4.6 Review

Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells

Keiichi Motoyama et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2016)

Article Chemistry, Medicinal

Back to the Future: A New Look at Hydroxypropyl Beta-Cyclodextrins

Milo Malanga et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

Article Cell Biology

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

Sebastian Zimmer et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Chemistry, Medicinal

Formulation, optimization, and pharmacodynamic evaluation of chitosan/phospholipid/β-cyclodextrin microspheres

Lu Shan et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2016)

Article Clinical Neurology

Efficacy and ototoxicity of different cyclodextrins in Niemann-Pick C disease

Cristin D. Davidson et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2016)

Article Pharmacology & Pharmacy

Intranasal delivery of dopamine to the striatum using glycol chitosan/sulfobutylether-β-cyclodextrin based nanoparticles

Sante Di Gioia et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)

Article Chemistry, Medicinal

Molecular Dynamics Simulations of the Interaction of Beta Cyclodextrin with a Lipid Bilayer

Wasinee Khuntawee et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2015)

Article Multidisciplinary Sciences

Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein

Kiri Kilpatrick et al.

PLOS ONE (2015)

Article Pharmacology & Pharmacy

Masking the Bitter Taste of Injectable Lidocaine HCl Formulation for Dental Procedures

Yangjie Wei et al.

AAPS PHARMSCITECH (2015)

Article Endocrinology & Metabolism

Complex lipid trafficking in Niemann-Pick disease type C

Marie T. Vanier

JOURNAL OF INHERITED METABOLIC DISEASE (2015)

Article Biochemistry & Molecular Biology

Effects of oxysterols on the blood-brain barrier: Implications for Alzheimer's disease

Fabien Gosselet et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Biotechnology & Applied Microbiology

Cholesterol depletion induces transcriptional changes during skeletal muscle differentiation

Ana C. B. Possidonio et al.

BMC GENOMICS (2014)

Article Pharmacology & Pharmacy

Human ABC Transporters at blood-CNS Interfaces as Determinants of CNS Drug Penetration

Catarina Chaves et al.

CURRENT PHARMACEUTICAL DESIGN (2014)

Review Biochemistry & Molecular Biology

Molecular Mechanisms of Cellular Cholesterol Efflux

Michael C. Phillips

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Anesthesiology

Three suspected cases of sugammadex-induced anaphylactic shock

Tomonori Takazawa et al.

BMC ANESTHESIOLOGY (2014)

Article Clinical Neurology

Amyloid-β Peptides, Alzheimer's Disease and the Blood-brain Barrier

Fabien Gosselet et al.

CURRENT ALZHEIMER RESEARCH (2013)

Review Chemistry, Medicinal

Liver X receptor modulators: a review of recently patented compounds (2009-2012)

Jon Loren et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2013)

Article Medicine, Research & Experimental

Self-assembling Modified β-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease

Bruno M. D. C. Godinho et al.

MOLECULAR PHARMACEUTICS (2013)

Article Multidisciplinary Sciences

Computational microscopy of cyclodextrin mediated cholesterol extraction from lipid model membranes

Cesar A. Lopez et al.

SCIENTIFIC REPORTS (2013)

Article Biochemistry & Molecular Biology

β-Cyclodextrin-poly(β-Amino Ester) Nanoparticles for Sustained Drug Delivery across the Blood-Brain Barrier

Eun Seok Gil et al.

BIOMACROMOLECULES (2012)

Article Anesthesiology

Three cases of suspected sugammadex-induced hypersensitivity reactions

K. Godai et al.

BRITISH JOURNAL OF ANAESTHESIA (2012)

Article Immunology

Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease

Jiaqi Yao et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

Article Pharmacology & Pharmacy

Albumin nanoparticles carrying cyclodextrins for nasal delivery of the anti-Alzheimer drug tacrine

Barbara Luppi et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2011)

Article Peripheral Vascular Disease

Distribution of Smooth Muscle Cells and Macrophages Expressing Scavenger Receptor BI/II in Atherosclerosis

Yukio Ishikawa et al.

Journal of Atherosclerosis and Thrombosis (2011)

Article Multidisciplinary Sciences

TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre et al.

SCIENCE (2011)

Article Cell Biology

Alzheimer's Disease

Dennis J. Selkoe

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Article Biochemical Research Methods

Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction

Cesar A. Lopez et al.

