☆ 4.5 Review

The role of microRNA-185 in the pathogenesis of human diseases: A focus on cancer

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The Role and Clinical Potentials of Circular RNAs in Prostate Cancer

Mohammad Taheri et al.

Summary: Research on circular RNAs in prostate cancer suggests that they may play a role in promoting the development of the cancer, with some up-regulated circRNAs potentially acting as oncogenes, while down-regulated circRNAs may act as tumor suppressor genes.

FRONTIERS IN ONCOLOGY (2021)

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Review Cell Biology

Biological functions and clinical significance of long noncoding RNAs in bladder cancer

Yan Zhang et al.

Summary: Long noncoding RNAs play a significant role in the development of bladder cancer, and are closely associated with patients' clinicopathological characteristics, with the potential to serve as diagnostic and prognostic biomarkers for bladder cancer patients in the future.

CELL DEATH DISCOVERY (2021)

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Article Cell Biology

Impaired AGO2/miR-185-3p/NRP1 axis promotes colorectal cancer metastasis

Xisheng Liu et al.

Summary: The global downregulation of miRNA expression, potentially due to defects in miRNA processing machinery, is a hallmark of human cancer. In colorectal cancer (CRC), downregulation of the key regulator of miRNA processing, Argonaute 2 (AGO2), has been found to promote epithelial-mesenchymal transition (EMT) and indicate poor prognosis. Knockdown of AGO2 in CRC cells enhanced migration, invasion, and metastasis, while integrated analyses revealed neuropilin 1 (NRP1) as a new substrate of AGO2 via miR-185-3p. Therapeutically targeting the AGO2/miR-185-3p/NRP1 axis may offer a potential treatment approach for CRC.

CELL DEATH & DISEASE (2021)

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Article Cell Biology

MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells

Hongqing Wen et al.

Aging-US (2021)

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Article Medicine, General & Internal

Long Non-Coding RNA FOXD2-AS1 Serves as a Potential Prognostic Biomarker for Patients With Cancer: A Meta-Analysis and Database Testing

Fujiao Duan et al.

Summary: Based on the analysis of 11 studies with a total of 2,177 patients, it was found that high expression of FOXD2-AS1 is significantly correlated with poor overall survival (OS) and disease-free survival (DFS) of cancer patients, especially in the Chinese population. The findings suggest that FOXD2-AS1 may serve as a potential independent prognostic factor in cancer.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2021)

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Article Medicine, Research & Experimental

New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities

Milad Ashrafizadeh et al.

Summary: EMT mechanism is responsible for cancer cell metastasis and migration, as well as drug resistance. Taxene chemotherapeutic agents PTX and DTX induce cancer cell cycle arrest by preventing microtubule depolymerization, while upstream mediators of EMT such as ZEB1/2 and TGF-ll affect cancer cells' response to these drugs.

BIOMEDICINE & PHARMACOTHERAPY (2021)

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Article Biochemical Research Methods

Exosomal ncRNAs profiling of mycobacterial infection identified miRNA-185-5p as a novel biomarker for tuberculosis

Aman Chandra Kaushik et al.

Summary: The study indicates that exosomal ncRNAs may serve as useful functional biomarkers in tuberculosis, with miR-185-5p identified as a potential biomarker for tuberculosis.

BRIEFINGS IN BIOINFORMATICS (2021)

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Article Biotechnology & Applied Microbiology

miR-185-3p targets Annexin-A8 to inhibit proliferation in cervical cancer cells

Wenfang Zhang et al.

Summary: Multiple studies have shown that miRNAs play a role in regulating tumor-related biological functions. This study focused on exploring the role of miR185-3p in cervical cancer, finding that its overexpression suppressed cancer cell proliferation while its downregulation enhanced cell growth. Additionally, the study demonstrated that ANX-A8 is a direct target of miR185-3p in cervical cancer cells.

CYTOTECHNOLOGY (2021)

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Review Biochemistry & Molecular Biology

Interplay between SOX9 transcription factor and microRNAs in cancer

Milad Ashrafizadeh et al.

Summary: SOX9, a critical transcription factor in the SOXE family, regulates the expression of different transcription factors in cancer cells by binding to miRNAs, affecting cancer progression and malignancy. Other non-coding RNAs can also regulate the expression of miRNA/SOX9 to promote/inhibit cancer progression.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Review Oncology

A multidisciplinary approach remains the best strategy to improve and strengthen the management of ovarian cancer (Review)

Luca Falzone et al.

Summary: This article presents recent advancements in the diagnosis, staging, and treatment of ovarian cancer, emphasizing the benefits of a patient-centered care approach and the importance of a multidisciplinary team for the management of ovarian cancer.

