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Mediterranean diet and olive oil, microbiota, and obesity-related cancers. From mechanisms to prevention

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Hung N. Luu et al.

Summary: The study found that higher quality diet index (QDI) scores, including the Alternative Health Eating Index-2010 (AHEI-2010), the alternate Mediterranean Diet (aMED), and the Dietary Approaches to Stop Hypertension (DASH), were significantly associated with a lower risk of pancreatic cancer in Asian populations. These results suggest that adherence to a healthy diet may play a role in reducing the risk of pancreatic cancer.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2021)

Review Pathology

Molecular Functions of Hydrogen Sulfide in Cancer

Rodney E. Shackelford et al.

Summary: Hydrogen sulfide plays a complex role in various human malignancies, promoting multiple cancer-related processes and impacting prognosis. Investigating the function of H2S in cancer is crucial for understanding its molecular mechanisms and intervening in cancer development.

PATHOPHYSIOLOGY (2021)

Review Gastroenterology & Hepatology

The interplay between Helicobacter pylori and gastrointestinal microbiota

Chieh-Chang Chen et al.

Summary: The complex population of microbes in the human gastrointestinal tract interacts with the host and itself, influencing health and disease development. Helicobacter pylori colonization affects the gastric microenvironment, thus impacting gastric and potentially colonic microbiota. Understanding how H. pylori shapes GI microbiota and the effects of eradication therapy on colonic microbiota are important areas of research.

GUT MICROBES (2021)

Article Gastroenterology & Hepatology

Mucin degrader Akkermansia muciniphila accelerates intestinal stem cell-mediated epithelial development

Seungil Kim et al.

Summary: Mucin-degrading bacteria, such as A. muciniphila, can promote the proliferation of intestinal stem cells and differentiation of specific cell types in the small intestine and colon. Additionally, treatment with A. muciniphila leads to higher levels of acetic and propionic acids in the cecal contents of mice. Furthermore, pre-treatment with A. muciniphila can reduce gut damage caused by radiation and methotrexate, suggesting a potential role in intestinal homeostasis maintenance.

GUT MICROBES (2021)

Review Public, Environmental & Occupational Health

Association between gallstones and the risk of biliary tract cancer: a systematic review and meta-analysis

Dan Huang et al.

Summary: The presence, size, and number of gallstones are associated with an increased risk of biliary tract cancers, although high heterogeneity is a limitation of the study.

EPIDEMIOLOGY AND HEALTH (2021)

Review Medicine, Research & Experimental

High fat diet, gut microbiome and gastrointestinal cancer

Yao Tong et al.

Summary: Gastrointestinal cancer is a major cause of cancer-related deaths, with a high fat diet and gut microbiome imbalance potentially driving its occurrence and progression through inflammation and changes in the immune environment.

THERANOSTICS (2021)

Article Oncology

Quality diet indexes and risk of hepatocellular carcinoma: Findings from the Singapore Chinese Health Study

Hung N. Luu et al.

Summary: The study found that individuals with higher dietary quality were at lower risk of developing hepatocellular carcinoma (HCC), especially those with higher scores in AHEI-2010, aMED, and DASH. This inverse association was also observed in HBsAg-negative individuals.

INTERNATIONAL JOURNAL OF CANCER (2021)

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Index-based dietary patterns in relation to gastric cancer risk: a systematic review and meta-analysis

Shihao Du et al.

BRITISH JOURNAL OF NUTRITION (2020)

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Diet and the Human Gut Microbiome: An International Review

Annette S. Wilson et al.

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The holobiont concept before Margulis

Jan Baedke et al.

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Association between Mediterranean diet adherence and colorectal cancer: a dose-response meta-analysis

Yuan Zhong et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2020)

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Profile of the gut microbiota of adults with obesity: a systematic review

Louise Crovesy et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2020)

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Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes

Federica Zatterale et al.

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The human tumor microbiome is composed of tumor type-specific intracellular bacteria

Deborah Nejman et al.

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Gregory D. Poore et al.

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Paul Weihe et al.

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Christina Tsigalou et al.

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Glycemic Status, Insulin Resistance, and Risk of Pancreatic Cancer Mortality in Individuals With and Without Diabetes

Nam Hee Kim et al.

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Short-chain fatty acids production by Bifidobacterium species in the presence of salep

Buse Usta-Gorgun et al.

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The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics

Kelly S. Swanson et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

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The role of the Mediterranean diet on weight loss and obesity-related diseases

Ramon Estruch et al.

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The Intestinal Microbiota and Colorectal Cancer

Yiwen Cheng et al.

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Gut microbiota and metabolic health among overweight and obese individuals

Mi-Hyun Kim et al.

