Chiral Betaine-Mediated Efficient Organocatalytic Asymmetric Isomerization of β,γ-Unsaturated Butenolides

An asymmetric isomerization of beta,gamma-unsaturated butenolides with a newly developed betaine catalyst at a 0.2-2 mol% loading, an improvement upon available methods that use 0.5-2.0 mol% catalyst

Automated summary

A newly developed betaine catalyst was used for an asymmetric isomerization of beta,gamma-unsaturated butenolides at a lower loading (0.2-2 mol%) compared to available methods (0.5-2.0 mol%).