4.5 Article

Estrogen Regulates Scribble Localization in Endometrial Epithelial Cells Through Acyl Protein Thioesterase (APT)-Mediated S-Palmitoylation in Adenomyosis

Related references

Note: Only part of the references are listed.
Article Obstetrics & Gynecology

Scribble downregulation in adenomyosis compromises endometrial stromal decidualization by decreasing FOXO1 expression

Yaoming Peng et al.

Summary: SCRIB knockdown impairs decidualization of endometrial stromal cells by decreasing FOXO1 expression through the AKT and aPKC pathways. Abnormal decidualization in adenomyosis may be linked to infertility and impact embryo implantation. Clinical implications for counseling and treating infertile adenomyosis patients may be significant.

HUMAN REPRODUCTION (2022)

Review Biochemistry & Molecular Biology

Protein S-Palmitoylation: advances and challenges in studying a therapeutically important lipid modification

Alice Main et al.

Summary: This review discusses the role of lipid post-translational modification S-palmitoylation in diseases and the advancements in experimental tools in the field. Understanding how palmitoylation controls protein localization and function may lead to its modulation as a therapeutic strategy in the future.

FEBS JOURNAL (2022)

Review Cell Biology

Apical-basal polarity and the control of epithelial form and function

Clare E. Buckley et al.

Summary: Apical-basal polarity is crucial for the form and function of epithelial cells, determining cell adhesion, barrier function, specific cargo secretion, and cytoskeletal organization. Conserved polarity factors play important roles in establishing and maintaining apical-basal polarity, although different mechanisms may be involved in different epithelial tissues.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2022)

Review Reproductive Biology

Conservative surgical and drug therapies for adenomyosis Medicine

Yiyue Fan et al.

Summary: This study summarizes the treatment options for adenomyosis, including both conservative and surgical methods. Conservative treatment is important for patients with fertility requirements or a strong desire to retain the uterus.

REPRODUCTIVE BIOLOGY (2022)

Article Reproductive Biology

Impaired decidualization of human endometrial stromal cells from women with adenomyosis

Yaoming Peng et al.

Summary: The endometrial stromal cells of adenomyosis exhibit a defective ability for full decidualization, which may result in a nonreceptive endometrium. Changes in the secretion of cytokines and matrix metalloproteinases were also observed, indicating an aberrant decidualization response in adenomyosis.

BIOLOGY OF REPRODUCTION (2021)

Article Obstetrics & Gynecology

Adenomyosis pathogenesis: insights from next-generation sequencing

Serdar E. Bulun et al.

Summary: Adenomyosis is a challenging uterine disorder with unclear origins, involving contributions from abnormal endometrial tissue and smooth muscle cells. Recent studies suggest a link between adenomyosis and endometriosis in terms of cell origins, indicating both diseases arise from endometrial cell populations carrying specific driver mutations.

HUMAN REPRODUCTION UPDATE (2021)

Review Medicine, General & Internal

Current and Prospective Treatment of Adenomyosis

Fady I. Sharara et al.

Summary: Adenomyosis is a complex disease with various treatment options available. This paper reviews the current medical and surgical treatments for adenomyosis and emphasizes the need for further research to establish a standardized treatment algorithm through randomized controlled trials.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Cell Biology

Scribble: A master scaffold in polarity, adhesion, synaptogenesis, and proliferation

Teresa T. Bonello et al.

JOURNAL OF CELL BIOLOGY (2019)

Review Obstetrics & Gynecology

Uterine adenomyosis and adenomyoma: the surgical approach

Hisao Osada

FERTILITY AND STERILITY (2018)

Review Biochemistry & Molecular Biology

Protein depalmitoylases

Sang Joon Won et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2018)

Article Multidisciplinary Sciences

Palmitoylation-dependent activation of MC1R prevents melanomagenesis

Shuyang Chen et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells

Jeannie L. Hernandez et al.

CELL CHEMICAL BIOLOGY (2017)

Article Biochemistry & Molecular Biology

ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity

Baoen Chen et al.

NATURE CHEMICAL BIOLOGY (2016)

Review Pharmacology & Pharmacy

The Important Roles of Steroid Sulfatase and Sulfotransferases in Gynecological Diseases

Tea Lanisnik Rizner

FRONTIERS IN PHARMACOLOGY (2016)

Article Biochemistry & Molecular Biology

Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases

Armand B. Cognetta et al.

CHEMISTRY & BIOLOGY (2015)

Article Anatomy & Morphology

Localization, Not Important in All Tumor-Suppressing Properties: A Lesson Learnt from Scribble

Imogen A. Elsum et al.

CELLS TISSUES ORGANS (2013)

Review Biochemistry & Molecular Biology

What does S-palmitoylation do to membrane proteins?

Sanja Blaskovic et al.

FEBS JOURNAL (2013)

Review Oncology

Cell polarity proteins and cancer

Saskia I. J. Ellenbroek et al.

SEMINARS IN CANCER BIOLOGY (2012)

Article Medicine, Research & Experimental

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

Helen B. Pearson et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Biochemistry & Molecular Biology

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

Alexander Adibekian et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Small-molecule inhibition of APT1 affects Ras localization and signaling

Frank J. Dekker et al.

NATURE CHEMICAL BIOLOGY (2010)