INTERNATIONAL JOURNAL OF ONCOLOGY (2021)

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Article Oncology

Serum MicroRNAs as Xerostomia Biomarkers in Patients With Oropharyngeal Cancer Undergoing Radiation Therapy

Bartlomiej Tomasik et al.

Summary: This study aimed to create an efficient prognostic miRNA-based test for severe xerostomia in oropharyngeal cancer patients after primary treatment. The results showed that miR-425-5p and miR-185-5p levels in serum before radiation therapy or during therapy (after 20 Gy) had significant predictive value for severe xerostomia occurrence 3 months after treatment completion. The variability explained by miRNAs appears to be independent from dosimetric data.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2021)

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Review Oncology

Advancing therapy for osteosarcoma

Jonathan Gill et al.

Summary: Osteosarcoma, the most common primary bone cancer in children and young adults, presents challenges in treatment due to its rarity and molecular heterogeneity. Collaborative efforts in biological discoveries, technologies, and therapeutic approaches are expected to advance osteosarcoma treatment and improve patient outcomes. The increasing feasibility of molecular profiling, along with the creation of robust model systems and large tissue banks, has enhanced understanding of osteosarcoma biology.

NATURE REVIEWS CLINICAL ONCOLOGY (2021)

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Review Pharmacology & Pharmacy

Antimicrobial peptides as potential therapeutics for breast cancer

Shahin Aghamiri et al.

Summary: Breast cancer is the most common and deadliest cancer in women worldwide, with notable advances in treatment but still low survival rates for metastatic patients. Antimicrobial peptides (AMPs) have garnered attention for their cost-effectiveness and high specificity, though clinical data on their efficacy is lacking, emphasizing the need for clinical trials.

PHARMACOLOGICAL RESEARCH (2021)

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Review Health Care Sciences & Services

Breast Cancer Treatments: Updates and New Challenges

Anna Burguin et al.

Summary: Breast cancer, the most frequent cancer diagnosed in women worldwide, can be classified into four molecular subtypes for personalized treatment targeting receptors, but resistance and adverse effects remain challenges. Treatments for TNBC and other subgroups are still not standardized, with emerging approaches like immunotherapy and targeting other metabolic pathways gaining attention.

JOURNAL OF PERSONALIZED MEDICINE (2021)

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Review Biochemistry & Molecular Biology

Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

Chen Li et al.

Summary: Exosomes act as mediators of cell-to-cell communication, playing a crucial role in regulating human health and diseases through non-coding RNA. Changes in exosomal ncRNAs may lead to tissue dysfunction, aging, and diseases.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

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Article Biology

Effects of miR-185-5p on replication of hepatitis C virus

Wei Huang et al.

Summary: The study explored the effects of miR-185-5p on the replication of Hepatitis C Virus (HCV) and its interaction with GALNT8. Upregulation of miR-185-5p inhibited HCV replication, while downregulation promoted it. The targeted relationship between miR-185-5p and GALNT8 was verified, suggesting miR-185-5p as a potential target for treating HCV.

OPEN LIFE SCIENCES (2021)

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Article Medicine, Research & Experimental

MicroRNA-185-5p inhibits hepatic gluconeogenesis and reduces fasting blood glucose levels by suppressing G6Pase

Hui Zheng et al.

Summary: MiR-185-5p plays an inhibitory role in hepatic gluconeogenesis by targeting G6Pase to alleviate hyperglycemia. Moreover, the antidiabetic drug metformin can suppress G6Pase by upregulating miR-185-5p expression, leading to the inhibition of hepatic glucose overproduction.

THERANOSTICS (2021)

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Article Medicine, Research & Experimental

Determining breast cancer biomarker status and associated morphological features using deep learning

Paul Gamble et al.

Summary: In this study, deep learning systems were developed to predict breast cancer biomarker status using H&E images. The models provided accurate predictions for ER, PR, and HER2 at both slide-level and patch-level, while interpretability analyses identified specific histological features associated with these markers. This approach may offer a cost-effective and efficient way to improve quality control in breast cancer marker detection.

COMMUNICATIONS MEDICINE (2021)

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Article Nanoscience & Nanotechnology

被撤回的出版物: SOX2 Regulates lncRNA CCAT1/MicroRNA-185-3p/FOXP3 Axis to Affect the Proliferation and Self-Renewal of Cervical Cancer Stem Cells (Retracted article. See vol. 17, 2022)

Li Zhang et al.

Summary: The role of SOX2, CCAT1, miR-185-3p, and FOXP3 in cervical cancer stem cells was discussed, showing that their expressions are associated with clinicopathological features of CC and affect the proliferation and self-renewal ability of stem cells.

NANOSCALE RESEARCH LETTERS (2021)

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Article Medicine, Research & Experimental

Long noncoding RNA LINC00958 promotes the oral squamous cell carcinoma by sponging miR-185-5p/YWHAZ

Zongsheng Wang et al.

