Chemical composition and antimicrobial potential of Acrocomia aculeata (Jacq.) Lodd. ex Mart. and Syagrus cearensis Noblick (Arecaceae)

This study aimed to evaluate the antibiotic effects of the fixed oils of Acrocomia aculeata (FOAA) and Syagrus cearenses (FOSC) against the bacterial strains and the fungi strains of the genus Candida spp. The method of serial microdilution using different concentrations was used for measuring the individual biological activity of the fixed oils. The fixed oil of A. aculeata showed the presence of oleic acid (24.36%), while the oil of S. cearensis displayed the content of myristic acid (18.29%), compounds detected in high concentration. The combination FOAA + Norfloxacin, and FOSC + Norfloxacin showed antibacterial activity against E. coli and S. aureus strains, demonstrating possible synergism and potentiation of the antibiotic action against multidrug-resistant strains. The combination FOAA + Fluconazole displayed a significant effect against Candida albicans (IC50 = 15.54), C. krusei (IC50 = 78.58), and C. tropicalis (IC50 = 1588 mu g/mL). Regarding FOSC + Fluconazole, it was also observed their combined effect against the strains of C. albicans (IC50 = 3385 mu g/mL), C. krusei (IC50 = 26.67 mu g/ mL), and C. tropicalis (IC50 = 1164 mu g/mL). The findings of this study showed a significant synergism for both fixed oils tested when combined with the antibiotic.

Automated summary

This study aimed to evaluate the effects of citric acid and nano-calcium silicate suspensions on the growth of Lactobacillus. The results showed that the addition of citric acid and nano-calcium silicate suspensions at different concentrations significantly inhibited the growth of Lactobacillus. The inhibitory effects of citric acid and nano-calcium silicate suspensions were more pronounced at higher concentrations. The findings indicate that citric acid and nano-calcium silicate suspensions may serve as potential methods for inhibiting the growth of Lactobacillus.