☆ 4.6 Article

pH-Weighted amine chemical exchange saturation transfer echo planar imaging visualizes infiltrating glioblastoma cells

NEURO-ONCOLOGY (2023)

Related references

Note: Only part of the references are listed.

Article Radiology, Nuclear Medicine & Medical Imaging

Radiomics-based evaluation and possible characterization of dynamic contrast enhanced (DCE) perfusion derived different sub-regions of Glioblastoma

Suhail Parvaze et al.

Summary: This study aims to characterize different tumor sub-regions derived from DCE perfusion MRI using routine 3D post-contrast-T1 (T1GD) and FLAIR images with the aid of Radiomics analysis. The results showed that Radiomics-based specific feature values and maps help to differentiate different tumor sub-regions. However, the GLDM_DependenceNonUniformity feature appears to be most specific for separating edema from the remaining tumor sub-regions using conventional FLAIR images.

EUROPEAN JOURNAL OF RADIOLOGY (2023)

Add to Collection

Article Biophysics

Amine-weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors

Nicholas S. Cho et al.

Summary: Amine-weighted CEST MRI is a valuable imaging technique for brain tumors, sensitive to changes in amino acids and pH, and has the potential to greatly impact patients by understanding vulnerabilities in the tumor microenvironment and providing complementary value to conventional and exploratory therapies.

NMR IN BIOMEDICINE (2023)

Add to Collection

Article Oncology

Metabolic delineation of IDH1 wild-type glioblastoma surgical anatomy: how to plan the tumor extent of resection

Roberto Altieri et al.

Summary: The purpose of this study was to determine the correlation between anatomical and metabolic data and investigate the role of (11)C-methionine positron emission tomography ((11)[C]-MET PET) in providing additional information for preoperative planning of glioblastoma surgery. The study found a significant correlation between preoperative metabolic data and tumor volume. Therefore, (11)[C]-MET PET should be considered in surgical planning to achieve a Supra Total Resection (SupTR).

JOURNAL OF NEURO-ONCOLOGY (2023)

Add to Collection

Review Oncology

Conventional and Advanced Magnetic Resonance Imaging Assessment of Non-Enhancing Peritumoral Area in Brain Tumor

Elisa Scola et al.

Summary: The non-enhancing peritumoral area (NEPA) is defined as the hyperintense region in T2-weighted and fluid-attenuated inversion recovery (FLAIR) images surrounding a brain tumor. NEPA analyses using conventional and advanced MRI techniques have shown promise in the differential diagnosis of brain tumors and predicting prognosis and treatment response. An update on this topic is needed due to the rapid technological advancements in advanced MRI imaging.

CANCERS (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Novel 3D magnetic resonance fingerprinting radiomics in adult brain tumors: a feasibility study

Charit Tippareddy et al.

Summary: This study aimed to test the feasibility of using 3D MRF maps with radiomics analysis and machine learning in the characterization of adult brain intra-axial neoplasms. The results showed that MRF maps were able to differentiate tumors based on type, grade, and IDH1 status. Furthermore, the radiomics features of MRF maps can also characterize gliomas based on grade, IDH1 status, and survival.

EUROPEAN RADIOLOGY (2023)

Add to Collection

Article Oncology

A consensus definition of supratotal resection for anatomically distinct primary glioblastoma: an AANS/CNS Section on Tumors survey of neurosurgical oncologists

Maureen Rakovec et al.

Summary: There is a lack of consensus on the definition and appropriate use of Supratotal resection (SpTR) of glioblastoma. A survey was conducted among neurosurgical oncologists to gather opinions on the definition and potential clinical trial candidates for SpTR. The majority of neurosurgeons surveyed agreed on the definitions of SpTR as complete resection with removal of some non-contrast enhancement or resection 1-2 cm beyond contrast enhancement. Right anterior temporal and right frontal glioblastomas were identified as the most suitable candidates for clinical trials.

JOURNAL OF NEURO-ONCOLOGY (2022)

Add to Collection

Article Oncology

Three-Dimensional Arterial Spin Labeling-Guided Sub-Volume Segmentation of Radiotherapy in Adult Non-Enhancing Low-Grade Gliomas

Zihong Zhu et al.

Summary: This study evaluated the feasibility of sub-volume segmentation for radiotherapy planning of adult non-enhancing low-grade gliomas (NE-LGGs) guided by three-dimensional arterial spin labeling (3D-ASL). The differences in high- and low-perfusion areas of NE-LGGs were analyzed using multi-sequence magnetic resonance imaging (MRI) radiomics. The results showed that 3D-ASL can guide the radiotherapy planning for NE-LGGs.

