☆ 4.8 Article

Gold Microbeads Enabled Proximity Electrochemiluminescence for Highly Sensitive and Size-Encoded Multiplex Immunoassays

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Multidisciplinary

Electrochemiluminescence Distance and Reactivity of Coreactants Determine the Sensitivity of Bead-Based Immunoassays

Yafeng Wang et al.

Summary: In this study, the electrochemiluminescence (ECL) generation by Ru(bpy)(3)(2+) and five tertiary amine coreactants was investigated. The ECL distance and reactivity of the coreactants were measured, and the integrated ECL intensity was used to quantitatively evaluate the reactivity. Statistical analysis of ECL images of labeled microbeads showed that the ECL distance and reactivity of the coreactant determine the emission intensity and sensitivity of immunoassay. BIS-TRIS was found to balance the trade-off between ECL distance and reactivity, resulting in a 236% increase in sensitivity compared to TPrA in the bead-based immunoassay of carcinoembryonic antigen.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2023)

Add to Collection

Article Chemistry, Applied

An electrochemiluminescence imaging sensor for the analysis of lactate in foods via a single gold microsphere

Gen Liu et al.

Summary: To address concerns about food safety, a fast and high-throughput lactate determination method is urgently needed. In this study, a novel electrochemiluminescence (ECL) imaging sensor based on a single gold microsphere with lactate oxidase (LOD) was developed. The sensor achieved sensitive detection of lactate by visually measuring the ECL intensity at a single gold microsphere. It exhibited a good linear relationship in the range of 0.1-50 mM of lactate, with a detection limit of 0.02 mM (S/N = 3).

JOURNAL OF FOOD COMPOSITION AND ANALYSIS (2023)

Add to Collection

Article Chemistry, Multidisciplinary

Single Cell Imaging of Electrochemiluminescence-Driven Photodynamic Therapy

Ming-Ming Chen et al.

Summary: We report a photodynamic therapy driven by electrochemiluminescence (ECL) with potential clinical applications. The ECL-generated luminescence acts as both optical readout and light source for the excitation of photosensitizer to produce reactive oxygen species (ROS). Real-time monitoring of cellular processes during ECL-PDT was achieved using ECL microscopy with high spatiotemporal resolution.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Add to Collection

Article Chemistry, Multidisciplinary

A redox-mediator pathway for enhanced multi-colour electrochemiluminescence in aqueous solution

Emily Kerr et al.

Summary: A novel 'redox mediator' pathway utilizing fac-[Ir(sppy)(3)](3-) has been discovered to significantly enhance the ECL reaction of [Ru(bpy)(3)](2+) and tri-n-propylamine. The green emission of [Ir(sppy)(3)](3-)* allows for internal standardization of the reaction, enabling superior sensitivity and precision for low-cost, portable ECL-based analytical devices when using a digital camera as the photodetector.

CHEMICAL SCIENCE (2022)

Add to Collection

Article Chemistry, Analytical

Gold Nanowires Array-Based Closed Bipolar Nanoelectrode System for Electrochemiluminescence Detection of α-Fetoprotein on Cell Surface

Xiuxiu Li et al.

Summary: In this study, a gold nanowires array-based closed bipolar electrodes (c-BPEs) system was developed for sensitive detection of cell surface proteins. The system exhibited high sensitivity and was able to detect specific proteins at extremely low concentrations, as well as detect living cells through a synergistic amplification effect.

ANALYTICAL CHEMISTRY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

In Situ Imaging of Endogenous Hydrogen Peroxide Efflux from Living Cells via Bipolar Gold Nanoelectrode Array and Electrochemiluminescence Technology

Xiuxiu Li et al.

Summary: This study proposes a gold nanorod array based electrochemiluminescence system for in situ imaging of endogenous hydrogen peroxide (H2O2) released from living cells and detecting other molecules through cell surface modification. It has potential applications in cell apoptosis study and disease diagnosis.

ACS SENSORS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Dual Intramolecular Electron Transfer for In Situ Coreactant-Embedded Electrochemiluminescence Microimaging of Membrane Protein

Ningning Wang et al.

Summary: This study developed a new strategy and system using TEA-Pdots to embed coreactants in the ECL mechanism, leading to significantly improved ECL emission strength. The system can be used for in situ ECL microimaging on single living cells without the need for additional permeable treatment.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Microtube Electrodes for Imaging the Electrochemiluminescence Layer and Deciphering the Reaction Mechanism

Weiliang Guo et al.