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Obesity, estrogens and adipose tissue dysfunction - implications for pulmonary arterial hypertension

Kirsty M. Mair et al.

PULMONARY CIRCULATION (2020)

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You are what you eat: diet, health and the gut microbiota

Niv Zmora et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

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La relación bidireccional entre el cáncer y la ateroesclerosis

Sergio Raposeiras Roubín et al.

REVISTA ESPANOLA DE CARDIOLOGIA (2019)

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Estrogens and breast cancer: Mechanisms involved in obesity-related development, growth and progression

Priya Bhardwaj et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2019)

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Circulating adipokines and risk of obesity related cancers: A systematic review and meta-analysis

Yeong Sook Yoon et al.

OBESITY RESEARCH & CLINICAL PRACTICE (2019)

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Impact of different types of olive oil on cardiovascular risk factors: A systematic review and network meta-analysis

Lukas Schwingshackl et al.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2019)

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Gut Microbiota Shapes the Efficiency of Cancer Therapy

Weidong Ma et al.

FRONTIERS IN MICROBIOLOGY (2019)

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Baseline human gut microbiota profile in healthy people and standard reporting template

Charles H. King et al.

PLOS ONE (2019)

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Food Components and Dietary Habits: Keys for a Healthy Gut Microbiota Composition

Emanuele Rinninella et al.

NUTRIENTS (2019)

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Cancer and Mediterranean Diet: A Review

Maria Chiara Mentella et al.

NUTRIENTS (2019)

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Relevance of Leptin and Other Adipokines in Obesity-Associated Cardiovascular Risk

Manuel F. Landecho et al.

NUTRIENTS (2019)

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Microbiota and gastrointestinal cancer

Meng-Tzu Weng et al.

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2019)

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Childhood obesity: increased risk for cardiometabolic disease and cancer in adulthood

Susann Weihrauch-Blueher et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2019)

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Obesity and cancer risk: Emerging biological mechanisms and perspectives

Konstantinos Avgerinos et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2019)

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The Unexplored World of Human Virome, Mycobiome, and Archaeome in Aging

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JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2019)

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Emerging cancer trends among young adults in the USA: analysis of a population-based cancer registry

Hyuna Sung et al.

LANCET PUBLIC HEALTH (2019)

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Serum glucose and insulin and risk of cancers of the breast, endometrium, and ovary in postmenopausal women

Geoffrey C. Kabat et al.

EUROPEAN JOURNAL OF CANCER PREVENTION (2018)

Review Public, Environmental & Occupational Health

Evaluating Mediterranean diet and risk of chronic disease in cohort studies: an umbrella review of meta-analyses

Cecilia Galbete et al.

EUROPEAN JOURNAL OF EPIDEMIOLOGY (2018)

Editorial Material Immunology

Collaborating centres: Rediscovering an extended arm of World Health Organization

Poonam Khetrapal Singh

INDIAN JOURNAL OF MEDICAL RESEARCH (2018)

Article Nutrition & Dietetics

Colonic Mucosal Bacteria Are Associated with Inter-Individual Variability in Serum Carotenoid Concentrations

Zora Djuric et al.

JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS (2018)

Article Multidisciplinary Sciences

Environment dominates over host genetics in shaping human gut microbiota

Daphna Rothschild et al.

NATURE (2018)

Article Oncology

Adherence to Mediterranean diet and the risk of breast cancer: a meta-analysis

Yao Li et al.

TRANSLATIONAL CANCER RESEARCH (2018)

Article Nutrition & Dietetics

Effect of virgin olive oil and thyme phenolic compounds on blood lipid profile: implications of human gut microbiota

Sandra Martin-Pelaez et al.

EUROPEAN JOURNAL OF NUTRITION (2017)

Review Nutrition & Dietetics

Mediterranean diet and colorectal cancer: A systematic review

Alberto Farinetti et al.

NUTRITION (2017)

Review Oncology

Rethinking the bile acid/gut microbiome axis in cancer

John P. Phelan et al.

ONCOTARGET (2017)

Review Urology & Nephrology

The interplay of extracellular matrix and microbiome in urothelial bladder cancer

Massimo Alfano et al.

NATURE REVIEWS UROLOGY (2016)

Review Pathology

Obesity, Inflammation, and Cancer

Tuo Deng et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 11 (2016)

Article Gastroenterology & Hepatology

Current Understanding of Dysbiosis in Disease in Human and Animal Models

Arianna K. DeGruttola et al.

INFLAMMATORY BOWEL DISEASES (2016)

Article Endocrinology & Metabolism

Two Healthy Diets Modulate Gut Microbial Community Improving Insulin Sensitivity in a Human Obese Population

Carmen Haro et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

Article Medicine, General & Internal

Body Fatness and Cancer - Viewpoint of the IARC Working Group

Beatrice Lauby-Secretan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Multidisciplinary Sciences

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

Alexandra Zhernakova et al.