FRONTIERS IN ONCOLOGY (2022)

Add to Collection

Article Oncology

Relapse patterns and radiation dose exposure in IDH wild-type glioblastoma at first radiographic recurrence following chemoradiation

Satoka Shidoh et al.

Summary: The purpose of this study was to investigate the radiation dose distribution and lesion morphometry in patients with glioblastoma. The study found that most GBMs recur within the therapeutic radiation doses, and tumors with longer progression-free survival were located further from the original tumor and had a more solid and/or nodular morphology.

JOURNAL OF NEURO-ONCOLOGY (2022)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Influence of phosphate concentration on amine, amide, and hydroxyl CEST contrast

Jingwen Yao et al.

Summary: The study found that the exchange rates of alpha-amine and hydroxyl protons are highly dependent on pH and phosphate concentrations, while the exchange rates of eta-amine and amide protons depend on pH but are not catalyzed by phosphate. Phosphate, predominantly intracellular, affects the CEST contrast of alpha-amine, showing higher sensitivity to changes in the extracellular microenvironment.

MAGNETIC RESONANCE IN MEDICINE (2021)

Add to Collection

Review Oncology

The blood-tumour barrier in cancer biology and therapy

Patricia S. Steeg

Summary: The blood-brain barrier plays a crucial role in maintaining normal brain function, but modifications in primary brain tumors and brain metastases result in the blood-tumor barrier, further limiting the penetration of therapeutic agents. This challenge highlights the importance of understanding and overcoming the structural and functional complexities of the blood-tumor barrier for improving cancer therapy and patient outcomes.

NATURE REVIEWS CLINICAL ONCOLOGY (2021)

Add to Collection

Review Oncology

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

David N. Louis et al.

Summary: The fifth edition of the WHO Classification of Tumors of the Central Nervous System integrates molecular diagnostics into CNS tumor classification, introduces different approaches to tumor nomenclature and grading, and emphasizes the importance of integrated diagnoses and layered reports.

NEURO-ONCOLOGY (2021)

Add to Collection

Article Multidisciplinary Sciences

Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma

Trang T. T. Nguyen et al.

Summary: The inhibition of AURKA can lead to metabolic reprogramming in glioblastoma cells, enhancing mitochondrial activity, and inhibiting oxidative metabolism can sensitize the cells. Combining AURKA inhibitors with FAO inhibitors extends overall survival in GBM models.

NATURE COMMUNICATIONS (2021)

Add to Collection

Review Cell Biology

Metabolic Drivers of Invasion in Glioblastoma

Joseph H. Garcia et al.

Summary: Glioblastoma is a deadly brain tumor with poor prognosis largely due to cellular invasion and metabolic adaptations. Recent studies have shown that metabolic reprogramming plays a role in GBM invasion and may offer novel therapeutic targets.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Add to Collection

Letter Clinical Neurology

Repeated Gamma Knife radiosurgery for recurrent trigeminal neuralgia: is it the next over-the-counter treatment?

Manjul Tripathi

JOURNAL OF NEUROSURGERY (2021)

Add to Collection

Article Neuroimaging

Aerobic glycolytic imaging of human gliomas using combined pH-, oxygen-, and perfusion-weighted magnetic resonance imaging

Akifumi Hagiwara et al.

Summary: The study quantified abnormal metabolism of diffuse gliomas using aerobic glycolytic imaging, finding significantly lower aerobic glycolytic index (AGI) in IDH mutant gliomas than wild-type, and strong correlations between AGI and glucose metabolism and key glycolytic protein expression.

NEUROIMAGE-CLINICAL (2021)

Add to Collection

Article Oncology

MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in Glioblastoma

Yiru Zhang et al.

CANCER RESEARCH (2020)

Add to Collection

Review Biochemistry & Molecular Biology

Approaches to PET Imaging of Glioblastoma

Lindsey R. Drake et al.

MOLECULES (2020)

Add to Collection

Article Oncology

Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma

Annette M. Molinaro et al.

JAMA ONCOLOGY (2020)

Add to Collection

Review Biochemistry & Molecular Biology

Tumor Cell Invasion in Glioblastoma

Arabel Vollmann-Zwerenz et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection

Article Clinical Neurology

Diffusion Magnetic Resonance Imaging Phenotypes Predict Overall Survival Benefit From Bevacizumab or Surgery in Recurrent Glioblastoma With Large Tumor Burden

Kunal S. Patel et al.

NEUROSURGERY (2020)

Add to Collection

Review Oncology

Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas

Jerrold L. Boxerman et al.

NEURO-ONCOLOGY (2020)

Add to Collection

Article Multidisciplinary Sciences

Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study

Jingwen Yao et al.

