4.7 Article

Transcranial Direct Current Stimulation Reverses Stroke-Induced Network Alterations in Mice

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Transcranial Direct Current Stimulation Enhances Neuroplasticity and Accelerates Motor Recovery in a Stroke Mouse Model

Valentina Longo et al.

Summary: This study evaluated the impact of bihemispheric transcranial direct current stimulation (tDCS) on poststroke functional recovery in mice. The results showed that tDCS accelerated motor recovery and increased expression of BDNF, dendritic spine density, and brain connectivity. The study suggests that tDCS could be a potential treatment for stroke and that plasma BDNF levels may serve as a circulating prognostic biomarker.

STROKE (2022)

Article Clinical Neurology

Transcranial-Direct-Current-Stimulation Accelerates Motor Recovery After Cortical Infarction in Mice: The Interplay of Structural Cellular Responses and Functional Recovery

Helene Luise Walter et al.

Summary: In this study, it was found that tDCS can promote functional recovery after stroke by impacting cellular processes such as neurogenesis and microglial activation. Cathodal tDCS showed greater effects on functional recovery, neurogenesis, and microglial activation compared to anodal tDCS.

NEUROREHABILITATION AND NEURAL REPAIR (2022)

Review Neurosciences

Introduction to spasticity and related mouse models

Frederique Wieters et al.

Summary: Spasticity, a common motor disability, involves rapid muscle contractions, increased muscle tone, and heightened reflex activity. Current therapies can alleviate symptoms but cannot reverse the pathology completely, posing challenges for targeted application.

EXPERIMENTAL NEUROLOGY (2021)

Article Neurosciences

Probing rapid network reorganization of motor and language functions via neuromodulation and neuroimaging

Gesa Hartwigsen et al.

Summary: This review explores network organization and reorganization in healthy and lesioned brains, highlighting a reliance on three general mechanisms of adaptive network plasticity for short-term reorganization and stroke-induced reorganization. These mechanisms allow for computational flexibility in maintaining and recovering function in large-scale neural networks underlying motor and cognitive functions.

NEUROIMAGE (2021)

Article Neurosciences

An analysis of the CatWalk XT and a composite score to assess neurofunctional deficits after photothrombosis in mice

J. Baermann et al.

Summary: The study evaluated CatWalk's capability for assessing functional outcomes after photothrombotic stroke in mice, finding that while CatWalk detected some impairments, a composite neuroscore may be more sensitive and precise in quantifying hemisyndromes induced by photothrombosis.

NEUROSCIENCE LETTERS (2021)

Article Multidisciplinary Sciences

Immediate and after effects of transcranial direct-current stimulation in the mouse primary somatosensory cortex

Carlos A. Sanchez-Leon et al.

Summary: Research has shown that transcranial direct-current stimulation (tDCS) has immediate and lasting effects on sensory processing, with asymmetrical effects induced by anodal and cathodal stimulation.

SCIENTIFIC REPORTS (2021)

Review Clinical Neurology

Neurobiological After-Effects of Low Intensity Transcranial Electric Stimulation of the Human Nervous System: From Basic Mechanisms to Metaplasticity

Sohaib Ali Korai et al.

Summary: This review focuses on the molecular and cellular mechanisms of transcranial direct and alternating current stimulation, highlighting changes in membrane potential, neural synchronization, protein synthesis, and the role of glial cells in synaptic plasticity. Research from in vitro and in vivo studies in animals and humans provide insights into possible pathways for the development of targeted therapeutic applications.

FRONTIERS IN NEUROLOGY (2021)

Article Clinical Neurology

Translating Functional Connectivity After Stroke Functional Magnetic Resonance Imaging Detects Comparable Network Changes in Mice and Humans

Stefan J. Blaschke et al.

Summary: The study showed that network parameters computed for both mouse models of stroke and humans follow a similar pattern in the postacute stroke phase. Parameters indicating the global communication structure's facilitation, such as small worldness and characteristic path length, were similarly changed in humans and mice in the first days after stroke. Additionally, small worldness correlated with concurrent motor impairment in humans and a negative correlation between initial small worldness and motor recovery was observed in mice during the subacute phase.

STROKE (2021)

Article Multidisciplinary Sciences

Traumatic Brain Injury Severity in a Network Perspective: A Diffusion MRI Based Connectome Study

Reut Raizman et al.

Scientific Reports (2020)

Article Clinical Neurology

Predicting the Response to Non-invasive Brain Stimulation in Stroke

Smadar Ovadia-Caro et al.

FRONTIERS IN NEUROLOGY (2019)

Article Mathematical & Computational Biology

Processing Pipeline for Atlas-Based Imaging Data Analysis of Structural and Functional Mouse Brain MRI (AIDAmri)

Niklas Pallast et al.

FRONTIERS IN NEUROINFORMATICS (2019)

Article Neurosciences

Transcranial Current Stimulation Alters the Expression of Immune-Mediating Genes

Monika Rabenstein et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2019)

Article Multidisciplinary Sciences

Post-stroke kinematic analysis in rats reveals similar reaching abnormalities as humans

Gustavo Balbinot et al.

SCIENTIFIC REPORTS (2018)

Article Neurosciences

The global signal in fMRI: Nuisance or Information?

Thomas T. Liu et al.

NEUROIMAGE (2017)

Article Clinical Neurology

Small-World Characteristics of Cortical Connectivity Changes in Acute Stroke

Pietro Caliandro et al.

NEUROREHABILITATION AND NEURAL REPAIR (2017)

Article Veterinary Sciences

Transcranial direct current stimulation in the male mouse to promote recovery after stroke

Anton Pikhovych et al.

LABORATORY ANIMALS (2016)

Article Cell & Tissue Engineering

Transcranial Direct Current Stimulation Modulates Neurogenesis and Microglia Activation in the Mouse Brain

Anton Pikhovych et al.

STEM CELLS INTERNATIONAL (2016)

Review Clinical Neurology

Connectivity-based approaches in stroke and recovery of function

Christian Grefkes et al.

LANCET NEUROLOGY (2014)

Review Clinical Neurology

Physiological Basis of Transcranial Direct Current Stimulation

Charlotte J. Stagg et al.

NEUROSCIENTIST (2011)

Review Clinical Neurology

Exploring the brain network: A review on resting-state fMRI functional connectivity

Martijn P. van den Heuvel et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2010)