Travel-related giardiasis: incidence and time trends for various destination countries

Article Public, Environmental & Occupational Health

Persistent abdominal symptoms in returning travellers: clinical and molecular findings

Shiraz Gefen-Halevi et al.

Summary: This study investigated the clinical features and prevalence of gastrointestinal protozoa in returning travellers with persistent abdominal symptoms. The results showed that more than one-third of returning travellers had gastrointestinal protozoa, with Blastocystis hominis and Dientamoeba fragilis being the most common. Additionally, the Indian subcontinent was identified as the main source of Giardia lamblia infection.

JOURNAL OF TRAVEL MEDICINE (2022)

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Review Public, Environmental & Occupational Health

Treatment strategies for nitroimidazole-refractory giardiasis: a systematic review

Daniel L. Bourque et al.

Summary: This review aims to summarize the literature on pharmacotherapy for nitroimidazole-refractory giardiasis. The included studies demonstrate a heterogeneous approach to treatment, with quinacrine appearing to be highly effective. However, more data on its safety are needed.

JOURNAL OF TRAVEL MEDICINE (2022)

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Article Public, Environmental & Occupational Health

Giardiasis Outbreaks — United States, 2012–2017

Erin E. Conners et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Article Public, Environmental & Occupational Health

Risk factors for and management of metronidazole-refractory giardiasis in international travellers: A retrospective analysis

Tanja E. Peters et al.

Summary: This study analyzed 339 cases of returning travellers with confirmed giardiasis between 2007 and 2016 in Hamburg, Germany, finding a significantly higher risk of treatment failure with metronidazole for patients returning from South Asia. Second-line treatment regimens showed inconsistency and unsatisfactory results, suggesting a need for reevaluation of treatment strategies for giardiasis. Prospective trials are urgently needed to assess new first-line treatment options and improve second-line treatment strategies.

TRAVEL MEDICINE AND INFECTIOUS DISEASE (2021)

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Review Infectious Diseases