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Engineered plant extracellular vesicles for autoimmune diseases therapy

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Microfluidic liposomes-anchored microgels as extended delivery platform for treatment of osteoarthritis

Jielai Yang et al.

CHEMICAL ENGINEERING JOURNAL (2020)

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Milk-exosome based pH/light sensitive drug system to enhance anticancer activity against oral squamous cell carcinoma

Qian Zhang et al.

RSC ADVANCES (2020)

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Exosomes in clinical trial and their production in compliance with good manufacturing practice

Yu-Shuan Chen et al.

TZU CHI MEDICAL JOURNAL (2020)

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Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells

Bethany N. Hannafon et al.

CELL COMMUNICATION AND SIGNALING (2019)

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Sinomenine mitigates collagen-induced arthritis mice by inhibiting angiogenesis

Zhi-tao Feng et al.

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Taraxasterol suppresses inflammation in IL-1β-induced rheumatoid arthritis fibroblast-like synoviocytes and rheumatoid arthritis progression in mice

Jianfeng Chen et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2019)

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Exosome-like Nanoparticles from Ginger Rhizomes Inhibited NLRP3 Inflammasome Activation

Xingyi Chen et al.

MOLECULAR PHARMACEUTICS (2019)

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Reversal of Osteoporotic Activity by Endothelial Cell-Secreted Bone Targeting and Biocompatible Exosomes

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NANO LETTERS (2019)

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Turnip Mosaic Virus Components Are Released into the Extracellular Space by Vesicles in Infected Leaves

Nooshin Movahed et al.

PLANT PHYSIOLOGY (2019)

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Advances in therapeutic applications of extracellular vesicles

Oscar P. B. Wiklander et al.

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Nanotechnology based CRISPR/Cas9 system delivery for genome editing: Progress and prospect

Huan Deng et al.

NANO RESEARCH (2019)

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Exosome-Induced Regulation in Inflammatory Bowel Disease

Huiting Zhang et al.

FRONTIERS IN IMMUNOLOGY (2019)

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Immunomodulatory effect of human umbilical cord mesenchymal stem cells on T lymphocytes in rheumatoid arthritis

Dan Ma et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2019)

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Extracellular vesicles released by ovarian carcinoma contain arginase 1 that mitigates antitumor immune response

Anna Sosnowska et al.

ONCOIMMUNOLOGY (2019)

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Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth

Meng Cao et al.

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Amelioration of regulatory T cells by Lactobacillus delbrueckii and Lactobacillus rhamnosus in pristane-induced lupus mice model

Sahar Khorasani et al.

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Internalization of Exosomes through Receptor-Mediated Endocytosis

Amber Gonda et al.

MOLECULAR CANCER RESEARCH (2019)

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Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

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NATURE CELL BIOLOGY (2019)

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Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nuts

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Plant-Derived Exosomal Nanoparticles Inhibit Pathogenicity of Porphyromonas gingivalis

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ISCIENCE (2019)

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The emerging and uncultivated potential of CRISPR technology in plant science

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NATURE PLANTS (2019)

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Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles

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SMALL (2018)

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New Technologies for Analysis of Extracellular Vesicles

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Oxymatrine prevents synovial inflammation and migration via blocking NF-κB activation in rheumatoid fibroblast-like synoviocytes

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Protein biocargo of citrus fruit-derived vesicles reveals heterogeneous transport and extracellular vesicle populations

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Advances in plant-derived edible nanoparticle-based lipid nano-drug delivery systems as therapeutic nanomedicines

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JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Arrowtail RNA for Ligand Display on Ginger Exosome-like Nanovesicles to Systemic Deliver siRNA for Cancer Suppression

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SCIENTIFIC REPORTS (2018)

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Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota

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CELL HOST & MICROBE (2018)

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Exosome-like Nanovesicles Isolated from Citrus limon L. Exert Anti-oxidative Effect

Nicola Baldini et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2018)

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Apple-Derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 261 in Caco-2 Cells

Daichi Fujita et al.

MOLECULAR PHARMACEUTICS (2018)

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Update on the epidemiology, risk factors, and disease outcomes of rheumatoid arthritis

Diane van der Woude et al.