LIFE SCIENCES (2020)

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Article Biochemistry & Molecular Biology

LncRNA PCAT6 promotes tumor progression in osteosarcoma via activation of TGF-β pathway by sponging miR-185-5p

Chengdong Zhu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

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Review Cell Biology

miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis

Carmen Elena Condrat et al.

CELLS (2020)

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Article Oncology

Dexmedetomidine suppresses the progression of esophageal cancer via miR-143-3p/epidermal growth factor receptor pathway substrate 8 axis

Peisen Zhang et al.

ANTI-CANCER DRUGS (2020)

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Article Hematology

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Hanyang Lin et al.

BLOOD (2020)

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Article Medicine, Research & Experimental

lncRNA KLF3-AS1 Suppresses Cell Migration and Invasion in ESCC by Impairing miR-185-5p-Targeted KLF3 Inhibition

Jun-Qi Liu et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

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Article Urology & Nephrology

miR-185 inhibits prostate cancer angiogenesis induced by the nodal/ALK4 pathway

Youkong Li et al.

BMC UROLOGY (2020)

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Article Oncology

Clinical Challenges of Immune Checkpoint Inhibitors

Maria de Miguel et al.

CANCER CELL (2020)

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Article Biology

Circ_001569 regulates FLOT2 expression to promote the proliferation, migration, invasion and EMT of osteosarcoma cells through sponging miR-185-5p

Bin Xiao et al.

OPEN LIFE SCIENCES (2020)

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Article Oncology

Small Non-Coding RNA Profiling in Plasma Extracellular Vesicles of Bladder Cancer Patients by Next-Generation Sequencing: Expression Levels of miR-126-3p and piR-5936 Increase with Higher Histologic Grades

Alexandru A. Sabo et al.

CANCERS (2020)

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Review Oncology

Non-coding RNAs in cancer: platforms and strategies for investigating the genomic dark matter

Katia Grillone et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)

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Article Genetics & Heredity

Comparative analysis of epi-miRNA expression levels in local/locally advanced and metastatic prostate cancer patients

Venhar Gurbuz et al.

GENE (2020)

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Article Biotechnology & Applied Microbiology

Analysis of Key Genes Regulating the Warburg Effect in Patients with Gastrointestinal Cancers and Selective Inhibition of This Metabolic Pathway in Liver Cancer Cells

Xinyue Zhang et al.

ONCOTARGETS AND THERAPY (2020)

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Article Biotechnology & Applied Microbiology

Long Non-Coding RNA Taurine Upregulated Gene I Targets miR-185 to Regulate Cell Proliferation and Glycolysis in Acute Myeloid Leukemia Cells in vitro

Weide Zhang et al.

ONCOTARGETS AND THERAPY (2020)

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Article Biotechnology & Applied Microbiology

LINC00511 Promotes Osteosarcoma Tumorigenesis and Invasiveness through the miR-185-3p/E2F1 Axis

Jun Xu et al.

BIOMED RESEARCH INTERNATIONAL (2020)

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Review Oncology

Receptor for Advanced Glycation End Products Acts as a Fuel to Colorectal Cancer Development

Fatemeh Azizian-Farsani et al.

FRONTIERS IN ONCOLOGY (2020)

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Review Virology

miRNAs as Potential Biomarkers for Viral Hepatitis B and C

Dimitri Loureiro et al.

VIRUSES-BASEL (2020)

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Review Oncology

Emerging Role and Therapeutic Potential of lncRNAs in Colorectal Cancer

Laura Schwarzmueller et al.

CANCERS (2020)

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Article Respiratory System

A comprehensive analysis of microRNAs as diagnostic biomarkers for asthma

Li Xu et al.

THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE (2020)

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Article Oncology

MiR-185-3p regulates epithelial mesenchymal transition via PI3K/Akt signaling pathway by targeting cathepsin D in gastric cancer cells

Cheng Huang et al.

TRANSLATIONAL CANCER RESEARCH (2020)

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Article Oncology

Serum miR-185 Is a Diagnostic and Prognostic Biomarker for Non-Small Cell Lung Cancer

Jinghao Liu et al.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2020)

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Article Oncology

LncRNA MALAT1 accelerates non-small cell lung cancer progression via regulating miR-185-5p/MDM4 axis

Dan Wang et al.

CANCER MEDICINE (2020)

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Article Virology

MicroRNA-185 reduces the expression of hepatitis B virus surface antigen by targeting PRKCH in HepG2 2.2.15 cells

R. Zhang et al.

ACTA VIROLOGICA (2020)

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Article Biology

miR-185-5p response to usnic acid suppresses proliferation and regulating apoptosis in breast cancer cell by targeting Bcl2

Elif Degerli et al.

