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p63: a crucial player in epithelial stemness regulation

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Maintaining epithelial stemness with p63

Gerry Melino et al.

SCIENCE SIGNALING (2015)

Review Biochemistry & Molecular Biology

MicroRNAs and p63 in epithelial stemness

E. Candi et al.

CELL DEATH AND DIFFERENTIATION (2015)

Article Biochemistry & Molecular Biology

p63 is a prosurvival factor in the adult mammary gland during post-lactational involution, affecting PI-MECs and ErbB2 tumorigenesis

A. R. Yallowitz et al.

CELL DEATH AND DIFFERENTIATION (2014)

Article Biochemistry & Molecular Biology

The Prostate Basal Cell (BC) Heterogeneity and the p63-Positive BC Differentiation Spectrum in Mice

Dong-Kee Lee et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2014)

Article Multidisciplinary Sciences

deltaNp63 Has a Role in Maintaining Epithelial Integrity in Airway Epithelium

Ari Jon Arason et al.

PLOS ONE (2014)

Review Multidisciplinary Sciences

STEM CELL PLASTICITY Plasticity of epithelial stem cells in tissue regeneration

Cedric Blanpain et al.

SCIENCE (2014)

Article Medicine, Research & Experimental

p53/p63/p73 in the Epidermis in Health and Disease

Vladimir A. Botchkarev et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2014)

Article Ophthalmology

Differences Between Niche Cells and Limbal Stromal Cells in Maintenance of Corneal Limbal Stem Cells

Yingli Li et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)

Article Biochemistry & Molecular Biology

Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis

N. S. Chari et al.

CELL DEATH AND DIFFERENTIATION (2013)

Article Cell Biology

Wnt signaling in stem and cancer stem cells

Jane D. Holland et al.

CURRENT OPINION IN CELL BIOLOGY (2013)

Article Developmental Biology

Notch signaling represses p63 expression in the developing surface ectoderm

Ana Mafalda Baptista Tadeu et al.

DEVELOPMENT (2013)

Article Medicine, Research & Experimental

Type 2 alveolar cells are stem cells in adult lung

Christina E. Barkauskas et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Biochemistry & Molecular Biology

FANCD2 Activates Transcription of TAp63 and Suppresses Tumorigenesis

Eunmi Park et al.

MOLECULAR CELL (2013)

Article Multidisciplinary Sciences

Control of somatic tissue differentiation by the long non-coding RNA TINCR

Markus Kretz et al.

NATURE (2013)

Review Cell Biology

The mechanisms of Hedgehog signalling and its roles in development and disease

James Briscoe et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

PIR2/Rnf144B regulates epithelial homeostasis by mediating degradation of p21WAF1 and p63

F. Conforti et al.

ONCOGENE (2013)

Article Multidisciplinary Sciences

p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia

Jean-Christophe Pignon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Oncology

p63 Cytoplasmic Aberrance is Associated with High Prostate Cancer Stem Cell Expression

Paranita Ferronika et al.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2012)

Article Oncology

Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty

Jeffrey A. Magee et al.

CANCER CELL (2012)

Review Cell & Tissue Engineering

Cancer Stem Cells: Current Status and Evolving Complexities

Jane E. Visvader et al.

CELL STEM CELL (2012)

Review Cell Biology

Mutant p53: one name, many proteins

William A. Freed-Pastor et al.

GENES & DEVELOPMENT (2012)

Article Multidisciplinary Sciences

p63-microRNA feedback in keratinocyte senescence

Pia Rivetti di Val Cervo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Oncology

Cancer stem cells: an evolving concept

Long V. Nguyen et al.

NATURE REVIEWS CANCER (2012)

Article Biochemistry & Molecular Biology

ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis

R. Shalom-Feuerstein et al.

CELL DEATH AND DIFFERENTIATION (2011)

Article Biochemistry & Molecular Biology

iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia

Anissa Chikh et al.

EMBO JOURNAL (2011)

Review Pathology

p63 in Epithelial Survival, Germ Cell Surveillance, and Neoplasia

Christopher P. Crum et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)

Article Biochemistry & Molecular Biology

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

Oe Yalcin-Ozuysal et al.

CELL DEATH AND DIFFERENTIATION (2010)

Article Biochemistry & Molecular Biology

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

Maddalena Adorno et al.

Editorial Material Cell & Tissue Engineering

SKP-ing TAp63: Stem Cell Depletion, Senescence, and Premature Aging

Veronica G. Beaudry et al.

CELL STEM CELL (2009)

Article Cell & Tissue Engineering

TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance

Xiaohua Su et al.

CELL STEM CELL (2009)

Article Biochemistry & Molecular Biology

Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf

Xiaohua Su et al.

