Journal
MOLECULAR BIOSYSTEMS
Volume 12, Issue 2, Pages 328-333Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5mb00806a
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Funding
- National Nature Scientific Funding of China [81170190, 81372117]
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Arrhythmia, the basis of which is cardiomyocyte ion channel abnormalities, poses a serious threat to human health. A large number of studies have demonstrated that miRNA-1(miR-1) is involved in the occurrence of arrhythmia in many myocardial pathological conditions by post-transcriptionally regulating a variety of ion channels and proteins related to cardiac electrical activity. We aim at emphasizing the relationship between miR-1 and ion channels and proteins involved in the process of arrhythmia. In addition, we will pay attention to its future therapeutic prospects.
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