Journal
MOLECULAR NEUROBIOLOGY
Volume 54, Issue 9, Pages 6750-6761Publisher
HUMANA PRESS INC
DOI: 10.1007/s12035-016-0195-6
Keywords
Ischemic stroke; Sensorimotor; Cognitive; Behavioral; Rodents
Categories
Ask authors/readers for more resources
Despite years of research, most preclinical trials on ischemic stroke have remained unsuccessful owing to poor methodological and statistical standards leading to translational roadblocks. Various behavioral tests have been established to evaluate traits such as sensorimotor function, cognitive and social interactions, and anxiety-like and depression-like behavior. A test's validity is of cardinal importance as it influences the chance of a successful translation of preclinical results to clinical settings. The mission of choosing a behavioral test for a particular project is, therefore, imperative and the present review aims to provide a structured way to evaluate rodent behavioral tests with implications in ischemic stroke.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available