4.7 Review

Dynamic luminescent probes with stimulus responsiveness for reversible analysis and bioimaging

Journal

TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 168, Issue -, Pages -

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2023.117325

Keywords

Dynamic luminescent probes; Stimulus responsiveness; Response type; Reversible detection; Bioimaging

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In this review, the authors summarize the response types of dynamic luminescent probes and provide an overview of the latest research progress in reversible analysis and bioimaging. They also discuss the challenges and future direction of dynamic luminescent probes, aiming to stimulate more advanced designs and promote their applications in reversible luminescent sensing.
Luminescent sensing techniques have attracted considerable attention due to their great potential in environmental pollutant detection, drug quality control, disease diagnosis, and in vivo imaging. Dynamic luminescent probes have the characteristic of reversible sensing, which can achieve the dynamic monitoring of two antagonistic analytes through reversible optical signal changes caused by them. In this review, we have summarized the response types of dynamic luminescent probes for the first time, including reaction type, interaction type, and inducible type. Subsequently, we systematically overview the latest research progress of dynamic luminescent probes in reversible analysis and bioimaging, including ions, molecules, gas, pH, and temperature sensing. Finally, the challenges and future direction of dynamic luminescent probes are deeply discussed. This review is expected to stimulate more advanced design of dynamic luminescent probes, thus further promoting their applications in future reversible luminescent sensing.

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