Acute performance, physiological, and perceptual changes in response to repeated cycling sprint exercise combined with systemic and local hypoxia in young males

This study investigated the acute performance, physiological, and perceptual changes during repeated sprint exercise (RSE) under normobaric hypoxia and with blood flow restriction (BFR). Fourteen active males completed standardized RSE (6 x 10 s cycling sprints with 30 s passive rest) in three randomized conditions: under normobaric hypoxia (FiO(2) similar to 14.4%, HYP), normoxia (FiO(2) similar to 20.9%, SHAM), and with BFR (40% arterial occlusion pressure). The percentage decrement score of power output (Sdec) was used to quantify motor per-formance fatigue. During RSE, muscle oxygenation (total and oxygenated hemoglobin) and activity of the right quadriceps were measured. Perceived motor fatigue, physical strain, affective valence, and arousal were queried after each sprint. Blood lactate concentration (BLC) and peripheral oxygenation (SpO2) were measured before and after RSE. Sdec was greater in HYP and BFR compared to SHAM (p <= 0.008). BFR decreased mean power output (p < 0.001) and muscle activity (p = 0.027) compared to SHAM. Decrease in muscle oxygenated he-moglobin was higher in BFR during each rest (p <= 0.005) and in HYP during rest 4 (p = 0.006) compared to SHAM. HYP increased BLC and decreased SpO2 compared to BFR (p < 0.001) and SHAM (p = 0.002). There were no differences between conditions for any rating scale (p >= 0.060). HYP and BFR increased motor performance fatigue but with different physiological responses, whereas perceptual responses were unaffected during RSE.

Automated summary

This study examined the immediate effects of repeated sprint exercise (RSE) under normobaric hypoxia and with blood flow restriction (BFR) on performance, physiology, and perception. The results showed that both hypoxia and BFR led to greater motor performance fatigue with different physiological responses, while there were no significant perceptual changes during RSE. This suggests that training under specific conditions may elicit different physiological adaptations in the body.