Journal
MOLECULES
Volume 21, Issue 5, Pages -Publisher
MDPI AG
DOI: 10.3390/molecules21050607
Keywords
Illicium difengpi; stem barks; lignan glucosides; difengpiosides A-D; NO inhibition
Funding
- Guangxi Scientific Research and Technology Development Program [14125008-2-23]
- Science Research Foundation of Guangxi Institute of Botany [13015]
- Foundation of Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization [ZRJJ2014-2]
- Bagui Scholar Program of Guangxi
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In this study, four new lignan glucosides, named difengpiosides A-D (1-4), were isolated from the stem barks of Illicium difengpi, together with seven known compounds 5-11. Their structures were identified on the basis of spectroscopic analyses (1D and 2D NMR, HRESIMS, CD) and a comparison with literature data. All the compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells.
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