SCIENCE (2016)

Article Nutrition & Dietetics

Influence of Phenol-Enriched Olive Oils on Human Intestinal Immune Function

Sandra Martin-Pelaez et al.

NUTRIENTS (2016)

Article Biochemistry & Molecular Biology

Revised Estimates for the Number of Human and Bacteria Cells in the Body

Ron Sender et al.

PLOS BIOLOGY (2016)

Review Immunology

The Macrophage Switch in Obesity Development

Angela Castoldi et al.

FRONTIERS IN IMMUNOLOGY (2016)

Review Medicine, Research & Experimental

Obesity and Cancer: Local and Systemic Mechanisms

Neil M. Iyengar et al.

ANNUAL REVIEW OF MEDICINE, VOL 66 (2015)

Article Oncology

Dietary Microbes Modulate Transgenerational Cancer Risk

Theofilos Poutahidis et al.

CANCER RESEARCH (2015)

Review Oncology

Body fatness as a cause of cancer: epidemiologic clues to biologic mechanisms

Tim Byers et al.

ENDOCRINE-RELATED CANCER (2015)

Review Biochemistry & Molecular Biology

Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer

Xuyi Wang et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)

Article Oncology

Inflammation and cancer: advances and new agents

Shanthini M. Crusz et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2015)

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Weight Gain After Fecal Microbiota Transplantation

Neha Alang et al.

OPEN FORUM INFECTIOUS DISEASES (2015)

Review Oncology

Adiposity and cancer risk: new mechanistic insights from epidemiology

Andrew G. Renehan et al.

NATURE REVIEWS CANCER (2015)

Article Oncology

Role of Hyperinsulinemia in Increased Risk of Prostate Cancer: A Case Control Study from Kathmandu Valley

Dipendra Raj Pandeya et al.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2014)

Article Gastroenterology & Hepatology

Obesity and the risk and prognosis of gallstone disease and pancreatitis

Leonilde Bonfrate et al.

BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY (2014)

Article Hematology

Body size and multiple myeloma mortality: a pooled analysis of 20 prospective studies

Lauren R. Teras et al.

BRITISH JOURNAL OF HAEMATOLOGY (2014)

Review Oncology

The Microbiome and Obesity-An Established Risk for Certain Types of Cancer

Connie J. Rogers et al.

CANCER JOURNAL (2014)

Article Oncology

Anthropometric and Hormonal Risk Factors for Male Breast Cancer: Male Breast Cancer Pooling Project Results

Louise A. Brinton et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)

Review Medicine, General & Internal

Barrett's Esophagus

Stuart J. Spechler et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Multidisciplinary Sciences

In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation

Soracha Thamphiwatana et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Medicine, General & Internal

The link between obesity and cancer

Cesar Sanchez R et al.

REVISTA MEDICA DE CHILE (2014)

Review Public, Environmental & Occupational Health

Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score

Francesco Sofi et al.

PUBLIC HEALTH NUTRITION (2014)

Article Gastroenterology & Hepatology

Possible roles of insulin, IGF-1 and IGFBPs in initiation and progression of colorectal cancer

Bo Jiang et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Reproductive Biology

A prospective cohort study of dietary indices and incidence of epithelial ovarian cancer

Jing Xie et al.

JOURNAL OF OVARIAN RESEARCH (2014)

Review Medicine, Research & Experimental

Cytokines, Obesity, and Cancer: New Insights on Mechanisms Linking Obesity to Cancer Risk and Progression

Candace A. Gilbert et al.

ANNUAL REVIEW OF MEDICINE, VOL 64 (2013)

Review Biochemistry & Molecular Biology

Mechanisms linking obesity and cancer

Sharon M. Louie et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)

Review Biochemistry & Molecular Biology

Origins and Actions of Tumor Necrosis Factor α in Postmenopausal Breast Cancer

Sarah Q. To et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2013)

Article Multidisciplinary Sciences

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

Bo Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

Vanessa K. Ridaura et al.

SCIENCE (2013)

Article Gastroenterology & Hepatology

Gastro-esophageal reflux disease and obesity, where is the link?

Sara Emerenziani et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2013)

Review Oncology

The microbiome and cancer

Robert F. Schwabe et al.

NATURE REVIEWS CANCER (2013)

Article Endocrinology & Metabolism

Insulin resistance/hyperinsulinemia and cancer mortality: the Cremona study at the 15th year of follow-up

Gianluca Perseghin et al.

ACTA DIABETOLOGICA (2012)

Review Nutrition & Dietetics

Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia

Ana Paula Boroni Moreira et al.

