4.6 Review

Structure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks

Related references

Note: Only part of the references are listed.
Editorial Material Biochemistry & Molecular Biology

Response Surface Optimization for Decaffeination and Theophylline Production by Fusarium solani

Shwetha Nanjundaiah et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2016)

Article Chemistry, Medicinal

Theanine and Caffeine Content of Infusions Prepared from Commercial Tea Samples

Klara Boros et al.

PHARMACOGNOSY MAGAZINE (2016)

Article Biochemistry & Molecular Biology

1,3,7-Triethyl-substituted xanthines-possess nanomolar affinity for the adenosine A1 receptor

Mietha M. Van der Walt et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2015)

Article Neurosciences

Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug?

Simone Cappelletti et al.

CURRENT NEUROPHARMACOLOGY (2015)

Article Pharmacology & Pharmacy

The relevance of theobromine for the beneficial effects of cocoa consumption

Eva Martinez-Pinilla et al.

FRONTIERS IN PHARMACOLOGY (2015)

Article Biochemistry & Molecular Biology

Coupled gating modifies the regulation of cardiac ryanodine receptors by luminal Ca2+

Jana Gaburjakova et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)

Review Nutrition & Dietetics

Tea consumption and risk of type 2 diabetes: a dose-response meta-analysis of cohort studies

Wan-Shui Yang et al.

BRITISH JOURNAL OF NUTRITION (2014)

Article Biochemistry & Molecular Biology

Tadalafil inhibits the cAMP stimulated glucose output in the rat liver

Vanessa Rodrigues Vilela et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2014)

Article Nutrition & Dietetics

Effect of white tea (Camellia sinensis (L.)) extract in the glycolytic profile of Sertoli cell

A. D. Martins et al.

EUROPEAN JOURNAL OF NUTRITION (2014)

Article Geriatrics & Gerontology

Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease

Hui Qi et al.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2014)

Article Agriculture, Multidisciplinary

White Tea as a Promising Antioxidant Medium Additive for Sperm Storage at Room Temperature: A Comparative Study with Green Tea

Tania R. Dias et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)

Article Medicine, Legal

Fatal Caffeine Intoxication: A Series of Eight Cases from 1999 to 2009

Priya Banerjee et al.

JOURNAL OF FORENSIC SCIENCES (2014)

Review Chemistry, Medicinal

The Effects of Caffeine on the Cholinergic System

Miroslav Pohanka

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2014)

Article Gastroenterology & Hepatology

Novel methylxanthine derivative-mediated anti-inflammatory effects in inflammatory bowel disease

In-Ah Lee et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Public, Environmental & Occupational Health

Maternal Caffeine Consumption and Small for Gestational Age Births: Results from a Population-Based Case-Control Study

Adrienne T. Hoyt et al.

MATERNAL AND CHILD HEALTH JOURNAL (2014)

Article Nutrition & Dietetics

Caffeinated and caffeine-free beverages and risk of type 2 diabetes

Shilpa N. Bhupathiraju et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2013)

Article Nutrition & Dietetics

Effect of cocoa and theobromine consumption on serum HDL-cholesterol concentrations: a randomized controlled trial

Nicole Neufingerl et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2013)

Article Critical Care Medicine

Theophylline

Peter J. Barnes

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)

Article Biochemistry & Molecular Biology

Caffeine Inhibits Acetylcholinesterase, But Not Butyrylcholinesterase

Miroslav Pohanka et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Biochemical Research Methods

Development and validation of a rapid ultra high pressure liquid chromatographic method for the determination of methylxanthines in herbal infusions

Constantinos K. Zacharis et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2013)

Article Medicine, Research & Experimental

The interactions of caffeine with monoamine oxidase

Anel Petzer et al.

LIFE SCIENCES (2013)

Article Neurosciences

Association between caffeine intake and age at onset in Huntington's disease

Clemence Simonin et al.

NEUROBIOLOGY OF DISEASE (2013)

Article Neurosciences

Psychopharmacology of theobromine in healthy volunteers

Matthew J. Baggott et al.