BIOLOGICAL RESEARCH (2020)

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Article Oncology

Association between Lymph Node Status and Expression Levels of Androgen Receptor, miR-185, miR-205, and miR-21 in Breast Cancer Subtypes

Tatiana S. Kalinina et al.

INTERNATIONAL JOURNAL OF BREAST CANCER (2020)

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Article Mathematical & Computational Biology

Identification of circulating miRNAs as novel prognostic biomarkers for bladder cancer

Guobing Lin et al.

MATHEMATICAL BIOSCIENCES AND ENGINEERING (2020)

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Article Oncology

miR-185 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer by Targeting KLF7

Lili Zhao et al.

ONCOLOGY RESEARCH (2019)

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Article Allergy

Asthma diagnosis using integrated analysis of eosinophil microRNAs

Jose M. Rodrigo-Munoz et al.

ALLERGY (2019)

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Review Oncology

The functional roles of exosomes-derived long non-coding RNA in human cancer

Feiyu Chen et al.

CANCER BIOLOGY & THERAPY (2019)

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Article Cell Biology

miR-185 silencing promotes the progression of atherosclerosis via targeting stromal interaction molecule 1

Ming Fang et al.

CELL CYCLE (2019)

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Article Genetics & Heredity

MicroRNA-185 inhibits proliferation, migration and invasion in human osteosarcoma MG63 cells by targeting vesicle-associated membrane protein 2

Linjun Li et al.

GENE (2019)

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Article Health Care Sciences & Services

Early Detection of Skin Cancer Using Melanoma Segmentationtechnique

Tammineni Sreelatha et al.

JOURNAL OF MEDICAL SYSTEMS (2019)

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Article Medicine, Research & Experimental

SOX9 drives the epithelial-mesenchymal transition in non-small-cell lung cancer through the Wnt/-catenin pathway

Jing-Qiang Huang et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2019)

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Article Biochemistry & Molecular Biology

MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells

Zhong Zheng et al.

MOLECULAR CANCER (2019)

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Article Endocrinology & Metabolism

Circulating microRNAs in plasma among men with low-grade and high-grade prostate cancer at prostate biopsy

Alicia C. McDonald et al.

PROSTATE (2019)

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Article Multidisciplinary Sciences

Circulating microRNAs as Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma

Yu Jin et al.

SCIENTIFIC REPORTS (2019)

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Article Biotechnology & Applied Microbiology

Delivery of mesenchymal stem cells-derived extracellular vesicles with enriched miR-185 inhibits progression of OPMD

Lin Wang et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

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Review Medical Laboratory Technology

Exosomes: A new approach to asthma pathology

Jose A. Canas et al.

CLINICA CHIMICA ACTA (2019)

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Review Geriatrics & Gerontology

Involvement of plasma miRNAs, muscle miRNAs and mitochondrial miRNAs in the pathophysiology of frailty

Iryna Rusanova et al.

EXPERIMENTAL GERONTOLOGY (2019)

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Article Cell Biology

KCNQ1OT1 promotes migration and inhibits apoptosis by modulating miR-185-5p/Rab14 axis in oral squamous cell carcinoma

Qiyan Bao et al.

DEVELOPMENT GROWTH & DIFFERENTIATION (2019)

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Article Medicine, General & Internal

Management of frailty: opportunities, challenges, and future directions

Elsa Dent et al.

LANCET (2019)

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Review Gastroenterology & Hepatology

Circulating microRNAs for the diagnosis of hepatocellular carcinoma

Cheng Peng et al.

DIGESTIVE AND LIVER DISEASE (2019)

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Article Oncology

Serum microRNA expression profiling identifies serum biomarkers for HCV-related hepatocellular carcinoma

Jian Li et al.

CANCER BIOMARKERS (2019)

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Review Medicine, General & Internal

Cervical cancer

Paul A. Cohen et al.

LANCET (2019)

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Article Medicine, Research & Experimental

Long Noncoding RNA (lncRNA) FOXD2-AS1 Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Regulating MiR-185/AKT Axis

Zheng Chen et al.

MEDICAL SCIENCE MONITOR (2019)

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Article Biochemistry & Molecular Biology

XIST promotes gastric cancer (GC) progression through TGF-β1 via targeting miR-185

Quan Zhang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

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Article Medicine, Research & Experimental

MiR-185 enhances radiosensitivity of colorectal cancer cells by targeting IGF1R and IGF2

Saeid Afshar et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

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Article Oncology

Long non-coding RNA FOXD2-AS1 contributes to colorectalcancer proliferation through its interaction withmicroRNA-185-5p

Yanyan Zhu et al.