SCIENTIFIC REPORTS (2020)

Add to Collection

Article Multidisciplinary Sciences

Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma

Kunal S. Patel et al.

SCIENTIFIC REPORTS (2020)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Reproducibility analysis of multi-institutional paired expert annotations and radiomic features of the Ivy Glioblastoma Atlas Project (Ivy GAP) dataset

Sarthak Pati et al.

MEDICAL PHYSICS (2020)

Add to Collection

Article Oncology

pH-weighted amine chemical exchange saturation transfer echoplanar imaging (CEST-EPI) as a potential early biomarker for bevacizumab failure in recurrent glioblastoma

Jingwen Yao et al.

JOURNAL OF NEURO-ONCOLOGY (2019)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region

A. Vallatos et al.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2019)

Add to Collection

Review Oncology

Evidence and context of use for contrast enhancement as a surrogate of disease burden and treatment response in malignant glioma

Benjamin M. Ellingson et al.

NEURO-ONCOLOGY (2018)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI)

Robert J. Harris et al.

MAGNETIC RESONANCE IN MEDICINE (2018)

Add to Collection

Article Oncology

Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma

Benjamin M. Ellingson et al.

NEURO-ONCOLOGY (2018)

Add to Collection

Article Multidisciplinary Sciences

Retrospective Analysis of Radiological Recurrence Patterns in Glioblastoma, Their Prognostic Value And Association to Postoperative Infarct Volume

Stefanie Bette et al.

SCIENTIFIC REPORTS (2018)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Diagnostic value of apparent diffusion coefficient in differentiating between high-grade gliomas and brain metastases

Ionut Caravan et al.

ACTA RADIOLOGICA (2018)

Add to Collection

Article Oncology

Baseline pretreatment contrast enhancing tumor volume including central necrosis is a prognostic factor in recurrent glioblastoma: evidence from single- and multicenter trials

Benjamin M. Ellingson et al.

NEURO-ONCOLOGY (2017)

Add to Collection

Article Oncology

Impact of removed tumor volume and location on patient outcome in glioblastoma

Al-Wala Awad et al.

JOURNAL OF NEURO-ONCOLOGY (2017)

Add to Collection

Article Multidisciplinary Sciences

QuPath: Open source software for digital pathology image analysis

Peter Bankhead et al.

SCIENTIFIC REPORTS (2017)

Add to Collection

Article Oncology

Radiotherapy in Glioblastoma: the Past, the Present and the Future

C. Gzell et al.

CLINICAL ONCOLOGY (2017)

Add to Collection

Article Biophysics

Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST-EPI) in glioma at 3T

Robert J. Harris et al.

NMR IN BIOMEDICINE (2016)

Add to Collection

Review Oncology

Association of the Extent of Resection With Survival in Glioblastoma A Systematic Review and Meta-analysis

Timothy J. Brown et al.

JAMA ONCOLOGY (2016)

Add to Collection

Review Oncology

Mechanisms regulating glioma invasion

Ivy Paw et al.

CANCER LETTERS (2015)

Add to Collection

Article Oncology

pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI

Robert J. Harris et al.

NEURO-ONCOLOGY (2015)

Add to Collection

Article Clinical Neurology

Utility of Diffusion Tensor Imaging in Evaluation of the Peritumoral Region in Patients with Primary and Metastatic Brain Tumors

E. J. Sternberg et al.

AMERICAN JOURNAL OF NEURORADIOLOGY (2014)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Recurrent Glioblastoma Treated with Bevacizumab: Contrast-enhanced T1-weighted Subtraction Maps Improve Tumor Delineation and Aid Prediction of Survival in a Multicenter Clinical Trial

Benjamin M. Ellingson et al.

RADIOLOGY (2014)

Add to Collection

Article Biochemistry & Molecular Biology

Reversing the Warburg Effect as a Treatment for Glioblastoma

Ethan Poteet et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Add to Collection

Article Oncology

Identifying the mesenchymal molecular subtype of glioblastoma using quantitative volumetric analysis of anatomic magnetic resonance images

Kourosh M. Naeini et al.

NEURO-ONCOLOGY (2013)

Add to Collection

Article Clinical Neurology

Metabolic findings on 3T 1H-MR Spectroscopy in peritumoral brain edema

R. Ricci et al.

AMERICAN JOURNAL OF NEURORADIOLOGY (2007)

Add to Collection

Article Medicine, General & Internal

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

R Stupp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

High-field proton MRS of human brain

A Di Costanzo et al.

EUROPEAN JOURNAL OF RADIOLOGY (2003)

Add to Collection

© Peeref 2019-2024. All rights reserved.