A New Approach to the Ring-Opening of Epoxides under Mild and Green Conditions

In this research work, we have designed and introduced [Zr-UiO-66-CO2H]Br as a versatile heterogeneous acid catalyst for the ring-opening of epoxides through S(N)1 and/or S(N)2 type mechanisms. In addition, the appropriate method for designing an active and efficient Bronsted acid site in metal-organic frameworks is discussed. [Zr-UiO-66-CO2H]Br was applied for the preparation of a-aryloxy alcohols by the condensation reaction of various epoxides with phenol or thiophenols under mild and green conditions.{GRAPHIACAL ABSTRACT}

Automated summary

In this research, [Zr-UiO-66-CO2H]Br was introduced as a versatile heterogeneous acid catalyst for the ring-opening of epoxides. The study also discusses the appropriate method for designing an active and efficient Bronsted acid site in metal-organic frameworks. [Zr-UiO-66-CO2H]Br was successfully used for the preparation of a-aryloxy alcohols under mild and green conditions.