BRITISH JOURNAL OF NUTRITION (2012)

Review Oncology

Obesity, Energy Balance, and Cancer: New Opportunities for Prevention

Stephen D. Hursting et al.

CANCER PREVENTION RESEARCH (2012)

Review Endocrinology & Metabolism

The Role of Adiponectin in Cancer: A Review of Current Evidence

Maria Dalamaga et al.

ENDOCRINE REVIEWS (2012)

Article Biochemistry & Molecular Biology

Palmitoleate Is a Mitogen, Formed upon Stimulation with Growth Factors, and Converted to Palmitoleoyl-phosphatidylinositol

Andreas Koeberle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Medicine, Research & Experimental

Antibacterial Activities of Liposomal Linolenic Acids against Antibiotic-Resistant Helicobacter pylori

Marygorret Obonyo et al.

MOLECULAR PHARMACEUTICS (2012)

Article Multidisciplinary Sciences

Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower et al.

NATURE (2012)

Article Multidisciplinary Sciences

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

Janelle C. Arthur et al.

SCIENCE (2012)

Article Endocrinology & Metabolism

Regulation of adiponectin production by insulin: interactions with tumor necrosis factor-α and interleukin-6

Tahar Hajri et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)

Review Microbiology

Microbiome and Malignancy

Claudia S. Plottel et al.

CELL HOST & MICROBE (2011)

Review Gastroenterology & Hepatology

Influence of obesity on the risk of esophageal disorders

Jesper Lagergren

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)

Article Public, Environmental & Occupational Health

Mediterranean diet pyramid today. Science and cultural updates

Anna Bach-Faig et al.

PUBLIC HEALTH NUTRITION (2011)

Article Gastroenterology & Hepatology

Meta-analysis: the association of oesophageal adenocarcinoma with symptoms of gastro-oesophageal reflux

J. H. Rubenstein et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2010)

Article Oncology

Incident cancer burden attributable to excess body mass index in 30 European countries

Andrew G. Renehan et al.

INTERNATIONAL JOURNAL OF CANCER (2010)

Review Cell Biology

Chronic Inflammation in Obesity and the Metabolic Syndrome

Rosario Monteiro et al.

MEDIATORS OF INFLAMMATION (2010)

Review Endocrinology & Metabolism

IGF-I, insulin and prostate cancer

Giovanna A. Balarini Lima et al.

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA (2009)

Article Medicine, General & Internal

Adherence to a Mediterranean Diet, Cognitive Decline, and Risk of Dementia

Catherine Feart et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

Article Endocrinology & Metabolism

Effect of Tumor Necrosis Factor-alpha on Estrogen Metabolism and Endometrial Cells: Potential Physiological and Pathological Relevance

Salama A. Salama et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)

Article Oncology

A prospective evaluation of insulin and insulin-like growth factor-I as risk factors for endometrial cancer

Marc J. Gunter et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)

Article Medicine, Research & Experimental

Cholesterol gallstones and cancer of gallbladder (CAGB): molecular links

Ajit Venniyoor

MEDICAL HYPOTHESES (2008)

Article Agriculture, Multidisciplinary

How heating affects extra virgin olive oil quality indexes and chemical composition

Yosra Allouche et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)

Article Oncology

Chronic inflammation and bladder cancer

Dominique S. Michaud

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2007)

Review Pharmacology & Pharmacy

The role of insulin receptor isoforms and hybrid Insulin/IGF-I receptors in human cancer

Antonino Belfiore

CURRENT PHARMACEUTICAL DESIGN (2007)

Article Clinical Neurology

Mediterranean diet and risk for Alzheimer's disease

Nikolaos Scarmeas et al.

ANNALS OF NEUROLOGY (2006)

Review Endocrinology & Metabolism

The role of TNF-α in insulin resistance

SE Borst

ENDOCRINE (2004)

Review Immunology

The chemokine system in diverse forms of macrophage activation and polarization

A Mantovani et al.

TRENDS IN IMMUNOLOGY (2004)

Article Public, Environmental & Occupational Health

Traditional Mediterranean diet and longevity in the elderly: a review

A Trichopoulou

PUBLIC HEALTH NUTRITION (2004)

Article Oncology

Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women

TJ Key et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)

Article Medicine, General & Internal

Adherence to a Mediterranean diet and survival in a Greek population

A Trichopoulou et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

Article Medicine, Research & Experimental

Obesity is associated with macrophage accumulation in adipose tissue

SP Weisberg et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)

Article Oncology

Olive oil, seed oils and other added fats in relation to ovarian cancer (Italy)

C Bosetti et al.

CANCER CAUSES & CONTROL (2002)