4.8 Editorial Material

Viruses trick bystander cells into lowering their defences

Journal

NATURE
Volume 619, Issue 7968, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/d41586-023-02135-1

Keywords

Virology; Microbiology; Medical research

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The microenvironment of virus-infected cells and uninfected adjacent cells plays a role in infection. Human cytomegalovirus suppresses the immune response of neighboring uninfected cells, while distant cells can mount an antiviral defense. This raises the question of how the cellular microenvironment influences viral infection.
The microenvironment of virus-infected cells and uninfected adjacent cells influences infection. Human cytomegalovirus dampens the immune response of neighbouring uninfected cells, but distant cells can mount an antiviral defence. How the cellular microenvironment influences viral infection.

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