Investigation of silver-doped binary glass through modified Stober process under surfactant

A native glass nanoparticle composition based on a binary system, BGNPs, was synthesized by a modified Stober process under surfactant. Afterward, the glass was doped with silver (Ag), and their acellular bioactivity was studied. The synthesized bioactive glasses were characterized by thermogravimetric analysis (TGA), Fourier Transform Infrared Spectroscopy (FTIR), Brunauer-Emmet-Teller (BET) and Barrett-Joyner-Halenda (BJH), X-Ray diffraction (XRD), nuclear magnetic resonance (NMR) and Scanning Electron Microscope attached with Energy-dispersive X-ray spectroscopy (SEM-EDS). Further, biological properties were analyzed before and after in-vitro tests by soaking the as-prepared bioglass nanoparticles in simulated body fluid (SBF) for different periods. Apatite layers covered the surface of the prepared nanoparticles, indicating their bioactivity from SEM images. Also, the pore size distribution of nano-spheroids particle sizes was within the range of 2-5 nm, and quantitative results from the EDS confirmed the Ag-doped in BGNPs, and both SEM and XRD spectra validated the above results. Using silver-doped prepared glasses, promising results were obtained regarding apatite formation.

Automated summary

A native glass nanoparticle composition called BGNPs, based on a binary system, was synthesized using a modified Stober process with a surfactant. The glass was then doped with silver (Ag) and its acellular bioactivity was studied. The characterization of the bioactive glasses was done using various techniques including TGA, FTIR, BET and BJH, XRD, NMR, and SEM-EDS. The results showed the formation of apatite layers on the surface of the nanoparticles, indicating their bioactivity, and confirmed the presence of Ag-doped BGNPs.