Journal
MOLECULES
Volume 21, Issue 1, Pages -Publisher
MDPI AG
DOI: 10.3390/molecules21010072
Keywords
structure-activity relationship; antioxidant peptides; proteins
Funding
- National Natural Science Foundation of China [81302416]
- Guangdong Science and Technology Planning Project [2013B031800016]
- Doctoral Scientific Research Foundation of Guangdong Medical University [XB13010]
- Dongguan Key Laboratory of Environmental Medicine
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Peptides derived from dietary proteins, have been reported to display significant antioxidant activity, which may exert notably beneficial effects in promoting human health and in food processing. Recently, much research has focused on the generation, separation, purification and identification of novel peptides from various protein sources. Some researchers have tried to discover the structural characteristics of antioxidant peptides in order to lessen or avoid the tedious and aimless work involving the ongoing generated peptide preparation schemes. This review aims to summarize the current knowledge on the relationship between the structural features of peptides and their antioxidant activities. The relationship between the structure of the precursor proteins and their abilities to release antioxidant fragments will also be summarized and inferred. The preparation methods and antioxidant capacity evaluation assays of peptides and a prediction scheme of quantitative structure-activity relationship (QSAR) will also be pointed out and discussed.
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