Summary: The study utilized microtube electrode (MTE) and microscopy to measure the thickness of ECL layer (TEL) in order to decipher reaction mechanisms. Different systems exhibited varying changes in ECL pattern and TEL, with the catalytic route playing a significant role in these variations.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Analytical

Hierarchical Metal-Organic Framework-Confined CsPbBr3 Quantum Dots and Aminated Carbon Dots: A New Self-Sustaining Suprastructure for Electrochemiluminescence Bioanalysis

Yue Cao et al.

Summary: A self-sustaining suprastructure was constructed by loading aminated carbon dots and CsPbBr3 perovskite quantum dots into hierarchical zeolite imidazole framework-8, resulting in improved stability and enhanced electrochemiluminescence efficiency. This ternary nanocomposite opens up new possibilities for the advancement of perovskite-based ECL emitters and their applications in the ECL domain.

ANALYTICAL CHEMISTRY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Bio-Coreactant-Enhanced Electrochemiluminescence Microscopy of Intracellular Structure and Transport

Cheng Ma et al.

Summary: The bio-coreactant-enhanced electrochemiluminescence (ECL) microscopy allows for ECL imaging of intracellular structure and dynamic transport by using Ru(bpy)(3)(2+) and intracellular biomolecules. The research reveals the universal edge effect of cellular electroporation, as well as the dynamic transport of Ru(bpy)(3)(3+) in different cellular compartments and its correlation with the actin cytoskeleton.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Spatially Selective Imaging of Cell-Matrix and Cell-Cell Junctions by Electrochemiluminescence

Hao Ding et al.

Summary: A novel method for spatially selective imaging of cell junctions by regulating the thickness of the electrochemiluminescence (ECL) layer through control of luminophore and co-reactant concentrations has been reported. Low luminophore concentration reveals cell-matrix adhesions, while high concentration allows sequential imaging of cell-matrix and cell-cell junctions. This strategy not only provides new insights into ECL mechanisms but also expands the potential applications of ECL microscopy in bioimaging.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Single Biomolecule Imaging by Electrochemiluminescence

Yujie Liu et al.

Summary: This study successfully imaged single biomolecules using RuDSNs/AuNPs as ECL nanoemitters, demonstrating the visualization of single protein molecules and single membrane proteins in cells, overcoming the challenges in ultrasensitive ECL analysis and providing valuable information for cellular biology research.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Super-Resolution Electrogenerated Chemiluminescence Microscopy for Single-Nanocatalyst Imaging

Ming-Ming Chen et al.

Summary: The super-resolution ECLM technique allows for high-resolution imaging of single nanoparticles' catalytic activity, revealing surface characteristics of nanocatalysts. This technology has great potential applications in catalysis, biological imaging, and single-entity analysis.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Identifying Highly Photoelectrochemical Active Sites of Two Au21 Nanocluster Isomers toward Bright Near-Infrared Electrochemiluminescence

Mahdi Hesari et al.

Summary: The structures of two Au-21(SR)(15) nanocluster isomers determine their chemical reactivity, showing unprecedented ECL efficiencies. The relationships were explored using ECL and photoluminescence spectroscopy, elucidating photoelectrochemical reactivity and ECL mechanisms.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Pharmacology & Pharmacy

Visualization analysis of lecithin in drugs based on electrochemiluminescent single gold microbeads

Gen Liu et al.

Summary: The research describes a simple ECL method based on single gold microbeads for imaging lecithin concentration. Calibration curves were established to achieve a detection limit of 0.05 mM lecithin. This method offers advantages of high throughput, versatility, and low cost, showing potential applications in disease diagnostics, environmental monitoring, and food safety.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Shadow Electrochemiluminescence Microscopy of Single Mitochondria

Yumeng Ma et al.

Summary: This study introduces a label-free shadow electrochemiluminescence (ECL) microscopy technique to image single living mitochondria deposited on electrode surface. By utilizing negative optical contrast and local diffusional hindrance, this approach visualizes individual mitochondria and validates their functionality with classical fluorescent biomarkers. The versatility and extreme sensitivity of this method make it promising for imaging subcellular structures while alleviating photobleaching and phototoxicity issues associated with conventional microscopy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Imaging Cell-Matrix Adhesions and Collective Migration of Living Cells by Electrochemiluminescence Microscopy

Hao Ding et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Article Chemistry, Analytical

Electrogenerated Chemiluminescence in Submicrometer Wells for Very High-Density Biosensing

Chen Cui et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection

Review Chemistry, Analytical

Multiplexed Immunosensors and Immunoarrays

Abby Jones et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection

Article Chemistry, Analytical

Electrogenerated Chemiluminescence Biosensing

Honglan Qi et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Antifouling Strategies for Selective In Vitro and In Vivo Sensing

Cheng Jiang et al.

