Journal
NEUROIMAGING CLINICS OF NORTH AMERICA
Volume 34, Issue 1, Pages 113-128Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nic.2023.07.003
Keywords
CNS; Vasculitis; Vasculopathy; Drug-related; Cocaine-induced; Levamisole; RCVS; PRES
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Cocaine-induced CNS vasculitis and midline destructive lesion, as well as reversible vasoconstriction syndrome triggered by substance abuse, are all important conditions that are associated with drugs and their risk factors.
center dot Cocaine-induced CNS vasculitis is produced by additives/contaminants added to cocaine, mainly levamisole.center dot Cocaine-induced midline destructive lesion should be considered in any structural lesion of the si-nonasal complex in the context of a positive toxicologic screening or confirmed cocaine-snorting habit.center dot Marijuana is the most prevalent triggering factor in reversible vasoconstriction syndrome secondary to substance abuse.center dot The risk of CNS vasculopathy associated with sympathomimetic or immunosuppressant drug ther-apy increases in patients with impaired renal and hepatic function.
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