4.6 Article

The numerical solution of the free-boundary cell motility problem

Journal

MATHEMATICS AND COMPUTERS IN SIMULATION
Volume 217, Issue -, Pages 327-337

Publisher

ELSEVIER
DOI: 10.1016/j.matcom.2023.10.015

Keywords

Finite differences; Free boundary problems; Mathematical modeling; Non-uniform grid; Partial differential equations

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The paper introduces a simple 2D model for describing the cell motility on a homogeneous isotropic surface. The model incorporates the dynamics of complex actomyosin liquid, which affects the boundary dynamics and cell motility. It consists of a system of equations with a free boundary domain and includes a non-local term. The numerical solution of this model is presented in this work.
The cell motility problem has been investigated for a long time. Today, many biologists, physicists, and mathematicians are looking for new research instruments for this process. A simple 2D model of a free-boundary cell moving on a homogeneous isotropic surface is presented in the paper. It describes the dynamics of the complex actomyosin liquid, whose special properties influence the boundary dynamics and cell motility. The model consists of a system of equations with the free boundary domain and contains a non-local term. In this work, we a numerical solution of this

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