Journal
MEDICAL CLINICS OF NORTH AMERICA
Volume 108, Issue 1, Pages 79-92Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mcna.2023.05.016
Keywords
FUO; Fever of unknown origin; PUO; Prolonged fever
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Fevers of unknown origin (FUO) present a diagnostic challenge, with a wide range of potential causes including infectious, autoimmune, and malignant. Some adolescents with FUO may never have an identifiable etiology, but the prognosis is generally favorable in the absence of red flag symptoms.
Fevers of unknown origin (FUO) remain a diagnostic dilemma. The differential remains broad with etiology most commonly including infectious, autoimmune, and malignant related. A significant portion of adolescents with FUO may never have an identifiable etiology found. However, the prognosis of FUO without determined etiology and in the absence of red flag symptoms is overall reassuring.
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