4.6 Review

Azidation in the Difunctionalization of Olefins

Journal

MOLECULES
Volume 21, Issue 3, Pages -

Publisher

MDPI
DOI: 10.3390/molecules21030352

Keywords

azides; difunctionalization; olefins

Funding

  1. National Basic Research Program of China (973 Program) [2015CB856600]
  2. National Natural Science Foundation of China [21325206, 21172006]
  3. National Young Top-notch Talent Support Program

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Organic azides are key motifs in compounds of relevance to chemical biology, medicinal chemistry and materials science. In addition, they also serve as useful building blocks due to their remarkable reactivity. Therefore, the development of efficient protocols to synthesize these compounds is of great significance. This paper reviews the major applications and development of azidation in difunctionalization of olefins using azide reagents.

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