4.7 Article

Sono-processes: Emerging systems and their applicability within the (bio-) medical field

Journal

ULTRASONICS SONOCHEMISTRY
Volume 100, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.ultsonch.2023.106630

Keywords

Sonochemistry; Ultrasound; Mechanophore; Sonoelectrochemistry; Sonocatalysis; Sonocrystallization

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Sonochemistry is an emerging field that uses acoustic waves to induce physical and chemical changes, showing potential in accelerating reaction rates and altering physical properties of the system. While it has found applications in various industries, research in the (bio-)medical field mostly remains in the laboratory stage.
Sonochemistry, although established in various fields, is still an emerging field finding new effects of ultrasound on chemical systems and are of particular interest for the biomedical field. This interdisciplinary area of research explores the use of acoustic waves with frequencies ranging from 20 kHz to 1 MHz to induce physical and chemical changes. By subjecting liquids to ultrasonic waves, sonochemistry has demonstrated the ability to accelerate reaction rates, alter chemical reaction pathways, and change physical properties of the system while operating under mild reaction conditions. It has found its way into diverse industries including food processing, pharmaceuticals, material science, and environmental remediation. This review provides an overview of the principles, advancements, and applications of sonochemistry with a particular focus on the domain of (bio-) medicine. Despite the numerous benefits sonochemistry has to offer, most of the research in the (bio-)medical field remains in the laboratory stage. Translation of these systems into clinical practice is complex as parameters used for medical ultrasound are limited and toxic side effects must be minimized in order to meet regulatory approval. However, directing attention towards the applicability of the system in clinical practice from the early stages of research holds significant potential to further amplify the role of sonochemistry in clinical applications.

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