PSYCHOPHARMACOLOGY (2013)

Review Dermatology

Caffeine's Mechanisms of Action and Its Cosmetic Use

A. Herman et al.

SKIN PHARMACOLOGY AND PHYSIOLOGY (2013)

Review Nutrition & Dietetics

Health Benefits of Methylxanthines in Cacao and Chocolate

Rafael Franco et al.

NUTRIENTS (2013)

Article Physiology

Caffeine relaxes smooth muscle through actin depolymerization

Tracy Tazzeo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)

Article Developmental Biology

Maternal caffeine consumption and risk of congenital limb deficiencies

Lei Chen et al.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2012)

Article Clinical Neurology

Caffeine and risk of Parkinson's disease in a large cohort of men and women

Natalia Palacios et al.

MOVEMENT DISORDERS (2012)

Article Clinical Neurology

Caffeine for treatment of Parkinson disease A randomized controlled trial

Ronald B. Postuma et al.

NEUROLOGY (2012)

Article Chemistry, Applied

Analytical Techniques Used for Determination of Methylxanthines and their Analogues-Recent Advances

P. Talik et al.

SEPARATION AND PURIFICATION REVIEWS (2012)

Editorial Material Cell Biology

The Cyclic AMP Pathway

Paolo Sassone-Corsi

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Espresso coffees, caffeine and chlorogenic acid intake: potential health implications

Thomas W. M. Crozier et al.

FOOD & FUNCTION (2012)

Review Biochemistry & Molecular Biology

Effects of tea and coffee on cardiovascular disease risk

Siv K. Bohn et al.

FOOD & FUNCTION (2012)

Review Endocrinology & Metabolism

Coffee to Reduce Risk of Type 2 Diabetes? : A Systematic Review

Arti Muley et al.

CURRENT DIABETES REVIEWS (2012)

Article Ophthalmology

Effects of 7-methylxanthine on the sclera in form deprivation myopia in guinea pigs

Dongmei Cui et al.

ACTA OPHTHALMOLOGICA (2011)

Review Public, Environmental & Occupational Health

Coffee Consumption and Risk of Stroke: A Dose-Response Meta-Analysis of Prospective Studies

Susanna C. Larsson et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2011)

Article Developmental Biology

Maternal Caffeine Intake and Risk of Selected Birth Defects in the National Birth Defects Prevention Study

Marilyn L. Browne et al.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2011)

Article Chemistry, Applied

Focused microwaves-assisted extraction of theobromine and caffeine from cacao

Leslie N. Gonzalez-Nunez et al.

FOOD CHEMISTRY (2011)

Article Chemistry, Physical

Is Caffeine a Good Scavenger of Oxygenated Free Radicals?

Jorge Rafael Leon-Carmona et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2011)

Review Veterinary Sciences

The effects of prenatal exposure to methylxanthines

P. Skopinski et al.

POLISH JOURNAL OF VETERINARY SCIENCES (2011)

Article Biochemistry & Molecular Biology

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

Andrew S. Dore et al.

STRUCTURE (2011)

Article Biochemical Research Methods

Caffeine and paraxanthine HPLC assay for CYP1A2 phenotype assessment using saliva and plasma

Vidya Perera et al.

BIOMEDICAL CHROMATOGRAPHY (2010)

Article Endocrinology & Metabolism

High-cocoa polyphenol-rich chocolate improves HDL cholesterol in Type 2 diabetes patients

D. D. Mellor et al.

DIABETIC MEDICINE (2010)

Article Chemistry, Applied

Optimisation of a CE method for caffeine analysis in decaffeinated coffee

Adriana Dillenburg Meinhart et al.

FOOD CHEMISTRY (2010)

Article Chemistry, Applied

Green tea: A promising anticancer agent for renal cell carcinoma

Marcia Carvalho et al.

FOOD CHEMISTRY (2010)

Article Gastroenterology & Hepatology

Increased Caffeine Consumption Is Associated with Reduced Hepatic Fibrosis

Apurva A. Modi et al.

