Related references
Note: Only part of the references are listed.Macrocyclic Drugs and Clinical Candidates: What Can Medicinal Chemists Learn from Their Properties?
Fabrizio Giordanetto et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Synthesis of spiropyrrolidinyl-benzoisothiazoline derivatives by 1,3-dipolar cycloaddition of benzbisothiazole-2,2-dioxide-3-ylidenes and azomethine ylide
Guorui Cao et al.
TETRAHEDRON (2014)
Macrocycles in new drug discovery
Jamie Mallinson et al.
FUTURE MEDICINAL CHEMISTRY (2012)
Echinocandins: Addressing outstanding questions surrounding treatment of invasive fungal infections
Shannon L. Holt et al.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2011)
A spirocyclic oxindole analogue: Synthesis and antitumor activities
Hui Hong et al.
CHINESE CHEMICAL LETTERS (2011)
An improved and scalable process for 3,8-diazabicyclo[3.2.1] octane analogues
Long Jiang Huang et al.
CHINESE CHEMICAL LETTERS (2011)
Echinocandin Antifungal Drugs in Fungal Infections A Comparison
Sharon C. -A. Chen et al.
DRUGS (2011)
Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery
Eric Marsault et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Synthesis of Vaniprevir (MK-7009): Lactamization To Prepare a 22-Membered Macrocycle
Zhiguo J. Song et al.
JOURNAL OF ORGANIC CHEMISTRY (2011)
Comparison of diffusion coefficients for matched pairs of macrocyclic and linear molecules over a drug-like molecular weight range
Andrew R. Bogdan et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2011)
Discovery of Vaniprevir (MK-7009), a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor
John A. McCauley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Accessing Skeletal Diversity Using Catalyst Control: Formation of n and n+1 Macrocyclic Triazole Rings
Ann Rowley Kelly et al.
ORGANIC LETTERS (2009)
A facile and regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles using click chemistry
Dalip Kumar et al.
TETRAHEDRON LETTERS (2009)
Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)
Scott D. Seiwert et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Total synthesis of the cyclopeptide alkaloid paliurine E. insights into macrocyclization by ene-enamide RCM
Mathieu Toumi et al.
JOURNAL OF ORGANIC CHEMISTRY (2008)
Ruthenium-catalyzed azide-alkyne cycloaddition: Scope and mechanism
Brant C. Boren et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
The exploration of macrocycles for drug discovery - an underexploited structural class
Edward M. Driggers et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Ruthenium-catalyzed cycloaddition of aryl azides and alkynes
Lars Kyhn Rasmussen et al.
ORGANIC LETTERS (2007)
Oligomers as intermediates in ring-closing metathesis
Jay C. Conrad et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Copper-catalyzed synthesis of N-sulfonyl-1,2,3-triazoles: Controlling selectivity
Eun Jeong Yoo et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Macrocyclization by ring-closing metathesis in the total synthesis of natural products: Reaction conditions and limitations
Ana Gradillas et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
Ruthenium-catalyzed cycloaddition of alkynes and organic azides
L Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
What can a chemist learn from nature's macrocycles? - A brief, conceptual view
Ludger A. Wessjohann et al.
MOLECULAR DIVERSITY (2005)
Alkyne metathesis
A Furstner et al.
CHEMICAL COMMUNICATIONS (2005)
Ring synthesis by stereoselective, methylene-free enyne cross metathesis
AA Kulkarni et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Efficiency and fidelity in a click-chemistry route to triazole dendrimers by the copper(I)-catalyzed ligation of azides and alkynes
P Wu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients
H Hinrichsen et al.
GASTROENTEROLOGY (2004)
The echinocandin antifungals: an overview of the pharmacology, spectrum and clinical efficacy
NP Wiederhold et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2003)
Bioconjugation by copper(I)-catalyzed azide-alkyne [3+2] cycloaddition
Q Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Biomimetic synthesis and optimization of cyclic peptide antibiotics
RM Kohli et al.
NATURE (2002)
Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides
CW Tornoe et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
Cyclopeptide alkaloids from Paliurus ramossisimus
HY Lin et al.
JOURNAL OF NATURAL PRODUCTS (2000)
An efficient total synthesis of K-13, a non-competitive inhibitor of ACE I
A Bigot et al.
TETRAHEDRON LETTERS (2000)