Journal
MOLECULES
Volume 21, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/molecules21040441
Keywords
pyrazolo[4 ',3 ':5,6]pyrido[2,3-d]pyrimidine-diones; green synthesis; multi-component reaction; in water reaction
Funding
- Iran National Science Foundation (INSF)
- Alzahra University
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A novel one pot synthesis of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-diones, via a five-component reaction, involving, hydrazine hydrate, ethyl acetoacetate, and 1,3-dimethyl barbituric acid, an appropriate aryl aldehydes and ammonium acetate catalyzed via both of heterogeneous and homogeneous catalysis in water, is reported.
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