CANCER SCIENCE (2018)

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Article Pharmacology & Pharmacy

miRNA-185 serves as a prognostic factor and suppresses migration and invasion through Wnt1 in colon cancer

Wenjun Zhang et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2018)

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Review Biochemistry & Molecular Biology

Role of MicroRNAs in Renal Parenchymal DiseasesA New Dimension

Saeed Kamran Shaffi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

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Article Oncology

Integrin-β5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating β-catenin stability

Zhikun Lin et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)

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Review Medicine, General & Internal

Asthma

Alberto Papi et al.

LANCET (2018)

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Article Multidisciplinary Sciences

Optimizing miRNA-module diagnostic biomarkers of gastric carcinoma via integrated network analysis

Fengbin Zhang et al.

PLOS ONE (2018)

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Article Reproductive Biology

S-allylcysteine suppresses ovarian cancer cell proliferation by DNA methylation through DNMT1

Yasi Xu et al.

JOURNAL OF OVARIAN RESEARCH (2018)

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Article Medicine, Research & Experimental

miR-185 Inhibits Fibrogenic Activation of Hepatic Stellate Cells and Prevents Liver Fibrosis

Li Zhou et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

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Review Oncology

Unraveling the Role of Angiogenesis in Cancer Ecosystems

Iratxe Zuazo-Gaztelu et al.

FRONTIERS IN ONCOLOGY (2018)

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Article Medicine, Research & Experimental

Expression of microRNA Potentially Regulated by AhR and CAR in Malignant Tumors of the Endometrium

D. S. Ushakov et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2018)

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Article Genetics & Heredity

被撤回的出版物: Long non-coding RNA UCA1 targets miR-185-5p and regulates cell mobility by affecting epithelial-mesenchymal transition in melanoma via Wnt/beta-catenin signaling pathway (Retracted article. See vol. 795, 2021)

Xige Chen et al.

GENE (2018)

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Article Oncology

A miRNA Combination as Promising Biomarker for Hepatocellular Carcinoma Diagnosis: A Study Based on Bioinformatics Analysis

Jia Ji et al.

JOURNAL OF CANCER (2018)

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Review Allergy

Eosinophils: Old Players in a New Game

B. Sastre et al.

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY (2018)

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Article Medicine, Research & Experimental

MiR-185-5p suppresses HBV gene expression by targeting ELK1 in hepatoma carcinoma cells

Hong-Xia Fan et al.

LIFE SCIENCES (2018)

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Article Medicine, General & Internal

RSF-1 overexpression determines cancer progression and drug resistance in cervical cancer

Xiangyu Wang et al.

BIOMEDICINE-TAIWAN (2018)

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Article Pathology

MicroRNA expression profiling of Xp11 renal cell carcinoma

Luigi Marchionni et al.

HUMAN PATHOLOGY (2017)

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Article Oncology

Tumor Suppressor microRNAs Contribute to the Regulation of PD-L1 Expression in Malignant Pleural Mesothelioma

Steven C. Kao et al.

JOURNAL OF THORACIC ONCOLOGY (2017)

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Review Endocrinology & Metabolism

Regulation of hepatic glucose metabolism in health and disease

Max C. Petersen et al.

NATURE REVIEWS ENDOCRINOLOGY (2017)

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Review Oncology

Epithelial-mesenchymal transition and gastric cancer stem cell

Pu Xia et al.

TUMOR BIOLOGY (2017)

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Article Oncology

MicroRNA-185 induces potent autophagy via AKT signaling in hepatocellular carcinoma

Li Zhou et al.

TUMOR BIOLOGY (2017)

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Article Biotechnology & Applied Microbiology

Expression of urinary miRNAs targeting NLRs inflammasomes in bladder cancer

Ettore Mearini et al.

ONCOTARGETS AND THERAPY (2017)

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Article Oncology

miR-185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He et al.

ONCOLOGY LETTERS (2017)

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Article Oncology

miR-185-3p regulates the invasion and metastasis of nasopharyngeal carcinoma by targeting WNT2B in vitro

Chao Liu et al.

ONCOLOGY LETTERS (2017)

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Article Multidisciplinary Sciences

Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma

Qingbo Huang et al.

NATURE COMMUNICATIONS (2017)

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Article Clinical Neurology

Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases

Kira S. Sheinerman et al.

ALZHEIMERS RESEARCH & THERAPY (2017)

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Article Medicine, Research & Experimental

The lncRNA PDIA3P Interacts with miR-185-5p to Modulate Oral Squamous Cell Carcinoma Progression by Targeting Cyclin D2

Cheng-Cao Sun et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2017)

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Review Immunology

Novel Modulators of Asthma and Allergy: Exosomes and MicroRNAs

Beatriz Sastre et al.

FRONTIERS IN IMMUNOLOGY (2017)

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Review Plant Sciences

New technologies accelerate the exploration of non-coding RNAs in horticultural plants

Degao Liu et al.

