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Application of multigene panel detection in breast cancer

Journal

JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
Volume 73, Issue 9, Pages 1862-1868

Publisher

PAKISTAN MEDICAL ASSOC
DOI: 10.47391/JPMA.6830

Keywords

Multigene panel testing; Breast cancer; Oncotype Dx; MammaPrint; Endopredict; PAM50; BCI; CancerSeek

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Precision medicine is the future direction of medical development, especially in cancer diagnosis and treatment. The application scope of multigene panel testing in breast cancer is expanding and providing guidance for clinical decision-making. There are promising prospects for broader applications in the future.
Precision medicine will be the direction of future medical development, especially in cancer diagnosis and treatment. With the deepening of breast cancer-related research, new factors related to diagnosis, treatment and prognosis are constantly being discovered. Researchers combine different factors to form a multigene panel testing, guiding clinicians' decision-making. The application scope of multigene panel detection is constantly expanding. At present, it has been tried in the prognosis evaluation of lymph node-positive and human epidermal growth factor receptor 2- positive breast cancer patients and the early screening of breast cancer. With continuous technological advancement, there will be broader application prospects in the future. The current narrative review was planned to evaluate the recent advances in applying multigene panel testing in breast cancer cases.

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