A closer look at jGCaMP8

Unlocking the secrets of the brain requires high precision tools to record neuronal activity. Neuroscientists have tools to capture neuronal activity with unprecedented speed, precision and fidelity. Thanks to a ground-breaking redesign of the linker peptide of GCaMP proteins, a domain seldomly considered for optimization, a new sensor bridges the gap between calcium imaging and electrophysiology.

Automated summary

Unlocking the secrets of the brain requires precise tools to capture neuronal activity. Neuroscientists now have unprecedented tools to record activity with speed, precision, and fidelity. A new sensor, created through redesigning the linker peptide of GCaMP proteins, bridges the gap between calcium imaging and electrophysiology.