Microwave-induced synthesis of zinc-phthalocyanine with improved photosensitizing potential

In this paper, an efficient and environmentally friendly approach to the microwave-assisted synthesis of zinc phthalocyanine (ZnPc) was developed to compare the features and changes in morphology, phase, and optical properties with crystals obtained under conventional synthesis. Well-crystallized with high yield and purity ZnPc in & beta;-form was obtained by fast and efficient microwave-assisted procedure after five minutes of microwave heating. Studies including electron paramagnet resonance (EPR) indicated the improved photosensitizing potential of microwave-produced crystals, creating viable candidates for photodynamic treatment. Gamma rays aftereffect confirmed the stability of the ZnPc making them versatile in their application in medicine and sophisticated technology.

Automated summary

In this paper, an efficient and environmentally friendly microwave-assisted synthesis method for zinc phthalocyanine (ZnPc) was developed. The obtained ZnPc crystals showed well-crystallized β-form with high yield and purity after microwave heating for five minutes. Studies including EPR indicated improved photosensitizing potential of microwave-produced crystals, making them viable candidates for photodynamic treatment. The stability of ZnPc was confirmed by gamma rays aftereffect, making them versatile in applications in medicine and sophisticated technology.