☆ 4.4 Article

Anti-diabetic and anti-urease potential of Osbeckia nutans Wall. leaves

NATURAL PRODUCT RESEARCH (2023)

Related references

Note: Only part of the references are listed.
Article Chemistry, Applied

Phenolic compounds of Zanthoxylum armatum DC as potential inhibitors of urease and SARS-CoV2 using molecular docking approach and with simulation study

Nilamoni Chelleng et al.

Summary: This study evaluated the anti-urease effects of extracts and phenolic compounds from Zanthoxylum armatum leaves. Chlorogenic acid showed significant interactions with H. pylori urease and SARS-CoV2 vital proteins, while gallic acid interacted with spike proteins of SARS-CoV2. The findings suggest that chlorogenic acid could be a significant antagonist of H. pylori urease.

NATURAL PRODUCT RESEARCH (2023)

Add to Collection
Article Microbiology

Preparation, urease inhibition mechanisms, and anti-Helicobacter pylori activities of hesperetin-7-rhamnoglucoside

Mohamed Sharaf et al.

Summary: This study investigated the effects of a bioflavonoid called hesperetin-7-rhamnoglucoside, isolated from citrus fruit peel, on Helicobacter pylori. The study found that hesperetin-7-rhamnoglucoside inhibited the activity of urease, an enzyme produced by H. pylori, by interacting with the bacterial cells and causing membrane disruption. Molecular docking and molecular dynamics simulations revealed the mechanisms through which hesperetin-7-rhamnoglucoside inhibits the target protein. This study presents new potential anti-H. pylori agents derived from natural sources.

CURRENT RESEARCH IN MICROBIAL SCIENCES (2022)

Add to Collection
Review Biochemistry & Molecular Biology

Trends in insulin resistance: insights into mechanisms and therapeutic strategy

Mengwei Li et al.

Summary: The centenary of insulin discovery provides an important opportunity to transform diabetes from a fatal diagnosis to a manageable chronic condition. Insulin resistance, associated with obesity, diabetes, and other abnormalities, is caused by abnormal biological response to insulin stimulation. Recent studies suggest that dysregulated metabolic mediators released by adipose tissue contribute to insulin resistance. Although there is no specific medication for insulin resistance, lifestyle changes and pharmacological interventions have been used to improve insulin sensitivity.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

Add to Collection
Article Chemistry, Multidisciplinary

Antidiabetic Activity of Ficusonolide, a Triterpene Lactone from Ficus foveolata (Wall. ex Miq.): In Vitro, In Vivo, and In Silico Approaches

Ala Ud Din et al.

Summary: The research suggests that ficusonolide from Ficus foveolata has potential antidiabetic activity by enhancing glucose uptake and significantly reducing hyperglycemia in diabetic rats. Additionally, ficusonolide displayed inhibitory activity against key proteins involved in diabetes, indicating a possible mechanism for its antidiabetic effects.

ACS OMEGA (2021)

Add to Collection
Article Agriculture, Multidisciplinary

New Insights into the Inhibition Mechanism of Betulinic Acid on alpha-Glucosidase

Huafang Ding et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Add to Collection
Review Biochemistry & Molecular Biology

Action of Phytochemicals on Insulin Signaling Pathways Accelerating Glucose Transporter (GLUT4) Protein Translocation

Abu Sadat Md Sayem et al.

MOLECULES (2018)

Add to Collection
Review Cell Biology

H. pylori infection and extra-gastroduodenal diseases

Feng-Woei Tsay et al.

JOURNAL OF BIOMEDICAL SCIENCE (2018)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.