Related references
Note: Only part of the references are listed.Cancer Statistics, 2015
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2015)
Phosphorylation of FADD by the kinase CK1α promotes KRASG12D- induced lung cancer
Brittany M. Bowman et al.
SCIENCE SIGNALING (2015)
Phosphorylation of FADD by the kinase CK1α promotes KRASG12D- induced lung cancer
Brittany M. Bowman et al.
SCIENCE SIGNALING (2015)
Aurora kinase A mediates c-Myc's oncogenic effects in hepatocellular carcinoma
Longfeng Lu et al.
MOLECULAR CARCINOGENESIS (2015)
Aurora kinase inhibitor patents and agents in clinical testing: an update (2011-2013)
Chun Hei Antonio Cheung et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2014)
The role of mitotic kinases in coupling the centrosome cycle with the assembly of the mitotic spindle
Gang Wang et al.
JOURNAL OF CELL SCIENCE (2014)
The Prognostic Impact of KRAS, Its Codon and Amino Acid Specific Mutations, on Survival in Resected Stage I Lung Adenocarcinoma
Benjamin Izar et al.
JOURNAL OF THORACIC ONCOLOGY (2014)
Drugging the undruggable RAS: Mission Possible?
Adrienne D. Cox et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Increased Aurora B activity causes continuous disruption of kinetochore-microtubule attachments and spindle instability
Marta Munoz-Barrera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors
Chun-Nan Yeh et al.
ONCOTARGET (2014)
Chromosome Instability Modulated by BMI1-AURKA Signaling Drives Progression in Head and Neck Cancer
Chun-Hung Chou et al.
CANCER RESEARCH (2013)
Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
Ignacio Perez de Castro et al.
CANCER RESEARCH (2013)
The Investigational Aurora Kinase A Inhibitor MLN8237 Induces Defects in Cell Viability and Cell-Cycle Progression in Malignant Bladder Cancer Cells In Vitro and In Vivo
Ning Zhou et al.
CLINICAL CANCER RESEARCH (2013)
Let7a inhibits the growth of endometrial carcinoma cells by targeting Aurora-B
Ping Liu et al.
FEBS LETTERS (2013)
RAS promotes tumorigenesis through genomic instability induced by imbalanced expression of Aurora-A and BRCA2 in midbody during cytokinesis
Gong Yang et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Aurora-B overexpression is correlated with aneuploidy and poor prognosis in non-small cell lung cancer
Masafumi Takeshita et al.
LUNG CANCER (2013)
Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle
Helfrid Hochegger et al.
OPEN BIOLOGY (2013)
Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target
Ami V. Patel et al.
CLINICAL CANCER RESEARCH (2012)
Danusertib, an aurora kinase inhibitor
Hielke J. Meulenbeld et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)
Aurora kinase inhibitors: Progress towards the clinic
Madhu Kollareddy et al.
INVESTIGATIONAL NEW DRUGS (2012)
LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy
Emmanuel O. Johnson et al.
JOURNAL OF CELL SCIENCE (2012)
Aurora B kinase phosphorylates and instigates degradation of p53
Chris P. Gully et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Aurora B: A New Prognostic Marker and Therapeutic Target in Cancer
G. Portella et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy
Anat Biran et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation
Marco Lo Iacono et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
RAS oncogenes: weaving a tumorigenic web
Yuliya Pylayeva-Gupta et al.
NATURE REVIEWS CANCER (2011)
Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state
Juergen den Hollander et al.
BLOOD (2010)
ALK Inhibition for Non-Small Cell Lung Cancer: From Discovery to Therapy in Record Time
David E. Gerber et al.
CANCER CELL (2010)
RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance
Reda Hadj-Slimane et al.
CELLULAR SIGNALLING (2010)
Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition
Tony Sourisseau et al.
EMBO MOLECULAR MEDICINE (2010)
Aurora-A Phosphorylates, Activates, and Relocalizes the Small GTPase RalA
Kian-Huat Lim et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer
Christopher P. Gully et al.
MOLECULAR CANCER (2010)
Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway
Ya-Shih Tseng et al.
BMC CANCER (2009)
Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis
Xiaoxia Wang et al.
CANCER BIOLOGY & THERAPY (2009)
AZD1152 Rapidly and Negatively Affects the Growth and Survival of Human Acute Myeloid Leukemia Cells In vitro and In vivo
Adedayo Oke et al.
CANCER RESEARCH (2009)
Deregulated Aurora-B induced tetraploidy promotes tumorigenesis
Hao G. Nguyen et al.
FASEB JOURNAL (2009)
Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
Jeffrey A. Engelman et al.
CLINICAL CANCER RESEARCH (2008)
Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis
Satoshi Hayama et al.
CANCER RESEARCH (2007)
Roles of aurora kinases in mitosis and tumorigenesis
Jingyan Fu et al.
MOLECULAR CANCER RESEARCH (2007)
Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells
Kian-Huat Lim et al.
CURRENT BIOLOGY (2006)
Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation
X. Wang et al.
ONCOGENE (2006)
Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients
Barbara Vischioni et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Does the tumor microenvironment influence radiation-induced apoptosis?
Alistair Hunter et al.
APOPTOSIS (2006)
SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors
NM Heron et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation
A Kanda et al.
ONCOGENE (2005)
Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability
SL Smith et al.
BRITISH JOURNAL OF CANCER (2005)
Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis
M Tatsuka et al.
ONCOGENE (2005)
Progress in the development of selective inhibitors of aurora kinases (vol 5, pg 199, 2005)
A Mortlock et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
EA Harrington et al.
NATURE MEDICINE (2004)
Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACl rats
JJ Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models
DW Zhang et al.
ONCOGENE (2004)
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53
H Katayama et al.
NATURE GENETICS (2004)
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
R Bayliss et al.
MOLECULAR CELL (2003)
A novel mechanism for activation of the protein kinase aurora A
PA Eyers et al.
CURRENT BIOLOGY (2003)
Immortalization and transformation of primary human airway epithelial cells by gene transfer
AS Lundberg et al.
ONCOGENE (2002)
Share Paper
