4.1 Article

Future Directions in the Treatment of Thyroid and Parathyroid Disease

Journal

OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA
Volume 57, Issue 1, Pages 155-170

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.otc.2023.07.013

Keywords

Remote access robotic surgery; Parathyroid and thyroid disease; Thermal ablation; Parathyroid autofluorescence; Artificial intelligence; Diagnostics

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Endocrine surgery has made significant advances in recent decades, expanding surgical and nonsurgical techniques. The use of newer generation robotics allows for more flexibility and better tactile feedback. Autofluorescence technology shows promise in identifying parathyroid glands and reducing the risk of hypoparathyroidism. Future research will incorporate artificial intelligence to improve preoperative assessment and intraoperative decision-making.
Endocrine surgery has made significant advances during the past several decades and continues to expand the surgical and nonsurgical techniques. Remote access thyroid and parathyroid surgery continues to push the boundaries of what can be done with the overall goal of improving the quality of patient care. Newer generation robotics are less cumbersome and easier to navigate in small cavities while attempting to recreate a sense of tactile feedback which is found in open surgery. The autofluor-escence technology for identifying parathyroid glands is promising for reducing the rate of temporary and perhaps permanent hypoparathyroidism. Quantifying autofluor-escence intraoperatively will likely become automated with AI whereby different emis-sion patterns will help differentiate between pathologic and normal parathyroid glands. More long-term data will emerge for various types of thermal ablation confirm-ing its oncological safety. Newer versions of the ablative techniques will incorporate recurrent nerve monitoring to ensure safety with higher temperatures. Future research will integrate AI to improve the workflow, safety, and diagnostic accuracy for preoper-ative assessment and intraoperative decision-making.

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