HORTICULTURE RESEARCH (2017)

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Review Oncology

Long non-coding RNAs and prostate cancer

Aya Misawa et al.

CANCER SCIENCE (2017)

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Review Pharmacology & Pharmacy

Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine

Maud A. S. Weerink et al.

CLINICAL PHARMACOKINETICS (2017)

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Review Cell Biology

MicroRNA as Biomarkers and Diagnostics

Jin Wang et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2016)

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Article Oncology

MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints

Jun Wei et al.

NEURO-ONCOLOGY (2016)

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Article Dermatology

Identification of a Circulating MicroRNA Profile as a Biomarker of Metastatic Cutaneous Melanoma

Virginie Armand-Labit et al.

ACTA DERMATO-VENEREOLOGICA (2016)

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Article Pathology

TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers

Pedram Argani et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2016)

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Article Biochemistry & Molecular Biology

RKIP suppresses the proliferation and metastasis of breast cancer cell lines through up-regulation of miR-185 targeting HMGA2

Qiongyan Zou et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2016)

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Letter Allergy

Serum periostin is associated with type 2 immunity in severe asthma

Mats W. Johansson et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

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Review Cell Biology

MicroRNA-Regulated Proinflammatory Cytokines in Sarcopenia

Jingjing Fan et al.

MEDIATORS OF INFLAMMATION (2016)

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Article Cell Biology

MiR-185 attenuates androgen receptor function in prostate cancer indirectly by targeting bromodomain containing 8 isoform 2, an androgen receptor co-activator

Chen-Yi Jiang et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2016)

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Review Pediatrics

Acute myeloid leukemia in children: Current status and future directions

Takashi Taga et al.

PEDIATRICS INTERNATIONAL (2016)

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Review Oncology

miRNA Deregulation in Cancer Cells and the Tumor Microenvironment

Rajesha Rupaimoole et al.

CANCER DISCOVERY (2016)

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Review Chemistry, Medicinal

Molecular mechanisms of cisplatin resistance in cervical cancer

Haiyan Zhu et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2016)

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Article

Novel diagnostic and prognostic classifiers for prostate cancer identified by genome-wide microRNA profiling

Helle Kristensen et al.

Oncotarget (2016)

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Article Cardiac & Cardiovascular Systems

microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator

Huajun Jiang et al.

ATHEROSCLEROSIS (2015)

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Article Genetics & Heredity

IL-10Rα expression is post-transcriptionally regulated by miR-15a, miR-185, and miR-211 in melanoma

Isabella Venza et al.

BMC MEDICAL GENOMICS (2015)

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Review Cell Biology

Epigenetic signaling in schizophrenia

Daisuke Ibi et al.

CELLULAR SIGNALLING (2015)

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Review Chemistry, Medicinal

miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart

Bianca C. Bernardo et al.

FUTURE MEDICINAL CHEMISTRY (2015)

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Article Oncology

MicroRNA-185 is a novel tumor suppressor by negatively modulating the Wnt/β-catenin pathway in human colorectal cancer

W. Dong-xu et al.

INDIAN JOURNAL OF CANCER (2015)

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Article Oncology

Plasma miRNAs as early biomarkers for detecting hepatocellular carcinoma

Yang Wen et al.

INTERNATIONAL JOURNAL OF CANCER (2015)

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Review Nanoscience & Nanotechnology

Clinical and pathological implications of miRNA in bladder cancer

Cornelia Braicu et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)

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Article Oncology

MicroRNA-185 downregulates androgen receptor expression in the LNCaP prostate carcinoma cell line

Chunyan Liu et al.

MOLECULAR MEDICINE REPORTS (2015)

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Article Medicine, Research & Experimental

MiR-185-3p and miR-324-3p Predict Radiosensitivity of Nasopharyngeal Carcinoma and Modulate Cancer Cell Growth and Apoptosis by Targeting SMAD7

Jianhua Xu et al.

MEDICAL SCIENCE MONITOR (2015)

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Article Oncology

MicroRNA-185 is a novel tumor suppressor by negatively modulating the Wnt/β-catenin pathway in human colorectal cancer

W. Dong-xu et al.

INDIAN JOURNAL OF CANCER (2015)

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Review Genetics & Heredity

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

Jian Zhang et al.

GENOMICS PROTEOMICS & BIOINFORMATICS (2015)

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Article Orthopedics

The role of microRNAs in cellular senescence and age-related conditions of cartilage and bone

Sylvia Weilner et al.

ACTA ORTHOPAEDICA (2015)

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Article Gastroenterology & Hepatology

Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis

Carlos J. Pirola et al.