PLOS COMPUTATIONAL BIOLOGY (2011)

Article Pharmacology & Pharmacy

Evaluation of the cytotoxicity of β-cyclodextrin derivatives: Evidence for the role of cholesterol extraction

T. Kiss et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Article Medicine, Research & Experimental

LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression

Jonathan E. Feig et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease

Daniel del Toro et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Review Genetics & Heredity

Niemann-Pick disease type C

Marie T. Vanier

ORPHANET JOURNAL OF RARE DISEASES (2010)

Article Multidisciplinary Sciences

Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells

Anton I. Rosenbaum et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Cardiac & Cardiovascular Systems

Cholesterol Homeostasis and High-Density Lipoprotein Formation in Arterial Smooth Muscle Cells

Sima Allahverdian et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2010)

Article Pharmacology & Pharmacy

Pharmacokinetic evaluation and modeling of formulated levodopa intranasal delivery systems

Tae Kyung Kim et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2009)

Article Pharmacology & Pharmacy

Mucoadhesive microspheres for nasal administration of cyclodextrins

Elisabetta Gavini et al.

JOURNAL OF DRUG TARGETING (2009)

Article Multidisciplinary Sciences

Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

Benny Liu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

A Gene Network Regulating Lysosomal Biogenesis and Function

Marco Sardiello et al.

SCIENCE (2009)

Review Biochemistry & Molecular Biology

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

Woojin Scott Kim et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Structure-activity relationships of amyloid beta-aggregation inhibitors based on curcumin: Influence of linker length and flexibility

Ashley A. Reinke et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2007)

Article Pharmacology & Pharmacy

Cyclodextrins and their pharmaceutical applications

Thorsteinn Loftsson et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

Review Neurosciences

Cholesterol dysfunction in neurodegenerative diseases: Is Huntington's disease in the list?

Marta Valenza et al.

PROGRESS IN NEUROBIOLOGY (2006)

Article Multidisciplinary Sciences

Pregnane X receptor (PXR) activation: A mechanism for neuroprotection in a mouse model of Niemann-Pick C disease

S. Joshua Langmade et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Effects of the cholesterol-lowering compound methyl-β-cyclodextrin in models of α-synucleinopathy

Pazit Bar-On et al.

JOURNAL OF NEUROCHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Small molecule inhibitors of α-synuclein filament assembly

Masami Masuda et al.

BIOCHEMISTRY (2006)

Article Hematology

ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I

IC Gelissen et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)

Review Clinical Neurology

Microglia in the aging brain

Jessica R. Conde et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)

Article Biochemistry & Molecular Biology

Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

R Koldamova et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Food Science & Technology

2-hydroxypropyl-β-cyclodextrin (HP-β-CD):: A toxicology review

S Gould et al.

FOOD AND CHEMICAL TOXICOLOGY (2005)

Article Medicine, Research & Experimental

Alzheimer disease β-amyloid activity mimics cholesterol oxidase

L Puglielli et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Article Biochemistry & Molecular Biology

The liver X receptor ligand T0901317 decreases amyloid β production in vitro and in a mouse model of Alzheimer's disease

T Koldamova et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Neurosciences

Cholesterol and the biology of Alzheimer's disease

B Wolozin

NEURON (2004)

Article Pharmacology & Pharmacy

Behavior of α-, β-, and γ-cyclodextrins and their derivatives on an in vitro model of blood-brain barrier

V Monnaert et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Article Pharmacology & Pharmacy

Effects of γ- and hydroxypropyl-γ-cyclodextrins on the transport of doxorubicin across an in vitro model of blood-brain barrier

V Monnaert et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Article Clinical Neurology

ABCA1 expression in carotid atherosclerotic plaques

C Albrecht et al.

STROKE (2004)

Review Biotechnology & Applied Microbiology

Cyclodextrin-based pharmaceutics: Past, present and future

ME Davis et al.

NATURE REVIEWS DRUG DISCOVERY (2004)

Article Biochemistry & Molecular Biology

Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

LD Griffin et al.

NATURE MEDICINE (2004)

Article Biochemistry & Molecular Biology

Cyclodextrins differentially mobilize free and esterified cholesterol from primary human foam cell macrophages

SM Liu et al.

JOURNAL OF LIPID RESEARCH (2003)

Article Medicine, General & Internal

Plasma total cholesterol level as a risk factor for Alzheimer disease - The Framingham study

ZS Tan et al.

ARCHIVES OF INTERNAL MEDICINE (2003)

Article Multidisciplinary Sciences

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

E Hockly et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Pharmacology & Pharmacy

Antioxidants as treatment for neurodegenerative disorders

B Moosmann et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2002)

Article Biochemistry & Molecular Biology

Per-6-substituted β-cyclodextrin libraries inhibit formation of β-amyloid-peptide (Aβ)-derived, soluble oligomers

JX Yu et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2002)

Article Multidisciplinary Sciences

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

SB Joseph et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Medicine, Research & Experimental

Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease

F Camargo et al.

LIFE SCIENCES (2001)

Review Neurosciences

Alpha-synuclein and neurodegenerative diseases

M Goedert

NATURE REVIEWS NEUROSCIENCE (2001)

Article Multidisciplinary Sciences

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

K Fassbender et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Cell Biology

Tight junctions of the blood-brain barrier

U Kniesel et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2000)