CHEMICAL REVIEWS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Multiplexed Luminescence Oxygen Channeling Immunoassay Based on Dual-Functional Barcodes with a Host-Guest Structure: A Facile and Robust Suspension Array Platform

Qingsheng Guo et al.

SMALL (2020)

Add to Collection

Article Multidisciplinary Sciences

Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance

Alessandra Zanut et al.

NATURE COMMUNICATIONS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Quantum Dots with Highly Efficient, Stable, and Multicolor Electrochemiluminescence

Zhiyuan Cao et al.

ACS CENTRAL SCIENCE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Dye-Doped Silica Nanoparticles for Enhanced ECL-Based Immunoassay Analytical Performance

Alessandra Zanut et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Article Chemistry, Multidisciplinary

A Robust Au-C≡C Functionalized Surface: Toward Real-Time Mapping and Accurate Quantification of Fe2+in the Brains of Live AD Mouse Models

Chuanping Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Hydrogen Evolution Reaction Monitored by Electrochemiluminescence Blinking at Single-Nanoparticle Level

Cheng Ma et al.

NANO LETTERS (2020)

Add to Collection

Article Chemistry, Physical

Neutral Dye-Doped Silica Nanoparticles for Electrogenerated Chemiluminescence Signal Amplification

Sagar Kesarkar et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2019)

Add to Collection

Review Chemistry, Multidisciplinary

Optical Multiplexed Bioassays for Improved Biomedical Diagnostics

Yong Fan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Electrochemiluminescence-Based Capacitance Microscopy for Label-Free Imaging of Antigens on the Cellular Plasma Membrane

Jingjing Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection

Review Biochemistry & Molecular Biology

Antifouling (Bio)materials for Electrochemical (Bio)sensing

Susana Campuzano et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Add to Collection

Article Chemistry, Multidisciplinary

A conceptual framework for the development of iridium(iii) complex-based electrogenerated chemiluminescence labels

Lifen Chen et al.

CHEMICAL SCIENCE (2019)

Add to Collection

Article Chemistry, Analytical

Au-Se-Bond-Based Nanoprobe for Imaging MMP-2 in Tumor Cells under a High-Thiol Environment

Xiaonan Gao et al.

ANALYTICAL CHEMISTRY (2018)

Add to Collection

Article Chemistry, Analytical

Automated 3D-Printed Microfluidic Array for Rapid Nanomaterial-Enhanced Detection of Multiple Proteins

Karteek Kadimisetty et al.

ANALYTICAL CHEMISTRY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Electrogenerated Chemiluminescence Imaging of Electrocatalysis at a Single Au-Pt Janus Nanoparticle

Meng-Jiao Zhu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Avoiding Thiol Compound Interference: A Nanoplatform Based on High-Fidelity Au-Se Bonds for Biological Applications

Bo Hu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Electrochemiluminescence for Electric-Driven Antibacterial Therapeutics

Shanshan Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

A single-electrode electrochemical system for multiplex electrochemiluminescence analysis based on a resistance induced potential difference

Wenyue Gao et al.

CHEMICAL SCIENCE (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Dynamically imaging collision electrochemistry of single electrochemiluminescence nano-emitters

Cheng Ma et al.

CHEMICAL SCIENCE (2018)

Add to Collection

Article Chemistry, Analytical

Spectrum-Resolved Triplex-Color Electrochemiluminescence Multiplexing Immunoassay with Highly-Passivated Nanocrystals as Tags

Jie Zhou et al.

ANALYTICAL CHEMISTRY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Potential-Resolved Multicolor Electrochemiluminescence for Multiplex Immunoassay in a Single Sample

Weiliang Guo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Surface-Confined Electrochemiluminescence Microscopy of Cell Membranes

Silvia Voci et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Single Cell Electrochemiluminescence Imaging: From the Proof-of-Concept to Disposable Device-Based Analysis

Giovanni Valenti et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Add to Collection

Article Chemistry, Analytical

Evaluating Metabolite-Related DNA Oxidation and Adduct Damage from Aryl Amines Using a Microfluidic ECL Array

Itti Bist et al.

ANALYTICAL CHEMISTRY (2017)

Add to Collection

Article Chemistry, Analytical

Spectrum-Resolved Dual-Color Electrochemiluminescence Immunoassay for Simultaneous Detection of Two Targets with Nanocrystals as Tags

Guizheng Zou et al.

ANALYTICAL CHEMISTRY (2017)

Add to Collection

Article Chemistry, Analytical

A ratiometric electrochemical strategy for sensitive determination of Furin activity based on dual signal amplification and antifouling nanosurfaces

Dazhi Yao et al.