GUT (2015)

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Article Biochemistry & Molecular Biology

STIM1, a direct target of microRNA-185, promotes tumor metastasis and is associated with poor prognosis in colorectal cancer

Z. Zhang et al.

ONCOGENE (2015)

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Article Multidisciplinary Sciences

MicroRNA-185 Targets SOCS3 to Inhibit Beta-Cell Dysfunction in Diabetes

Lidao Bao et al.

PLOS ONE (2015)

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Review Neurosciences

miRNAs: Key Players in Neurodegenerative Disorders and Epilepsy

Hanuma Kumar Karnati et al.

JOURNAL OF ALZHEIMERS DISEASE (2015)

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Article Cell Biology

Genome-wide profiling of the microRNA-mRNA regulatory network in skeletal muscle with aging

Ji Young Kim et al.

AGING-US (2014)

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Article Pathology

miR-185 Inhibits Hepatocellular Carcinoma Growth by Targeting the DNMT1/PTEN/Akt Pathway

Ximena V. Qadir et al.

AMERICAN JOURNAL OF PATHOLOGY (2014)

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Meeting Abstract Oncology

Circulating microRNA expression profile: miR-1246 and miR-185 profile as a novel diagnostic biomarker for melanoma

Virginie Armand-Labit et al.

CANCER RESEARCH (2014)

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Article Oncology

miR-185-3p regulates nasopharyngeal carcinoma radioresistance by targeting WNT2B in vitro

Guo Li et al.

CANCER SCIENCE (2014)

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Review Chemistry, Multidisciplinary

Molecular plasmonics for nanoscale spectroscopy

Matthew D. Sonntag et al.

CHEMICAL SOCIETY REVIEWS (2014)

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Review Pathology

The potential of miRNAs as biomarkers for multiple myeloma

Alberto Rocci et al.

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2014)

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Article Biochemistry & Molecular Biology

Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake

Muhua Yang et al.

JOURNAL OF LIPID RESEARCH (2014)

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Article Cell Biology

miR-185 is an independent prognosis factor and suppresses tumor metastasis in gastric cancer

Zhiqin Tan et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2014)

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Article Biochemistry & Molecular Biology

MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine

Y. Xiang et al.

ONCOGENE (2014)

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Article Gastroenterology & Hepatology

MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease

Xiao-Chen Wang et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

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Article Oncology

Combined epithelial-mesenchymal transition with cancer stem cell-like marker as predictors of recurrence after radical resection for gastric cancer

Gui-fang Xu et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2014)

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Article Cell Biology

MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain

Q. Li et al.

CELL DEATH & DISEASE (2014)

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Review Biotechnology & Applied Microbiology

The Role of MicroRNAs in Ovarian Cancer

Yasuto Kinose et al.

BIOMED RESEARCH INTERNATIONAL (2014)

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Review Cell Biology

MicroRNAs linking inflamm-aging, cellular senescence and cancer

Fabiola Olivieri et al.

AGEING RESEARCH REVIEWS (2013)

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Article Biochemistry & Molecular Biology

Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion

Bin Xu et al.

CELL (2013)

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Article Immunology

Signature MicroRNA expression patterns identified in humans with 22q11.2 deletion/DiGeorge syndrome

M. Teresa de la Morena et al.

CLINICAL IMMUNOLOGY (2013)

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Review Allergy

Epigenetics in Immune-Mediated Pulmonary Diseases

Yu Liu et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2013)

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Article Oncology

MicroRNA-324-3p regulates nasopharyngeal carcinoma radioresistance by directly targeting WNT2B

Guo Li et al.

EUROPEAN JOURNAL OF CANCER (2013)

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Article Biochemistry & Molecular Biology

A Cancer-Indicative microRNA Pattern in Normal Prostate Tissue

Olaf J. C. Hellwinkel et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

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Review Biochemistry & Molecular Biology

Non-Coding RNAs: Functional Aspects and Diagnostic Utility in Oncology

Taiho Kim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

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Article Cell Biology

MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor

Fajun Qu et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2013)

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Article Oncology

Rab25 Is a Tumor Suppressor Gene with Antiangiogenic and Anti-Invasive Activities in Esophageal Squamous Cell Carcinoma

Man Tong et al.

CANCER RESEARCH (2012)

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Review Cardiac & Cardiovascular Systems

Role of microRNAs in diabetes and its cardiovascular complications

Saran Shantikumar et al.

CARDIOVASCULAR RESEARCH (2012)

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Article Allergy

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

Guiquan Jia et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

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Review Oncology

Cancer biomarkers

N. Lynn Henry et al.

MOLECULAR ONCOLOGY (2012)

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Review Oncology

MicroRNAs in acute leukemia: from biological players to clinical contributors

D. Schotte et al.

LEUKEMIA (2012)

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Review Genetics & Heredity

The Human Transcriptome: An Unfinished Story

Mihaela Pertea

GENES (2012)

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Article Biochemistry & Molecular Biology

Inhibitory Smad7: Emerging Roles in Health and Disease

Marco A. Briones-Orta et al.

