Deciphering MnOx nanoparticles: A comprehensive analysis reveals Mn2O3 as the most cytotoxic variant in cellular systems

Article Nanoscience & Nanotechnology

Mesoporous Manganese Oxides with High-Valent Mn Species and Disordered Local Structures for Efficient Oxygen Electrocatalysis

Young Jin Sa et al.

Summary: In this study, four different mesoporous manganese oxides were synthesized and used as model catalysts to investigate the effects of local structures and Mn valence states on the activity of oxygen electrocatalysis. The results showed that for the oxygen reduction reaction, m-Mn2O3 exhibited the highest activity, followed by m-MnO2, m-MnO, and m-Mn3O4. For the oxygen evolution reaction, m-MnO2 showed the highest activity, followed by m-Mn2O3, while m-MnO and m-Mn3O4 had lower activity. These findings suggest that high-valent Mn species and disordered atomic arrangements induced by nanostructuring significantly affect electrocatalysis.

ACS APPLIED MATERIALS & INTERFACES (2023)

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Article Biochemistry & Molecular Biology

Comparative Evaluation of the Cytotoxic Effects of Metal Oxide and Metalloid Oxide Nanoparticles: An Experimental Study

Marina P. Sutunkova et al.

Summary: Industrial production generates complex aerosols with ultrafine particles, which are dangerous components of inhaled air. This study investigated the cytotoxicity of different nanoparticles based on their chemical nature and dose. Tests on rats exposed to nanoparticles of CuO, PbO, CdO, Fe2O3, NiO, SiO2, Mn3O4, and SeO were conducted, and it was found that cytotoxicity varied depending on the chemical nature and dose of the nanoparticles. Changes in cytological and biochemical parameters of bronchoalveolar lavage fluid were observed, indicating the cytotoxic effects of nanoparticles. These findings suggest that cytological and biochemical analysis can be used to predict the potential danger of new nanomaterials.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

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Review Nanoscience & Nanotechnology

Transition metal-based nanoparticles as potential antimicrobial agents: recent advancements, mechanistic, challenges, and future prospects

Sonali Gautam et al.

Summary: The transmission of bacteria poses potential risks for communicable diseases, necessitating the development of promising antibiotics. Traditional drugs have limited effectiveness and frequent administration leads to reduced effectiveness and the development of resistance. Nanoparticles (NPs) with distinct physiochemical characteristics and biocompatibility can play a pivotal role in managing medical situations by exhibiting extraordinary antibacterial effects. Metallic NPs, particularly those based on Mn, Fe, Co, Cu, and Zn metals, have wide-ranging antibacterial efficacy and show promise as therapeutic agents. This review explores the types of metal NPs employed as antimicrobial agents and their mechanisms, as well as discussing the challenges and future prospects of NPs in biological applications.

DISCOVER NANO (2023)

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Article Chemistry, Multidisciplinary

Preparation of Manganese Oxide Nanoparticles with Enhanced Capacitive Properties Utilizing Gel Formation Method

Md. Abu Bakar Siddique et al.

Summary: The development of efficient and environmentally friendly materials for energy storage is crucial. In this study, nanostructured MnO2 was successfully synthesized and its applicability in electrochemical capacitors was investigated. The results showed that the calcinated MNO7 exhibited higher specific capacitance, energy density, and power density compared to MNO4, and its nano-tablet-like structure and porous morphology were attributed to its superior capacitive behavior.

ACS OMEGA (2022)

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Review Toxicology

Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology

Chukwuebuka Egbuna et al.

Summary: This review provides a comprehensive update on the toxic effects of nanoparticles, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. Recent studies have shown that nanoparticles can lead to serious health effects when exposed to the body through ingestion, inhalation, and skin contact without caution. The toxicity of nanoparticles depends on properties such as their nature, size, surface area, shape, aspect ratio, surface coating, crystallinity, dissolution, and agglomeration.

JOURNAL OF TOXICOLOGY (2021)

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Article Environmental Sciences