A new endometrial organoid: synthetically engineered matrix enhances epithelial-stromal interactions

Over the past decade, the focus on modelling the human endometrium and its cyclical transformations has intensified, driven in part by the lack of notable progress in treating endometrial diseases. Gnecco and collaborators now unveil a cutting-edge endometrial organoid culture using synthetic hydrogels with endometrial niche peptides and epithelial and stromal cells.

Automated summary

Over the past decade, there has been increased focus on modeling the human endometrium and its cyclical transformations, driven by the lack of significant progress in treating endometrial diseases. Gnecco and collaborators have now introduced a cutting-edge endometrial organoid culture using synthetic hydrogels with endometrial niche peptides and epithelial and stromal cells.