Current Molecular Pharmacology (2012)

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Article Psychiatry

Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications

Douglas F. Levinson et al.

AMERICAN JOURNAL OF PSYCHIATRY (2011)

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Article Hematology

MicroRNA Modulation of Cholesterol Homeostasis

Carlos Fernandez-Hernando et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)

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Article Neurosciences

Upregulation of Dicer and MicroRNA Expression in the Dorsolateral Prefrontal Cortex Brodmann Area 46 in Schizophrenia

Danielle M. Santarelli et al.

BIOLOGICAL PSYCHIATRY (2011)

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Article Oncology

miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells

Ming Liu et al.

CANCER LETTERS (2011)

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Article Oncology

Systematic Analysis of MicroRNAs Targeting the Androgen Receptor in Prostate Cancer Cells

Paivi Ostling et al.

CANCER RESEARCH (2011)

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Article Multidisciplinary Sciences

Regulation of Cancer Aggressive Features in Melanoma Cells by MicroRNAs

Eyal Greenberg et al.

PLOS ONE (2011)

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Review Oncology

'Omic approaches to preventing or managing metastatic breast cancer

Obi L. Griffith et al.

BREAST CANCER RESEARCH (2011)

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Article Neurosciences

Altered Cortical CDC42 Signaling Pathways in Schizophrenia: Implications for Dendritic Spine Deficits

Masayuki Ide et al.

BIOLOGICAL PSYCHIATRY (2010)

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Article Mathematical & Computational Biology

Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma

Huiqing Liu et al.

BMC SYSTEMS BIOLOGY (2010)

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Article Biochemistry & Molecular Biology

Schizophrenia is associated with an increase in cortical microRNA biogenesis

N. J. Beveridge et al.

MOLECULAR PSYCHIATRY (2010)

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Article Biochemistry & Molecular Biology

MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers

J. S. Imam et al.

ONCOGENE (2010)

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Review Cardiac & Cardiovascular Systems

MicroRNAs As Novel Regulators of Angiogenesis

Yajaira Suarez et al.

CIRCULATION RESEARCH (2009)

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Article Biochemistry & Molecular Biology

Most mammalian mRNAs are conserved targets of microRNAs

Robin C. Friedman et al.

GENOME RESEARCH (2009)

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Review Medicine, General & Internal

Gastric cancer

Henk H. Hartgrink et al.

LANCET (2009)

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Article Oncology

A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

Siew Wee Chan et al.

CANCER RESEARCH (2008)

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Article Cell Biology

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Xi Chen et al.

CELL RESEARCH (2008)

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Article Oncology

MicroRNAs and their target messenger RNAs associated with endometrial carcinogenesis

Todd Boren et al.

GYNECOLOGIC ONCOLOGY (2008)

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Article Genetics & Heredity

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

Kimberly L. Stark et al.

NATURE GENETICS (2008)

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Article Multidisciplinary Sciences

Serum MicroRNAs Are Promising Novel Biomarkers

Shlomit Gilad et al.

PLOS ONE (2008)

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Article Oncology

Micro-RNA profiling in kidney and bladder cancers

Fedra Gottardo et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2007)

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Article Hematology

MicroRNA expression profiling during human cord blood-derived CD34 cell erythropoiesis

Meng Ling Choong et al.

EXPERIMENTAL HEMATOLOGY (2007)

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Review Peripheral Vascular Disease

Angiogenesis in cancer

Naoyo Nishida et al.

VASCULAR HEALTH AND RISK MANAGEMENT (2006)

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Review Genetics & Heredity

Nasopharyngeal carcinoma

Bernadette Brennan

ORPHANET JOURNAL OF RARE DISEASES (2006)

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Article Biochemistry & Molecular Biology

Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia

J. J. Hill et al.

MOLECULAR PSYCHIATRY (2006)

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Review Oncology

Radiosensitizers in cervical cancer. Cisplatin and beyond

Myrna Candelaria et al.

RADIATION ONCOLOGY (2006)

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Article Cell Biology

The role of the androgen receptor in the development of prostatic hyperplasia and prostate cancer

B Chatterjee

MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)

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Review Cardiac & Cardiovascular Systems

Angiogenesis: basic pathophysiology and implications for disease

DC Felmeden et al.

EUROPEAN HEART JOURNAL (2003)

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Article Geriatrics & Gerontology

Frailty in older adults: Evidence for a phenotype

LP Fried et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)

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Article Endocrinology & Metabolism

Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes

JN Clore et al.

DIABETES (2000)

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