Journal
MONATSHEFTE FUR CHEMIE
Volume 147, Issue 11, Pages 2001-2008Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-016-1700-3
Keywords
T3P (R); Amide; DPPH; Antimicrobial; Antioxidant; Chelating activity
Categories
Funding
- Department of Science and Technology, New Delhi, India [IF130464]
Ask authors/readers for more resources
In the present study, a series of amide derivatives of 4-nitro-l-phenylalanine were synthesized with good yield from 4-nitro-l-phenylalanine and substituted anilines using propylphosphonic anhydride (T3P(A (R))) as coupling reagent and were characterized through the IR, LC-MS, H-1 and C-13 NMR spectral studies. The isolated products were screened for antimicrobial and antioxidant activities. Some of the compounds showed Microsporum gypsuem activity or were active against Candida albicans, also a few of compounds showed antibacterial activities. The resultant compounds screened for anti-oxidant activity, which showed good activity for DPPH scavenging and ABTS assay methods and others had moderately activity. Some amide compounds act as metal chelating ligands with Fe2+ ions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available