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2018)

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Epigenetic Variability of CD4+CD25+Tregs Contributes to the Pathogenesis of Autoimmune Diseases

Ye Shu et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2017)

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Synovium-Derived MicroRNAs Regulate Bone Pathways in Rheumatoid Arthritis

Yukiko Maeda et al.

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Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase

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MOLECULAR THERAPY (2017)

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Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

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NATURE (2017)

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Extracellular Vesicles: Unique Intercellular Delivery Vehicles

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TRENDS IN CELL BIOLOGY (2017)

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Progress in Exosome Isolation Techniques

Pin Li et al.

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Bifidobacterium animalis in combination with human origin of Lactobacillus plantarum ameliorate neuroinflammation in experimental model of multiple sclerosis by altering CD4+T cell subset balance

Zohre Salehipour et al.

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Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer

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BIOMATERIALS (2016)

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Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis

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CLINICA CHIMICA ACTA (2016)

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Charge-based precipitation of extracellular vesicles

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INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)

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Emerging Frontiers in Drug Delivery

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Grapefruit-derived Nanovectors Delivering Therapeutic miR17 Through an Intranasal Route Inhibit Brain Tumor Progression

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MOLECULAR THERAPY (2016)

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Edible Ginger-derived Nano-lipids Loaded with Doxorubicin as a Novel Drug-delivery Approach for Colon Cancer Therapy

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MOLECULAR THERAPY (2016)

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Oxidative Stress Relevance in the Pathogenesis of the Rheumatoid Arthritis: A Systematic Review

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BIOMED RESEARCH INTERNATIONAL (2016)

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ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles

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SCIENTIFIC REPORTS (2016)

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Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites

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Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity

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CYTOKINE (2015)

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Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins

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Human autoimmune diseases: a comprehensive update

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Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

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NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

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Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis

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SCIENCE TRANSLATIONAL MEDICINE (2015)

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Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death

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ONCOTARGET (2015)

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Ginger-derived nanoparticles protect against alcohol-induced liver damage

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JOURNAL OF EXTRACELLULAR VESICLES (2015)

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The Role of Interleukin-17A in Psoriatic Disease

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BIODRUGS (2014)

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Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles

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MOLECULAR NUTRITION & FOOD RESEARCH (2014)

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Targeted Drug Delivery to Intestinal Macrophages by Bioactive Nanovesicles Released from Grapefruit

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MOLECULAR THERAPY (2014)

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CURRENT OPINION IN IMMUNOLOGY (2013)

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Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis

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MOLECULAR THERAPY (2013)

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Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids

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Platelets can enhance vascular permeability

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BLOOD (2012)

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Autoimmune Diseases: Early Diagnosis and New Treatment Strategies

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Celastrus and Its Bioactive Celastrol Protect against Bone Damage in Autoimmune Arthritis by Modulating Osteoimmune Cross-talk

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Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy

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FRONTIERS IN PHYSIOLOGY (2012)

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Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes

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ANNALS OF THE RHEUMATIC DISEASES (2011)

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Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

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CELL (2010)

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EXPO, an Exocyst-Positive Organelle Distinct from Multivesicular Endosomes and Autophagosomes, Mediates Cytosol to Cell Wall Exocytosis in Arabidopsis and Tobacco Cells

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PLANT CELL (2010)

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Animal models of multiple sclerosis-Potentials and limitations

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PROGRESS IN NEUROBIOLOGY (2010)

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Th17 and Natural Treg Cell Population Dynamics in Systemic Lupus Erythematosus

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ARTHRITIS AND RHEUMATISM (2009)

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The Relationship Between Intestinal Microbiota and the Central Nervous System in Normal Gastrointestinal Function and Disease

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A novel membrane fusion-mediated plant immunity against bacterial pathogens

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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NATURE (2009)

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Transdermal drug delivery

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Do Plant Cells Secrete Exosomes Derived from Multivesicular Bodies?

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PLANT SIGNALING & BEHAVIOR (2007)

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The role of CD4+CD25+ T cells in autoantibody production in murine lupus

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CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2006)

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EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation

IJ White et al.

EMBO JOURNAL (2006)

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Inhibition of NFκB activation with curcumin attenuates plasma inflammatory cytokines surge and cardiomyocytic apoptosis following cardiac ischemia/reperfusion

CH Yeh et al.

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Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells

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Advances in immunology - Autoimmune diseases

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