4.6 Article

Construction of a polydopamine-MnO2 functionalized metal–organic framework for synergistic photothermal/NO/nanocatalytic antibacterial therapy

Related references

Note: Only part of the references are listed.
Review Chemistry, Multidisciplinary

Metal-Based Nanozymes with Multienzyme-Like Activities as Therapeutic Candidates: Applications, Mechanisms, and Optimization Strategy

Dan Li et al.

Summary: Most nanozymes developed for medical applications lack sufficient catalytic activity and functionality in complex pathological microenvironments due to their single-enzyme-like activity. Metal-based nanozymes with multienzyme-like activities (MNMs) can mimic two or more activities of natural enzymes, effectively catalyzing cascade reactions or multiple substrates simultaneously. These MNMs can adapt to different catalytic conditions, producing substrates for downstream catalytic reactions and overcoming the limitation of insufficient substrates in the microenvironment. As a result, MNMs have stronger antitumor, antibacterial, and anti-inflammatory effects in preclinical models. This review summarizes the cellular effects and underlying mechanisms of MNMs, and discusses their potential medical utility and optimization strategy for clinical applications, providing a theoretical reference for the design, development, and therapeutic application of their catalytic effects.

SMALL (2023)

Review Nanoscience & Nanotechnology

Biomaterial-based antimicrobial therapies for the treatment of bacterial infections

Pranav P. Kalelkar et al.

Summary: This review discusses the use of antibacterial biomaterials and non-antibiotic therapies to improve the ability to combat antibiotic resistance and recurring infections. Utilizing biomaterials allows for targeted delivery of multiple agents while reducing systemic adverse effects, showing great potential for future development.

NATURE REVIEWS MATERIALS (2022)

Article Engineering, Environmental

Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives

Xianjin Hu et al.

Summary: The increase in drug resistant bacteria poses challenges to the treatment of infectious diseases. Photodynamic therapy (PDT) is a promising antimicrobial strategy that does not induce bacterial resistance. However, antibacterial PDT (APDT) has limitations, thus synergistic strategies with other treatments can enhance antimicrobial efficacy.

CHEMICAL ENGINEERING JOURNAL (2022)

Article Materials Science, Multidisciplinary

Prussian blue and collagen loaded chitosan nanofibers with NIR-controlled NO release and photothermal activities for wound healing

Wenyu Wang et al.

Summary: A novel composite nanofibrous scaffold was developed using prussian blue nanoparticles and Type I collagen, showing excellent abilities to accelerate wound healing in the wound healing processes. Histological analysis demonstrated that the scaffold promoted fibroblast growth and accelerated epithelialization.

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2021)

Article Engineering, Environmental

An overview of the use of nanozymes in antibacterial applications

Linqiang Mei et al.

Summary: The emergence of nanozymes as promising candidates for combating bacteria is driven by their combination of advantages from nanomaterials and natural enzymes, resulting in low cost, good stability, controllable size, easy preparation, multifunctionality, and superior catalytic activity, making them potent antibacterial agents with broad-spectrum antibacterial abilities and biocompatibility.

CHEMICAL ENGINEERING JOURNAL (2021)

Article Materials Science, Biomaterials

Manganese dioxide nanozyme for reactive oxygen therapy of bacterial infection and wound healing

Li Liu et al.

Summary: The research team has developed a nanozyme that generates reactive oxygen species with high stability and biocompatibility, effectively killing multidrug resistant pathogens, preventing and disrupting biofilm formation, and demonstrating excellent antibacterial performance. This oxidative therapy based nanozyme shows promising potential in treating skin and soft tissue infections in mice.

BIOMATERIALS SCIENCE (2021)

Review Chemistry, Multidisciplinary

Emerging photothermal-derived multimodal synergistic therapy in combating bacterial infections

Jingjing Huo et al.

Summary: Given the challenges of bacterial resistance and biofilm protection, photothermal therapy (PTT)-derived multimodal synergistic treatments have emerged as a promising approach to combat bacterial infections. By combining PTT with chemotherapy, photo-dynamic/catalytic therapy, immunotherapy, and sonodynamic therapy, enhanced bactericidal activity can be achieved while minimizing potential side effects.

CHEMICAL SOCIETY REVIEWS (2021)

Review Chemistry, Multidisciplinary

Nanomaterials-based photothermal therapy and its potentials in antibacterial treatment

Yuan Chen et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Engineering, Biomedical

Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens

Rajamani Lakshminarayanan et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Review Pharmacology & Pharmacy

Fighting bacterial infections-Future treatment options

Jenny Fernebro

DRUG RESISTANCE UPDATES (2011)