Journal
MOLECULES
Volume 28, Issue 15, Pages -Publisher
MDPI
DOI: 10.3390/molecules28155864
Keywords
antioxidants; extraction; green methodologies; biological activity; nanoencapsulation; plant extracts; phenolic compounds; colloids
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This review provides updated research on the bioactivity of rutin, a dietary flavonol, and the limitations in its industrial use. Novel encapsulation systems have been developed to expand its applications and preserve its biological activity. The review also covers extraction sources and methodologies, quantitative analysis techniques, encapsulation methods, and industrial applications.
In vitro and in vivo studies have demonstrated the bioactivity of rutin, a dietary flavonol naturally found in several plant species. Despite widespread knowledge of its numerous health benefits, such as anti-inflammatory, antidiabetic, hepatoprotective and cardiovascular effects, industrial use of rutin is still limited due to its low solubility in aqueous media, the characteristic bitter and astringent taste of phenolic compounds and its susceptibility to degradation during processing. To expand its applications and preserve its biological activity, novel encapsulation systems have been developed. This review presents updated research on the extraction sources and methodologies of rutin from fruit and vegetable products commonly found in a regular diet and grown using family farming approaches. Additionally, this review covers quantitative analysis techniques, encapsulation methods utilizing nanoparticles, colloidal and heterodisperse systems, as well as industrial applications of rutin.
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