HEPATOLOGY (2010)

Review Neurosciences

Caffeine, Diabetes, Cognition, and Dementia

Geert Jan Biessels

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Neurosciences

Caffeine and Coffee as Therapeutics Against Alzheimer's Disease

Gary W. Arendash et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Biochemical Research Methods

Quantification of theobromine and caffeine in saliva, plasma and urine via liquid chromatography-tandem mass spectrometry: A single analytical protocol applicable to cocoa intervention studies

Adam S. Ptolemy et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2010)

Article Chemistry, Analytical

Nafion/multi-wall carbon nanotubes composite film coated glassy carbon electrode for sensitive determination of caffeine

Suling Yang et al.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2010)

Article Food Science & Technology

White and Green Teas (Camellia sinensis var. sinensis): Variation in Phenolic, Methylxanthine, and Antioxidant Profiles

Uchenna J. Unachukwu et al.

JOURNAL OF FOOD SCIENCE (2010)

Review Obstetrics & Gynecology

Caffeine impact on neonatal morbidities

Jacob V. Aranda et al.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE (2010)

Review Nutrition & Dietetics

Caffeine-Not just a stimulant

Michael J. Glade

NUTRITION (2010)

Article Nutrition & Dietetics

The Effects of Ginseng, Ephedrine, and Caffeine on Cognitive Performance, Mood and Energy

Harris R. Lieberman

NUTRITION REVIEWS (2010)

Article Physiology

Methylxanthine reversal of opioid-evoked inspiratory depression via phosphodiesterase-4 blockade

Araya Ruangkittisakul et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2010)

Review Obstetrics & Gynecology

Caffeine in pregnancy

Krzysztof M. Kuczkowski

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2009)

Article Developmental Biology

Maternal Caffeine Consumption and Risk of Neural Tube Defects

Rebecca J. Schmidt et al.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2009)

Article Endocrinology & Metabolism

Roles of cAMP signalling in insulin granule exocytosis

S. Seino et al.

DIABETES OBESITY & METABOLISM (2009)

Article Endocrinology & Metabolism

Coffee and tea consumption and risk of type 2 diabetes

S. van Dieren et al.

DIABETOLOGIA (2009)

Article Food Science & Technology

Comparative study of commercially available cocoa products in terms of their bioactive composition

Ana Belscak et al.

FOOD RESEARCH INTERNATIONAL (2009)

Article Biology

1-Methylxanthine enhances the radiosensitivity of tumor cells

Hyewon Youn et al.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2009)

Article Neurosciences

Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice

Chuanhai Cao et al.

JOURNAL OF ALZHEIMERS DISEASE (2009)

Article Neurosciences

Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia: A Population-Based CAIDE Study

Marjo H. Eskelinen et al.

JOURNAL OF ALZHEIMERS DISEASE (2009)

Article Agriculture, Dairy & Animal Science

Improved Fertility in Gilts and Sows after Artificial Insemination of Frozen-Thawed Boar Semen by Supplementation of Semen Extender with Caffeine and CaCl2

Shoichiro Yamaguchi et al.

JOURNAL OF REPRODUCTION AND DEVELOPMENT (2009)

Article Chemistry, Analytical

Separation of catechins and methylxanthines in tea samples by capillary electrochromatography

Ulku Dilek Uysal et al.

JOURNAL OF SEPARATION SCIENCE (2009)

Article Food Science & Technology

Rapid Determination of Theophylline, Theobromine and Caffeine in Dietary Supplements Containing Guarana by Ultra-Performance Liquid Chromatography

Takashi Hasegawa et al.

JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN (2009)

Article Biochemistry & Molecular Biology

The Effects of Caffeine on l-Arginine Metabolism in the Brain of Rats

Ebru Ofluoglu et al.

