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Yi Zhao et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
The role of stem cells and progenitors in the genesis of medulloblastoma
Jun Wang et al.
EXPERIMENTAL NEUROLOGY (2014)
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition
Yujie Tang et al.
NATURE MEDICINE (2014)
Phase 1 Trial of Temsirolimus in Combination with Irinotecan and Temozolomide in Children, Adolescents and Young Adults with Relapsed or Refractory Solid Tumors: A Children's Oncology Group Study
Rochelle Bagatell et al.
PEDIATRIC BLOOD & CANCER (2014)
Initial testing (stage 1) of the investigational mTOR kinase inhibitor MLN0128 by the pediatric preclinical testing program
Min H. Kang et al.
PEDIATRIC BLOOD & CANCER (2014)
Silencing of the miR-17∼92 Cluster Family Inhibits Medulloblastoma Progression
Brian L. Murphy et al.
CANCER RESEARCH (2013)
Discovery of NVP-LEQ506, a Second-Generation Inhibitor of Smoothened
Stefan Peukert et al.
CHEMMEDCHEM (2013)
Phase I Study of Vismodegib in Children with Recurrent or Refractory Medulloblastoma: A Pediatric Brain Tumor Consortium Study
Amar Gajjar et al.
CLINICAL CANCER RESEARCH (2013)
Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma
M. Gutova et al.
GENE THERAPY (2013)
MicroRNA 218 Acts as a Tumor Suppressor by Targeting Multiple Cancer Phenotype-associated Genes in Medulloblastoma
Sujatha Venkataraman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Quantitative analysis of the brain-targeted delivery of drugs and model compounds using nano-delivery systems
Luba Kozlovskaya et al.
JOURNAL OF CONTROLLED RELEASE (2013)
B7-H3, a potential therapeutic target, is expressed in diffuse intrinsic pontine glioma
Zhiping Zhou et al.
JOURNAL OF NEURO-ONCOLOGY (2013)
Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem
Daniel Grammel et al.
ACTA NEUROPATHOLOGICA (2012)
Pleiotropic effects of miR-183∼96∼182 converge to regulate cell survival, proliferation and migration in medulloblastoma
Shyamal Dilhan Weeraratne et al.
ACTA NEUROPATHOLOGICA (2012)
A Mouse Model of the Most Aggressive Subgroup of Human Medulloblastoma
Daisuke Kawauchi et al.
CANCER CELL (2012)
Three decades of Wnts: a personal perspective on how a scientific field developed
Roel Nusse et al.
EMBO JOURNAL (2012)
Norcantharidin impairs medulloblastoma growth by inhibition of Wnt/β-catenin signaling
Flora Cimmino et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
Novel mutations target distinct subgroups of medulloblastoma
Giles Robinson et al.
NATURE (2012)
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
Paul A. Northcott et al.
NATURE (2012)
Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
Aleksandar Sekulic et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Initial testing (stage 1) of the mTOR kinase inhibitor AZD8055 by the pediatric preclinical testing program
Peter J. Houghton et al.
PEDIATRIC BLOOD & CANCER (2012)
Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target
Ninib Baryawno et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Medulloblastoma in childhood: revisiting intrathecal therapy in infants and children
Sharon Conroy et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2010)
HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth
Till Milde et al.
CLINICAL CANCER RESEARCH (2010)
Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects
Kamala Kesavan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development
Xi Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist
Shifeng Pan et al.
ACS MEDICINAL CHEMISTRY LETTERS (2010)
GDC-0449-A potent inhibitor of the hedgehog pathway
Kirk D. Robarge et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma
Tracy-Ann Read et al.
CANCER CELL (2009)
Multipotent CD15(+) Cancer Stem Cells in Patched-1-Deficient Mouse Medulloblastoma
Ryan J. Ward et al.
CANCER RESEARCH (2009)
The miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog-Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehog-Treated Cerebellar Neural Precursors
Paul A. Northcott et al.
CANCER RESEARCH (2009)
MicroRNA profiling in human medulloblastoma
Elisabetta Ferretti et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
AGT-181: Expression in CHO cells and pharmacokinetics, safety, and plasma iduronidase enzyme activity in Rhesus monkeys
Ruben J. Boado et al.
JOURNAL OF BIOTECHNOLOGY (2009)
Synthesis, in vitro and in vivo characterization of glycosyl derivatives of ibuprofen as novel prodrugs for brain drug delivery
Qian Chen et al.
JOURNAL OF DRUG TARGETING (2009)
Glucose Promoiety Enables Glucose Transporter Mediated Brain Uptake of Ketoprofen and Indomethacin Prodrugs in Rats
Mikko Gynther et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma
Tamar Uziel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Medulloblastoma can be initiated by deletion of patched in lineage-restricted progenitors or stem cells
Zeng-Jie Yang et al.
CANCER CELL (2008)
Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program
John M. Maris et al.
PEDIATRIC BLOOD & CANCER (2008)
Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling
W. J. Ingram et al.
ONCOGENE (2008)
Both CD133+ and CD133- medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity
Roberta Castriconi et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin
Xue Qing Lun et al.
CANCER RESEARCH (2007)
Evaluation of poly (glycerol-adipate) nanoparticle uptake in an In Vitro 3-D brain tumor co-culture model
W. Meng et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2007)
Tumor paint:: A Chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci
Mandana Veiseh et al.
CANCER RESEARCH (2007)
Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial
Amar Gajjar et al.
LANCET ONCOLOGY (2006)
Development of the deep cerebellar nuclei: Transcription factors and cell migration from the rhombic lip
AJ Fink et al.
JOURNAL OF NEUROSCIENCE (2006)
Treatment of early childhood medulloblastoma by postoperative chemotherapy alone
S Rutkowski et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Multimutated herpes simplex virus G207 is a potent inhibitor of angiogenesis
J Cinatl et al.
NEOPLASIA (2004)
Tumor mRNA-loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with malignant glioma
T Kobayashi et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2003)
Angiogenic profile of childhood primitive neuroectodermal brain tumours/medulloblastomas
H Huber et al.
EUROPEAN JOURNAL OF CANCER (2001)