission to new target cells. This study suggests a novel mechanism involving autophagy and exosome-mediated intercellular transmission of PPRV.

JOURNAL OF VIROLOGY (2022)

Review Biochemistry & Molecular Biology

Porcine Epidemic Diarrhea: Causative Agent, Epidemiology, Clinical Characteristics, and Treatment Strategy Targeting Main Protease

Tooba N. Shamsi et al.

Summary: This study aims to investigate the causative agent, epidemiology, clinical characteristics, and treatment strategy for porcine epidemic diarrhea. The disease is a highly contagious intestinal viral infection causing severe symptoms in pigs. Currently, there is no specific treatment available for the disease, but targeting the main protease of the coronavirus could be a potential method.

PROTEIN AND PEPTIDE LETTERS (2022)

Review Virology

Porcine Coronaviruses: Overview of the State of the Art

Hanna Turlewicz-Podbielska et al.

Summary: Coronaviruses exhibit high mutation rates and recombine easily, enabling them to overcome species barriers. Six CoV can infect pigs, with different strains causing various diseases. Control of CoV infections in pigs requires rapid diagnostics and focus on biosecurity.

VIROLOGICA SINICA (2021)

Article Virology

Coronavirus Porcine Epidemic Diarrhea Virus Nucleocapsid Protein Interacts with p53 To Induce Cell Cycle Arrest in S-Phase and Promotes Viral Replication

Mingjun Su et al.

Summary: The study revealed that PEDV N protein interacts with p53 to activate the p53-DREAM pathway, inducing S-phase arrest to promote viral replication. Hyperoside, a small molecular compound, can antagonize N protein-induced S-phase arrest and inhibit viral replication by interfering with N protein-p53 interaction. These findings shed new light on PEDV-host interaction and offer a novel antiviral strategy against PEDV.

JOURNAL OF VIROLOGY (2021)

Review Neurosciences

Modern Techniques for the Isolation of Extracellular Vesicles and Viruses

Ryan P. McNamara et al.

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2020)

Review Virology

Extracellular vesicles: Vehicles of en bloc viral transmission

Nihal Altan-Bonnet et al.

VIRUS RESEARCH (2019)

Article Microbiology

Exosomes-mediated transmission of foot-and-mouth disease virus in vivo and in vitro

Keshan Zhang et al.

VETERINARY MICROBIOLOGY (2019)

Article Multidisciplinary Sciences

Arthropod EVs mediate dengue virus transmission through interaction with a tetraspanin domain containing glycoprotein Tsp29Fb

Ashish Vora et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Cell Biology

Neutral sphingomyelinases control extracellular vesicles budding from the plasma membrane

Kerstin Menck et al.

JOURNAL OF EXTRACELLULAR VESICLES (2017)

Article Virology

Phylogenetic tracking of current porcine epidemic diarrhea virus (PEDV) strains in the Philippines

Rubigilda Paraguison-Alili et al.

ARCHIVES OF VIROLOGY (2016)

Review Microbiology

Extracellular vesicles are the Trojan horses of viral infection

Nihal Altan-Bonnet

CURRENT OPINION IN MICROBIOLOGY (2016)

Article Virology

Porcine epidemic diarrhea in China

Dang Wang et al.

VIRUS RESEARCH (2016)

Review Cell Biology

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

Marina Colombo et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30 (2014)

Editorial Material Gastroenterology & Hepatology

HCV transmission by hepatic exosomes establishes a productive infection

Francois-Loic Cosset et al.

JOURNAL OF HEPATOLOGY (2014)

Article Multidisciplinary Sciences

A pathogenic picornavirus acquires an envelope by hijacking cellular membranes

Zongdi Feng et al.

NATURE (2013)

Article Multidisciplinary Sciences

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells

Vedashree Ramakrishnaiah et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Ceramide triggers budding of exosome vesicles into multivesicular Endosomes

Katarina Trajkovic et al.

SCIENCE (2008)

Review Immunology

Exosomes:: Composition, biogenesis and function

C Théry et al.

NATURE REVIEWS IMMUNOLOGY (2002)

Article Genetics & Heredity

Completion of the porcine epidemic diarrhoea coronavirus (PEDV) genome sequence

R Kocherhans et al.

VIRUS GENES (2001)