NEUROCHEMICAL RESEARCH (2009)

Article Obstetrics & Gynecology

Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study

Xiaoping Weng et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2008)

Review Biochemistry & Molecular Biology

Modulation of cellular response to anticancer treatment by caffeine: Inhibition of cell cycle checkpoints, DNA repair and more

Michal Sabisz et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2008)

Review Biochemistry & Molecular Biology

Adenosine receptor antagonists for cognitive dysfunction: a review of animal studies

Reinaldo Naoto Takahashi et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2008)

Article Agriculture, Multidisciplinary

Predictive relationship between polyphenol and nonfat cocoa solids content of chocolate

Karen A. Cooper et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)

Article Biochemical Research Methods

Simultaneous HPLC determination of caffeine, theobromine, and theophylline in food, drinks, and herbal products

Branislava Srdjenovic et al.

JOURNAL OF CHROMATOGRAPHIC SCIENCE (2008)

Article Biochemistry & Molecular Biology

Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum

Xuesong Chen et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Immunology

Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

Xuesong Chen et al.

JOURNAL OF NEUROINFLAMMATION (2008)

Article Pharmacology & Pharmacy

Safety issues associated with commercially available energy drinks

Kevin A. Clauson et al.

JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION (2008)

Review Endocrinology & Metabolism

A short history of beverages and how our body treats them

A. Wolf et al.

OBESITY REVIEWS (2008)

Review Biochemistry & Molecular Biology

Caffeine and related purine alkaloids: Biosynthesis, catabolism, function and genetic engineering

Hiroshi Ashihara et al.

PHYTOCHEMISTRY (2008)

Article Spectroscopy

Simultaneous spectrophotometric determination of paracetamol, ibuprofen and caffeine in pharmaceuticals by chemometric methods

M. R. Khoshayand et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2008)

Article Immunology

Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

Xuesong Chen et al.

JOURNAL OF NEUROINFLAMMATION (2008)

Article Medicine, General & Internal

Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study

Sinead Boylan et al.

BMJ-BRITISH MEDICAL JOURNAL (2008)

Article Nutrition & Dietetics

Prospective study of coffee consumption and risk of Parkinson's disease

K. Saaksjarvi et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2008)

Review Biochemistry & Molecular Biology

Caffeine analogs: biomedical impact

J. W. Daly

CELLULAR AND MOLECULAR LIFE SCIENCES (2007)

Article Developmental Biology

Maternal caffeine consumption and risk of cardiovascular malformations

Marilyn L. Browne et al.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2007)

Review Oncology

The enigmatic effects of caffeine in cell cycle and cancer

Ann M. Bode et al.

CANCER LETTERS (2007)

Article Medicine, General & Internal

Effect of reducing caffeine intake on birth weight and length of gestation: randomised controlled trial

Bodil Hammer Bech et al.

BMJ-BRITISH MEDICAL JOURNAL (2007)

Article Nutrition & Dietetics

Coffee consumption is inversely associated with cognitive decline in elderly European men: the FINE Study

B. M. van Gelder et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2007)

Article Pharmacology & Pharmacy

Role of adenosine receptors in the regulation of angiogenic factors and neovascularization in hypoxia

Sergey Ryzhov et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Review Pharmacology & Pharmacy

Novel 8-heterocyclyl xanthine derivatives in drug development - an update

Pier G. Baraldi et al.

EXPERT OPINION ON DRUG DISCOVERY (2007)

Article Public, Environmental & Occupational Health

Coffee and sweetened beverage consumption and the risk of type 2 diabetes mellitus - The atherosclerosis risk in communities study

Nina P. Paynter et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2006)

Article Chemistry, Analytical

Caffeine content of decaffeinated coffee

Rachel R. McCusker et al.

JOURNAL OF ANALYTICAL TOXICOLOGY (2006)

Article Medicine, General & Internal

Coffee consumption and risk of type 2 diabetes mellitus - An 11-year prospective study of 28 812 postmenopausal women

MA Pereira et al.

ARCHIVES OF INTERNAL MEDICINE (2006)

Article Biochemistry & Molecular Biology

Regulation of the body fat percentage in developmental-stage rats by methylxanthine derivatives in a high-fat diet

Hiroko Inoue et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2006)

Article Agriculture, Multidisciplinary

Catechin and caffeine content of green tea dietary supplements and correlation with antioxidant capacity

NP Seeram et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)

Review Chemistry, Medicinal

Progress in the pursuit of therapeutic adenosine receptor antagonists

S Moro et al.

