Bimetal MOFs catalyzed Fenton-like reaction for dual-mode detection of thiamphenicol

In this work, we used a simple ultrasonic stripping method to synthesize a bimetal MOFs at room temperature as a nanoenzyme with peroxidase-like (POD-like) activity. Through bimetal MOFs catalytic Fenton-like competitive reaction, thiamphenicol can be quantitatively dual-mode detected by fluorescence and colorimetry. It realized the sensitive detection of thiamphenicol in water, and the limits of detection (LOD) were 0.030 nM and 0.031 nM, and the liner ranges were 0.1-150 nM and 0.1-100 nM, respectively. The methods were applied to river water, lake water and tap water samples, and with satisfactory recoveries between 97.67% and 105.54%.

Automated summary

In this study, we synthesized a bimetal MOFs nanoenzyme with peroxidase-like activity using a simple ultrasonic stripping method at room temperature. The thiamphenicol was quantitatively detected through bimetal MOFs catalytic Fenton-like competitive reaction by fluorescence and colorimetry. The sensitive detection of thiamphenicol in water was achieved with LOD of 0.030 nM and 0.031 nM, and liner ranges of 0.1-150 nM and 0.1-100 nM, respectively. The methods were successfully applied to water samples with satisfactory recoveries between 97.67% and 105.54%.