EMBO JOURNAL (2009)

Article Cell Biology

TAp63 induces senescence and suppresses tumorigenesis in vivo

Xuecui Guo et al.

NATURE CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Identification and functional characterization of two new transcriptional variants of the human p63 gene

Marina Mangiulli et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Immunology

Hair Stem Cells for Bladder Regeneration in Rats: Preliminary Results

T. Drewa et al.

TRANSPLANTATION PROCEEDINGS (2009)

Article Biochemistry & Molecular Biology

miR-203 represses 'stemness' by repressing ΔNp63

A. M. Lena et al.

CELL DEATH AND DIFFERENTIATION (2008)

Article Cell & Tissue Engineering

Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment

Toula Bouras et al.

CELL STEM CELL (2008)

Review Biochemistry & Molecular Biology

p63 in prostate biology and pathology

Chiara Grisanzio et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2008)

Article Multidisciplinary Sciences

A skin microRNA promotes differentiation by repressing 'stemness'

Rui Yi et al.

NATURE (2008)

Article Biochemistry & Molecular Biology

p63: Defining roles in morphogenesis, homeostasis, and neoplasia of the epidermis

Kathryn E. King et al.

MOLECULAR CARCINOGENESIS (2007)

Article Multidisciplinary Sciences

ΔNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2

Eleonora Candi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

p63 is essential for the proliferative potential of stem cells in stratified epithelia

Makoto Senoo et al.

Article Multidisciplinary Sciences

p63 induces key target genes required for epidermal morphogenesis

Maranke I. Koster et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Cell Biology

p63 in skin appendage development

Marja L. Mikkola

CELL CYCLE (2007)

Article Multidisciplinary Sciences

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

M. E. Prince et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

p63 protects the female germ line during meiotic arrest

Eun-Kyung Suh et al.

NATURE (2006)

Article Cell Biology

p63 is upstream of IKKα in epidermal development

Eleonora Candi et al.

JOURNAL OF CELL SCIENCE (2006)

Article Cell Biology

p63 regulates an adhesion programme and cell survival in epithelial cells

Danielle K. Carroll et al.

NATURE CELL BIOLOGY (2006)

Article Cell Biology

Defining cell lineages in the prostate epithelium

S Signoretti et al.

CELL CYCLE (2006)

Review Biochemistry & Molecular Biology

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress

F. Murray-Zmijewski et al.

CELL DEATH AND DIFFERENTIATION (2006)

Article Dermatology

p63 deficiency: A failure of lineage commitment or stem cell maintenance?

MI Koster et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS (2005)

Article Dermatology

Expression of beta-catenin, p63 and CD34 in hair follicles during the course of androgenetic alopecia

M Fiuraskova et al.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2005)

Article Ophthalmology

Regulation of limbal keratinocyte proliferation and differentiation by TAp63 and ΔNp63 transcription factors

DY Wang et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)

Article Multidisciplinary Sciences

p63 regulates commitment to the prostate cell lineage

S Signoretti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Multidisciplinary Sciences

Isoforms of ΔNp63 and the migration of ocular limbal cells in human corneal regeneration

E Di Iorio et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Dermatology

The role of p63 in development and differentiation of the epidermis

MI Kostera et al.

JOURNAL OF DERMATOLOGICAL SCIENCE (2004)

Article Biochemistry & Molecular Biology

p51/p63 controls subunit α3 of the major epidermis integrin anchoring the stem cells to the niche

S Kurata et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Immunology

Ubiquitin-dependent degradation of p73 is inhibited by PML

F Bernassola et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Review Cell Biology

p63 and epithelial appendage development

MI Koster et al.

DIFFERENTIATION (2004)

Article Critical Care Medicine

Role of P63 amplification and overexpression in lung cancer development

PP Massion et al.

CHEST (2004)

Article Biochemistry & Molecular Biology

The corneal epithelial stem cell

JE Moore et al.

DNA AND CELL BIOLOGY (2002)

Article Multidisciplinary Sciences

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

ER Flores et al.

NATURE (2002)

Article Cell Biology

Cell differentiation lineage in the prostate

YZ Wang et al.

DIFFERENTIATION (2001)

Article Pathology

p63, a p53 homologue, is a selective nuclear marker of myoepithelial cells of the human breast

M Barbareschi et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2001)

Article Multidisciplinary Sciences

p63 identifies keratinocyte stem cells

G Pellegrini et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Pathology

p63 is a prostate basal cell marker and is required for prostate development

S Signoretti et al.

AMERICAN JOURNAL OF PATHOLOGY (2000)

Article Multidisciplinary Sciences

AIS is an oncogene amplified in squamous cell carcinoma

K Hibi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)