MEDICINAL RESEARCH REVIEWS (2006)

Article Nutrition & Dietetics

Changes in caffeine intake and long-term weight change in men and women

E Lopez-Garcia et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)

Review Pharmacology & Pharmacy

Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma

C Russo et al.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2006)

Article Biochemistry & Molecular Biology

Methylxanthine drugs are chitinase inhibitors: Investigation of inhibition and binding modes

FV Rao et al.

CHEMISTRY & BIOLOGY (2005)

Article Chemistry, Applied

A new procedure for caffeine determination

VV Khasanov et al.

RUSSIAN JOURNAL OF APPLIED CHEMISTRY (2005)

Article Chemistry, Analytical

Solid-phase FT-Raman determination of caffeine in energy drinks

S Armenta et al.

ANALYTICA CHIMICA ACTA (2005)

Review Medicine, General & Internal

Coffee consumption and risk of type 2 diabetes - A systematic review

RM van Dam et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

Article Endocrinology & Metabolism

Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation

MS Westerterp-Plantenga et al.

OBESITY RESEARCH (2005)

Article Biochemical Research Methods

Solid-phase ultraviolet sensing system for determination of methylxanthines

EJ Llorent-Martínez et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2005)

Article Pharmacology & Pharmacy

Requirement of intact adenosine a1 receptors for the diuretic and natriuretic action of the methylxanthines theophylline and caffeine

T Rieg et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)

Review Pharmacology & Pharmacy

Uric acid and oxidative stress

GK Glantzounis et al.

CURRENT PHARMACEUTICAL DESIGN (2005)

Article Nutrition & Dietetics

Food sources and intakes of caffeine in the diets of persons in the United States

CD Frary et al.

JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION (2005)

Article Biochemistry & Molecular Biology

Caffeine synthase and related methyltransferases in plants

M Kato et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2004)

Article Biochemistry & Molecular Biology

Distribution and biosynthesis of caffeine in plants

H Ashihara et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2004)

Article Oncology

Caffeine inhibits cell proliferation by G0/G1 phase arrest in JB6 cells

T Hashimoto et al.

CANCER RESEARCH (2004)

Article Pharmacology & Pharmacy

Phosphodiesterase inhibitors as anti-cancer drugs

L Hirsh et al.

BIOCHEMICAL PHARMACOLOGY (2004)

Article Immunology

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages

BG Cosio et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Article Biochemistry & Molecular Biology

Theobromine inhibits sensory nerve activation and cough

OS Usmani et al.

FASEB JOURNAL (2004)

Article Biochemistry & Molecular Biology

Purine alkaloids in Paullinia

CS Weckerle et al.

PHYTOCHEMISTRY (2003)

Article Neurosciences

Association between A2a receptor gene polymorphisms and caffeine-induced anxiety

K Alsene et al.

NEUROPSYCHOPHARMACOLOGY (2003)

Article Cell Biology

Caffeine analogs:: Effects on ryanodine-sensitive calcium-release channels and GABAA receptors

D Shi et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2003)

Article Biochemistry & Molecular Biology

RNA binding efficacy of theophylline, theobromine and caffeine

IM Johnson et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2003)

Article Agriculture, Multidisciplinary

Factors affecting the levels of tea polyphenols and caffeine in tea leaves

YS Lin et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)

Article Agriculture, Multidisciplinary

Fast determination of catechins and xanthines in tea beverages by micellar electrokinetic chromatography

M Bonoli et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)

Review Chemistry, Applied

Effects of caffeine on human health

P Nawrot et al.

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT (2003)

Review Plant Sciences

Purine and pyrimidine nucleotide metabolism in higher plants

C Stasolla et al.

JOURNAL OF PLANT PHYSIOLOGY (2003)

Article Medicine, General & Internal

Coffee consumption and risk of type 2 diabetes mellitus

RM van Dam et al.

