Journal
RUSSIAN CHEMICAL BULLETIN
Volume 72, Issue 8, Pages 1760-1766Publisher
SPRINGER
DOI: 10.1007/s11172-023-3958-z
Keywords
Crataegus oresbia; Rosaceae; chemical constituents; triterpenoids; cytotoxicity
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A new ursane triterpenoid caffeic acid ester, cratoresbate A, along with seven known ursane triterpenoids, was isolated from the twigs and leaves of Crataegus oresbia W. W. Sm. Cratoresbate A exhibited significant cytotoxicity against HepG2 cells with an IC50 value of 1.9 μmol L-1.
A new ursane triterpenoid caffeic acid ester, cratoresbate A, together with seven known ursane triterpenoids (3-O-trans-p-coumaroyltormentic acid, 3-O-cis-p-coumaroyltormentic acid, alpha-amyrin, ursolic acid, pomolic acid, euscaphic acid, and tormentic acid) were isolated from the twigs and leaves of Crataegus oresbia W. W. Sm. Cratoresbate A showed significant cytotoxicity against HepG2 cells with IC50 value of 1.9 mu mol L-1.
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