Cold Atmospheric Plasma as a Therapeutic Tool in Medicine and Dentistry

This comprehensive review explores decade-long research conducted on the applications of Cold Atmospheric Plasma (CAP) and Plasma Activated Liquids (PAL), including Plasma Activated Water (PAW), in the fields of Medicine and Dentistry. CAPs, operating at atmospheric pressure, offer unique advantages over conventional medical devices, generating Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) that interact with substances, enabling diverse applications. The review examined CAP and PAL efficacy against infectious diseases using in vitro, ex vivo, in vivo, and direct application methods. Significant strides were observed in wound healing, cancer treatment, and dental care. However, ensuring patient safety through rigorous plasma source standards remains crucial. The study underscores CAPs and PALs' potential to transform medical and dental therapies, urging further research and development in these groundbreaking technologies. These findings highlight the transformative impact of CAPs and PALs, offering promising avenues for innovative medical and dental treatments.

Automated summary

This comprehensive review summarizes the decade-long research on the applications of Cold Atmospheric Plasma (CAP) and Plasma Activated Liquids (PAL), including Plasma Activated Water (PAW), in Medicine and Dentistry. CAPs, operating at atmospheric pressure, generate Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) that interact with substances, offering unique advantages over conventional medical devices. The study highlights the potential of CAPs and PALs to transform medical and dental therapies, emphasizing the need for further research and development in these groundbreaking technologies. These findings suggest promising avenues for innovative medical and dental treatments, with significant strides observed in wound healing, cancer treatment, and dental care.