4.2 Article

Impact of COVID-19 on long-term lung function in lung transplant recipients: A single-center retrospective cohort study

Journal

TRANSPLANT INFECTIOUS DISEASE
Volume -, Issue -, Pages -

Publisher

WILEY
DOI: 10.1111/tid.14151

Keywords

COVID-19; lung function; lung transplant recipients; lung transplantation; spirometry

Ask authors/readers for more resources

This study examines the long-term lung function in lung transplant recipients after their first SARS-CoV-2 infection. The results show a significant decline in lung function at 3 months, but not at 6 and 12 months post-infection.
Available data are limited concerning long-term lung function (LF) evolution after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in lung transplant (LT) recipients. The aim of this study is to determine the effect of first SARS-CoV-2 infection on long-term LF in LT recipients. We analyzed spirometry results of LT recipients followed at our institution (March 2020 to July 2022) at 3, 6, and 12 months after first SARS-CoV-2 infection. Overall, 42 LT patients of our cohort (70%) with COVID-19 were included for long-term LF analysis. Forced expiratory volume in 1 s (FEV1) declined significantly at 3 months (-4.5%, -97 mL, 95% CI [-163; -31], p < .01), but not at 6 and 12 months (-3.9%, -65 mL, 95% CI [-168; +39], p = .21). Results were quite similar for the forced vital capacity. Spirometry values declined significantly at 3 months after COVID-19 in LT recipients, presented a mixed decline at 6 months, and no significant decline at 12 months. image .

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available