ANALYST (2017)

Add to Collection

Review Electrochemistry

Review-Electrogenerated Chemiluminescence: Light Years Ahead

Mahdi Hesari et al.

JOURNAL OF THE ELECTROCHEMICAL SOCIETY (2016)

Add to Collection

Article Chemistry, Analytical

Spectrum-Based Electrochemiluminescent Immunoassay with Ternary CdZnSe Nanocrystals as Labels

Xin Zhang et al.

ANALYTICAL CHEMISTRY (2016)

Add to Collection

Article Chemistry, Multidisciplinary

In-electrode vs. on-electrode: ultrasensitive Faraday cage-type electrochemiluminescence immunoassay

Zhiyong Guo et al.

CHEMICAL COMMUNICATIONS (2016)

Add to Collection

Review Electrochemistry

Essential Role of Electrode Materials in Electrochemiluminescence Applications

Giovanni Valenti et al.

CHEMELECTROCHEM (2016)

Add to Collection

Article Chemistry, Analytical

Electrogenerated chemiluminescence of tris(2,2′ bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte

Noah Kebede et al.

ANALYST (2015)

Add to Collection

Article Chemistry, Physical

Numerical Simulation of Doped Silica Nanoparticle Electrochemiluminescence

Kenta Imai et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2015)

Add to Collection

Article Chemistry, Multidisciplinary

Highly Efficient Dual-Color Electrochemiluminescence from BODIPY-Capped PbS Nanocrystals

Mahdi Hesari et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Add to Collection

Article Chemistry, Multidisciplinary

Imaging Electrogenerated Chemiluminescence at Single Gold Nanowire Electrodes

Andrew J. Wilson et al.

NANO LETTERS (2015)

Add to Collection

Article Chemistry, Analytical

Magnetic-Encoded Fluorescent Multifunctional Nanospheres for Simultaneous Multicomponent Analysis

Erqun Song et al.

ANALYTICAL CHEMISTRY (2014)

Add to Collection

Article Chemistry, Analytical

Red-Green-Blue Electrogenerated Chemiluminescence Utilizing a Digital Camera as Detector

Egan H. Doeven et al.

ANALYTICAL CHEMISTRY (2014)

Add to Collection

Article Chemistry, Multidisciplinary

Selective Excitation of Concomitant Electrochemiluminophores: Tuning Emission Color by Electrode Potential

Egan H. Doeven et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Add to Collection

Article Chemistry, Multidisciplinary

Self-Enhanced Electrochemiluminescence of an Iridium(III) Complex: Mechanistic Insight

Kalen N. Swanick et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Add to Collection

Review Chemistry, Multidisciplinary

Applications and trends in electrochemiluminescence

Lianzhe Hu et al.

CHEMICAL SOCIETY REVIEWS (2010)

Add to Collection

Article Chemistry, Multidisciplinary

Multiplexed Sandwich Immunoassays Using Electrochemiluminescence Imaging Resolved at the Single Bead Level

Frederique Deiss et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Add to Collection

Review Chemistry, Multidisciplinary

Electrogenerated chemiluminescence and its biorelated applications

Wujian Miao

CHEMICAL REVIEWS (2008)

Add to Collection

Article Chemistry, Multidisciplinary

Environmentally friendly and highly sensitive Ruthenium(II) tris(2,2 '-bipyridyl) electrochemiluminescent system using 2-(dibutylamino) ethanol as co-reactant

Xiaoqing Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Add to Collection

Article Chemistry, Analytical

Electrogenerated chemiluminescence.: 80.: C-reactive protein determination at high amplification with [Ru(bpy)3]2+-containing microspheres

WJ Miao et al.

ANALYTICAL CHEMISTRY (2004)

Add to Collection

Review Chemistry, Multidisciplinary

Electrochemiluminescence (ECL)

MM Richter

CHEMICAL REVIEWS (2004)

Add to Collection

Article Chemistry, Multidisciplinary

Electrogenerated chemiluminescence 69:: The tris(2,2′-bipyridine)ruthenium(II), (Ru(bpy)32+)/tri-n-propylamine (TPrA) system revisited -: A new route involving TPrA•+ cation radicals

WJ Miao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Add to Collection

Article Chemistry, Analytical

Electrogenerated chemiluminescence.: 66.: The role of direct coreactant oxidation in the ruthenium tris(2,2′)bipyridyl/tripropylamine system and the effect of halide ions on the emission intensity

YB Zu et al.

ANALYTICAL CHEMISTRY (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.