A simple and fast epinephrine voltammetry sensor using reduced graphene oxide and iron metal-organic framework

In this research, the metal-organic frameworks of iron (III) terephthalic acid (MIL-53-(Fe)) as well as graphene oxide were synthesized. The surface of the glassy carbon electrode was electrochemically modified by reduced graphene oxide and MIL(53)-Fe by cyclic voltammetry. The surface morphology of the modified electrodes was investigated by X-ray diffraction analysis, Fourier-transform infrared spectroscopy, energy dispersive X-ray analysis, and scanning electron microscopy techniques. The modified electrode was applied to determine epinephrine in the presence of uric acid. The electrode shows more sensitive response for epinephrine in the presence of uric acid than some unmodified electrodes. The detection limit and the linear range obtained for epinephrine determination were 89 nmol/L and 0.49 to 130.41 & mu;mol/L, respectively, which compared to other recent studies about epinephrine electrochemical sensors were completely suitable.

Automated summary

In this research, metal-organic frameworks of iron (III) terephthalic acid (MIL-53-(Fe)) and graphene oxide were synthesized. The glassy carbon electrode was electrochemically modified by reduced graphene oxide and MIL(53)-Fe using cyclic voltammetry. The modified electrode was used to detect epinephrine in the presence of uric acid, showing a more sensitive response compared to unmodified electrodes. The detection limit and linear range for epinephrine determination were 89 nmol/L and 0.49 to 130.41 μmol/L, respectively, making it suitable for epinephrine electrochemical sensors.