Ironman training for NK cells

IRF4 is required for the differentiation of T cells, B cells and some myeloid cells. A new study finds that IRF4 is upregulated following natural killer (NK) cell activation and is required for the differentiation and expansion of virus-specific NK cells by controlling nutrient acquisition, including iron uptake.

Automated summary

IRF4 is necessary for the differentiation of T cells, B cells, and some myeloid cells. A recent study reveals that IRF4 is upregulated after natural killer (NK) cell activation and is essential for the differentiation and expansion of virus-specific NK cells by regulating nutrient acquisition, including iron uptake.