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Spleen-targeted nanosystems for immunomodulation

NANO TODAY (2023)

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Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes

Owen S. Fenton et al.

ADVANCED MATERIALS (2017)

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Designing Liposomes To Suppress Extracellular Matrix Expression To Enhance Drug Penetration and Pancreatic Tumor Therapy

Tianjiao Ji et al.

ACS NANO (2017)

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Tumor Microenvironment Activated Membrane Fusogenic Liposome with Speedy Antibody and Doxorubicin Delivery for Synergistic Treatment of Metastatic Tumors

Hongzhang Deng et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Dendritic cell maturation and cross-presentation: timing matters!

Andres Alloatti et al.

IMMUNOLOGICAL REVIEWS (2016)

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Specific delivery of an immunosuppressive drug to splenic B cells by antigen-modified liposomes and its antiallergic effect

Kosuke Shimizu et al.

JOURNAL OF DRUG TARGETING (2016)

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Article Multidisciplinary Sciences

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Lena M. Kranz et al.

NATURE (2016)

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Biomechanics of red blood cells in human spleen and consequences for physiology and disease

Igor V. Pivkin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

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Article Medicine, Research & Experimental

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon

Katrijn Broos et al.

Molecular Therapy-Nucleic Acids (2016)

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How Follicular Dendritic Cells Shape the B-Cell Antigenome

Jan Kranich et al.

FRONTIERS IN IMMUNOLOGY (2016)

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Enhanced and Extended Anti-Hypertensive Effect of VP5 Nanoparticles

Ting Yu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

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Splenic Gene Delivery System Using Self-assembling Nano-complex with Phosphatidylserine Analog

Tomoaki Kurosaki et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2015)

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Going beyond the liver: Progress and challenges of targeted delivery of siRNA therapeutics

Cornelia Lorenzer et al.

JOURNAL OF CONTROLLED RELEASE (2015)

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Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs

Kevin J. Kauffman et al.

NANO LETTERS (2015)

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MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

Wen Pan et al.

NATURE COMMUNICATIONS (2015)

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Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase

Kristen M. Lorentz et al.

SCIENCE ADVANCES (2015)

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Tumor-Derived Osteopontin Suppresses Antitumor Immunity by Promoting Extramedullary Myelopoiesis

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CANCER RESEARCH (2014)

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The contribution of vaccination to global health: past, present and future

Brian Greenwood

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

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Benefits and risks of splenectomy

Elroy P. Weledji

INTERNATIONAL JOURNAL OF SURGERY (2014)

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Liposomal drug delivery systems: From concept to clinical applications

Theresa M. Allen et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

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Secure Splenic Delivery of Plasmid DNA and Its Application to DNA Vaccine

Tomoaki Kurosaki et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2013)

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The Spleen in Local and Systemic Regulation of Immunity

Vincenzo Bronte et al.

IMMUNITY (2013)

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Engineering antigens for in situ erythrocyte binding induces T-cell deletion

Stephan Kontos et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Article Microbiology

Extramedullary Myelopoiesis in Malaria Depends on Mobilization of Myeloid-Restricted Progenitors by IFN-γ Induced Chemokines

Nikolai N. Belyaev et al.

PLOS PATHOGENS (2013)

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History of myeloid-derived suppressor cells

James E. Talmadge et al.

NATURE REVIEWS CANCER (2013)

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Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

S. M. Moghimi et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)

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Article Biochemistry & Molecular Biology

The location of splenic NKT cells favours their rapid activation by blood-borne antigen

Patricia Barral et al.

EMBO JOURNAL (2012)

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The RP105/MD-1 complex is indispensable for TLR4/MD-2-dependent proliferation and IgM-secreting plasma cell differentiation of marginal zone B cells

Yoshinori Nagai et al.

INTERNATIONAL IMMUNOLOGY (2012)

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The journey of a drug-carrier in the body: An anatomo-physiological perspective

Nicolas Bertrand et al.

JOURNAL OF CONTROLLED RELEASE (2012)

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Origins of tumor-associated macrophages and neutrophils

Virna Cortez-Retamozo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

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Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells

Tatiana I. Novobrantseva et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2012)

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The pathogenesis of Plasmodium falciparum malaria in humans: insights from splenic physiology

Pierre A. Buffet et al.

BLOOD (2011)

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Myeloid cell population dynamics in healthy and tumor-bearing mice

Satoshi Ueha et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2011)

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Transcription Factor Nkx2-3 Controls the Vascular Identity and Lymphocyte Homing in the Spleen

Tamas Czoempoely et al.

JOURNAL OF IMMUNOLOGY (2011)

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Myeloid-derived suppressor cells in parasitic infections

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EUROPEAN JOURNAL OF IMMUNOLOGY (2010)

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Overview of the immune response

David D. Chaplin

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)

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Marginal Zone Precursor B Cells as Cellular Agents for Type I IFN-Promoted Antigen Transport in Autoimmunity

John H. Wang et al.

JOURNAL OF IMMUNOLOGY (2010)

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Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

Akin Akinc et al.

MOLECULAR THERAPY (2010)

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CD8+T Cell Priming by Dendritic Cell Vaccines Requires Antigen Transfer to Endogenous Antigen Presenting Cells

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PLOS ONE (2010)

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Editorial Material Rheumatology

Targeted delivery of liposomal dexamethasone phosphate to the spleen provides a persistent therapeutic effect in rat antigen-induced arthritis

U. Rauchhaus et al.

ANNALS OF THE RHEUMATIC DISEASES (2009)

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Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

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SCIENCE (2009)

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Geography and plumbing control the T cell response to infection

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IMMUNOLOGY AND CELL BIOLOGY (2008)

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Factors affecting the clearance and biodistribution of polymeric nanoparticles

Frank Alexis et al.

MOLECULAR PHARMACEUTICS (2008)

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Renal clearance of quantum dots

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NATURE BIOTECHNOLOGY (2007)

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Germinal-center organization and cellular dynamics

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IMMUNITY (2007)

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Contribution of high-resolution correlative imaging techniques in the study of the liver sieve in three-dimensions

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MICROSCOPY RESEARCH AND TECHNIQUE (2007)

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Normal structure, function, and histology of the spleen

Mark F. Cesta

TOXICOLOGIC PATHOLOGY (2006)

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Structure and function of the spleen

RE Mebius et al.

NATURE REVIEWS IMMUNOLOGY (2005)

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Marginal zone B cells in lymphocyte activation and regulation

T Lopes-Carvalho et al.

CURRENT OPINION IN IMMUNOLOGY (2005)

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Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5

CDC Allen et al.

NATURE IMMUNOLOGY (2004)

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Carrier erythrocytes: An overview

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DRUG DELIVERY (2003)

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