4.3 Article

Contrast-enhanced ultrasound evaluation of the utero-placental perfusion in ewes

Journal

SMALL RUMINANT RESEARCH
Volume 228, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.smallrumres.2023.107113

Keywords

Ultrasound; Pregnancy; Sheep; Microbubbles

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This study emphasizes the significance of blood circulation between mother and fetus for a healthy pregnancy and lamb development. The use of contrast-enhanced ultrasound technology provides valuable insights into the blood flow patterns and developmental changes during pregnancy.
This study highlights the importance of blood circulation between mother and fetus for a healthy pregnancy and optimal lamb development. It addresses the challenges of studying blood flow in the utero-placental complex due to small vessel diameters and slow flow. To overcome these, the study utilized contrast-enhanced ultrasound technology (CEUS), which proved to be a safe and effective method for assessing blood flow in the uterus and placentomes of ewes. It reveals a distinct centrifugal and homogeneous perfusion pattern in the uterus and a homogeneous and centripetal pattern in placentomes, with no enhancement detected in the embryos or fetuses. The results, including Doppler and CEUS parameters, provide valuable insights into blood circulation during pregnancy and its developmental changes. It contributes to a better understanding of normal embryonic/fetal development in ewes throughout gestation.

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