LANCET (2002)

Article Public, Environmental & Occupational Health

Coffee consumption and cognitive function among older adults

M Johnson-Kozlow et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2002)

Article Food Science & Technology

Optimized method for simultaneous determination of catechin, gallic acid, and methylxanthine compounds in chocolate using RP-HPLC

Ö Tokusoglu et al.

EUROPEAN FOOD RESEARCH AND TECHNOLOGY (2002)

Article Biology

Effects of caffeine on learning and memory in rats tested in the Morris water maze

MEM Angelucci et al.

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2002)

Article Multidisciplinary Sciences

Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice

YP Lu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Chemistry, Medicinal

8-aryl xanthines potent inhibitors of phosphodiesterase 5

R Arnold et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)

Article Public, Environmental & Occupational Health

Risk factors for Alzheimer's disease:: A prospective analysis from the Canadian Study of Health and Aging

J Lindsay et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2002)

Article Agriculture, Multidisciplinary

Extraction of methylxanthines from guarana seeds, mate leaves, and cocoa beans using supercritical carbon dioxide and ethanol

MDA Saldaña et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2002)

Article Chemistry, Applied

Rapid determination of caffeine content in soft drinks using FTIR-ATR spectroscopy

MM Paradkar et al.

FOOD CHEMISTRY (2002)

Article Clinical Neurology

Does caffeine intake protect from Alzheimer's disease?

L Maia et al.

EUROPEAN JOURNAL OF NEUROLOGY (2002)

Article Multidisciplinary Sciences

Pest control: Caffeine as a repellent for slugs and snails

RG Hollingsworth et al.

NATURE (2002)

Article Multidisciplinary Sciences

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression

K Ito et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemical Research Methods

Simultaneous determination of caffeine, theobromine, and theophylline by high-performance liquid chromatography

MS Bispo et al.

JOURNAL OF CHROMATOGRAPHIC SCIENCE (2002)

Article Ophthalmology

Effects of caffeine on microcirculation of the human ocular fundus

T Okuno et al.

JAPANESE JOURNAL OF OPHTHALMOLOGY (2002)

Review Biochemistry & Molecular Biology

Effect of methylxanthine derivatives on doxorubicin transport and antitumor activity

A Kakuyama et al.

CURRENT DRUG METABOLISM (2001)

Article Agriculture, Multidisciplinary

Factors affecting the caffeine and polyphenol contents of black and green tea infusions.

C Astill et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2001)

Article Clinical Neurology

Prospective study of caffeine consumption and risk of Parkinson's disease in men and women

A Ascherio et al.

ANNALS OF NEUROLOGY (2001)

Article Neurosciences

Inhibitory effect of theophylline on recombinant GABAA receptor

T Sugimoto et al.

NEUROREPORT (2001)

Article Food Science & Technology

Improved analysis of theobromine and caffeine in chocolate food products formulated with cocoa powder

AG Caudle et al.

FOOD RESEARCH INTERNATIONAL (2001)

Article Physiology

Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance

F Greer et al.

JOURNAL OF APPLIED PHYSIOLOGY (2000)

Article Biochemical Research Methods

Liquid chromatographic method for the simultaneous determination of caffeine and fourteen caffeine metabolites in urine

EK Bendriss et al.

JOURNAL OF CHROMATOGRAPHY B (2000)

Review Neurosciences

Alkylxanthines as research tools

JW Daly

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM (2000)

Article Pediatrics

Current options in the management of apnea of prematurity

J Bhatia

CLINICAL PEDIATRICS (2000)

Article Medicine, General & Internal

Association of coffee and caffeine intake with the risk of Parkinson disease

GW Ross et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

Article Biochemistry & Molecular Biology

Caffeine abolishes the mammalian G2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

BBS Zhou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Biochemical Research Methods

Improved micro-method for the HPLC analysis of caffeine and its demethylated metabolites in human biological fluids after SPE

KA Georga et al.

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES (2000)